Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy

Variability in the Androgen Response of Prostate Epithelium to 5 -Reductase Inhibition: Implications for Prostate Cancer Chemoprevention

(2010) E. A. Mostaghel et al.   CANCER RESEARCH

Evidence of Limited Contributions for Intratumoral Steroidogenesis in Prostate Cancer

(2010) J. Hofland et al.   CANCER RESEARCH

Phase II Multicenter Study of Abiraterone Acetate Plus Prednisone Therapy in Patients With Docetaxel-Treated Castration-Resistant Prostate Cancer

(2010) Daniel C. Danila et al.   JOURNAL OF CLINICAL ONCOLOGY

Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate

(2010) Alison H.M. Reid et al.   JOURNAL OF CLINICAL ONCOLOGY

Effect of Dutasteride on the Risk of Prostate Cancer

(2010) Gerald L. Andriole et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antitumor Activity with CYP17 Blockade Indicates That Castration-Resistant Prostate Cancer Frequently Remains Hormone Driven

(2009) G. Attard et al.   CANCER RESEARCH

Phase II Study of Androgen Synthesis Inhibition with Ketoconazole, Hydrocortisone, and Dutasteride in Asymptomatic Castration-Resistant Prostate Cancer

(2009) M.-E. Taplin et al.   CLINICAL CANCER RESEARCH

Activity of Dutasteride Plus Ketoconazole in Castration-Refractory Prostate Cancer After Progression on Ketoconazole Alone

(2009) Oliver Sartor et al.   Clinical Genitourinary Cancer

Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts

(2009) Jennifer A. Locke et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer

(2008) J. A. Locke et al.   CANCER RESEARCH

Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth

(2008) R. B. Montgomery et al.   CANCER RESEARCH

Effect of SLCO1B3 Haplotype on Testosterone Transport and Clinical Outcome in Caucasian Patients with Androgen-Independent Prostatic Cancer

(2008) A. Hamada et al.   CLINICAL CANCER RESEARCH

Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol

(2008) Paulette R. Dillard et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mechanisms mediating androgen receptor reactivation after castration

(2008) Xin Yuan et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS