Dsc Orthologs Are Required for Hypoxia Adaptation, Triazole Drug Responses, and Fungal Virulence in Aspergillus fumigatus

Hypoxia and Fungal Pathogenesis: To Air or Not To Air?

(2012) Nora Grahl et al.   EUKARYOTIC CELL

Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA bindingand degradation

(2012) Joshua R. Porter et al.   MOLECULAR BIOLOGY OF THE CELL

SREBP-Dependent Triazole Susceptibility in Aspergillus fumigatus Is Mediated through Direct Transcriptional Regulation oferg11A(cyp51A)

(2011) Sara J. Blosser et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Yeast Sterol Regulatory Element-binding Protein (SREBP) Cleavage Requires Cdc48 and Dsc5, a Ubiquitin Regulatory X Domain-containing Subunit of the Golgi Dsc E3 Ligase

(2011) Emerson V. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yeast SREBP Cleavage Activation Requires the Golgi Dsc E3 Ligase Complex

(2011) Emerson V. Stewart et al.   MOLECULAR CELL

The Hypoxic Regulator of Sterol Synthesis Nro1 Is a Nuclear Import Adaptor

(2011) Tzu-Lan Yeh et al.   STRUCTURE

The virulence of the opportunistic fungal pathogenAspergillus fumigatusrequires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR)

(2011) Daryl L. Richie et al.   Virulence

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

(2011) Michael Blatzer et al.   PLoS Genetics

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis

(2010) Clara M. Bien et al.   EUKARYOTIC CELL

The Fungal Genetics Stock Center: a repository for 50 years of fungal genetics research

(2010) K. McCluskey et al.   JOURNAL OF BIOSCIENCES

Sterol Regulatory Element Binding Proteins (SREBPs): Controllers of Lipid Synthesis and Cellular Uptake

(2010) Michael S. Brown et al.   NUTRITION REVIEWS

Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast

(2009) Chih-Yung S Lee et al.   EMBO JOURNAL

Activation of Sterol Regulatory Element-binding Protein by the Caspase Drice inDrosophilaLarvae

(2009) Bilal Amarneh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degradation of Sterol Regulatory Element-binding Protein Precursor Requires the Endoplasmic Reticulum-associated Degradation Components Ubc7 and Hrd1 in Fission Yeast

(2009) Bridget T. Hughes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aspergillus fumigatusmetabolism: Clues to mechanisms ofin vivofungal growth and virulence

(2009) Sven D. Willger et al.   MEDICAL MYCOLOGY

Cryptococcus neoformansSite-2 protease is required for virulence and survival in the presence of azole drugs

(2009) Clara M. Bien et al.   MOLECULAR MICROBIOLOGY

Responses to hypoxia in fungal pathogens

(2008) Joachim F. Ernst et al.   CELLULAR MICROBIOLOGY

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens