ATP and arterial calcification

New insights into NPP1 function: Lessons from clinical and animal studies

(2012) N.C.W. Mackenzie et al.   BONE

Mechanisms of ATP release and signalling in the blood vessel wall

(2012) A. W. Lohman et al.   CARDIOVASCULAR RESEARCH

P2Y Purinoceptors as Potential Emerging Therapeutical Target in Vascular Disease

(2012) Mirjam Schuchardt et al.   CURRENT PHARMACEUTICAL DESIGN

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

(2012) Alison Gartland et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Inhibition of ectonucleotidase with ARL67156 prevents the development of calcific aortic valve disease in warfarin-treated rats

(2012) Nancy Côté et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ATP acts as a survival signal and prevents the mineralization of aortic valve

(2012) Nancy Côté et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression

(2012) Gexin Zhao et al.   KIDNEY INTERNATIONAL

Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice

(2012) Neil Charles Wallace Mackenzie et al.   PLoS One

Cellular function and molecular structure of ecto-nucleotidases

(2012) Herbert Zimmermann et al.   Purinergic Signalling

Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle

(2011) Ricardo Villa-Bellosta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

(2011) Catherine M. Shanahan et al.   CIRCULATION RESEARCH

Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization

(2011) Alexander N. Kapustin et al.   CIRCULATION RESEARCH

The endothelium-derived contracting factor uridine adenosine tetraphosphate induces P2Y2-mediated pro-inflammatory signaling by monocyte chemoattractant protein-1 formation

(2011) Mirjam Schuchardt et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification

(2011) Mirjam Schuchardt et al.   KIDNEY INTERNATIONAL

Daily peritoneal administration of sodium pyrophosphate in a dialysis solution prevents the development of vascular calcification in a mouse model of uraemia

(2011) B. L. Riser et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

NT5EMutations and Arterial Calcifications

(2011) Cynthia St. Hilaire et al.   NEW ENGLAND JOURNAL OF MEDICINE

FGF23 is independently associated with vascular calcification but not bone mineral density in patients at various CKD stages

(2011) L. Desjardins et al.   OSTEOPOROSIS INTERNATIONAL

The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells

(2011) Dongxing Zhu et al.   PLoS One

Role of CD73 and extracellular adenosine in disease

(2011) Simon C. Robson   Purinergic Signalling

Autosomal-Recessive Hypophosphatemic Rickets Is Associated with an Inactivation Mutation in the ENPP1 Gene

(2010) Varda Levy-Litan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets

(2010) Bettina Lorenz-Depiereux et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Role of calcium-phosphate deposition in vascular smooth muscle cell calcification

(2010) Ricardo Villa-Bellosta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The ecto-nucleotidase NTPDase1 differentially regulates P2Y1 and P2Y2 receptor-dependent vasorelaxation

(2010) Gilles Kauffenstein et al.   BRITISH JOURNAL OF PHARMACOLOGY

Purinergic signalling and bone remodelling☆

(2010) Isabel R Orriss et al.   CURRENT OPINION IN PHARMACOLOGY

Coronary artery calcification and mortality in diabetic patients with proteinuria

(2010) Yi-Wen Chiu et al.   KIDNEY INTERNATIONAL

Treatment with pyrophosphate inhibits uremic vascular calcification

(2010) W Charles O'Neill et al.   KIDNEY INTERNATIONAL

Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia

(2009) Domenick A. Prosdocimo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition

(2009) Ritsuko Nakano-Kurimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse

(2009) Gilles Kauffenstein et al.   CARDIOVASCULAR RESEARCH

Vascular Calcification: The Killer of Patients with Chronic Kidney Disease

(2009) M. Mizobuchi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic Mineral Dysregulation Promotes Vascular Smooth Muscle Cell Adaptation and Extracellular Matrix Calcification

(2009) R. C. Shroff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasma pyrophosphate and vascular calcification in chronic kidney disease

(2009) W. C. O'Neill et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Expression, signaling, and function of P2X7 receptors in bone

(2009) Matthew W. Grol et al.   Purinergic Signalling

Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification

(2008) Michael S. Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypophosphatemia, Hyperphosphaturia, and Bisphosphonate Treatment Are Associated With Survival Beyond Infancy in Generalized Arterial Calcification of Infancy

(2008) Frank Rutsch et al.   Circulation-Cardiovascular Genetics

Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: Potential mechanism for uremic vascular calcification

(2008) K.A. Lomashvili et al.   KIDNEY INTERNATIONAL

Purinergic signalling

(2006) Geoffrey Burnstock   BRITISH JOURNAL OF PHARMACOLOGY