Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK

Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors

(2012) S. Rottenberg et al.   CANCER RESEARCH

The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress

(2012) Manel Joaquin et al.   EMBO JOURNAL

Phosphorylated p38 and JNK MAPK proteins in hepatocellular carcinoma

(2012) Shen-Nien Wang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival

(2012) Tina M. Thornton et al.   International Journal of Biological Sciences

Cryptotanshinone induces ER stress-mediated apoptosis in HepG2 and MCF7 cells

(2011) In-Ja Park et al.   APOPTOSIS

Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy

(2011) Christophe Glorieux et al.   BIOCHEMICAL PHARMACOLOGY

Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

(2011) Robert Karisch et al.   CELL

Regulation of protein tyrosine phosphatases by reversible oxidation

(2011) Arne Östman et al.   JOURNAL OF BIOCHEMISTRY

p38α Mediates Cell Survival in Response to Oxidative Stress via Induction of Antioxidant Genes

(2011) Álvaro Gutiérrez-Uzquiza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

(2011) Bogdan Mateescu et al.   NATURE MEDICINE

Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

(2011) Eva M. Galan-Moya et al.   PLoS One

Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

(2011) A. T. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic analysis of specific and redundant roles for p38  and p38  MAPKs during mouse development

(2011) I. del Barco Barrantes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Cancer cell killing via ROS: To increase or decrease, that is the question

(2010) Jie Wang et al.   CANCER BIOLOGY & THERAPY

Mitochondrial ROS and radiation induced transformation in mouse embryonic fibroblasts

(2010) Changbin Du et al.   CANCER BIOLOGY & THERAPY

p38 Mitogen-Activated Protein Kinase Promotes Cell Survival in Response to DNA Damage but Is Not Required for the G2 DNA Damage Checkpoint in Human Cancer Cells

(2010) M. S. Phong et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of p38α unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism

(2009) Fulvio Chiacchiera et al.   Autophagy

Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation

(2009) Wei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804

(2009) Li Xing et al.   BIOCHEMISTRY

Inhibition of the p38 Kinase Suppresses the Proliferation of Human ER-Negative Breast Cancer Cells

(2009) L. Chen et al.   CANCER RESEARCH

p38  Mitogen-Activated Protein Kinase Is Essential for Skin Tumor Development in Mice

(2009) E. M. Schindler et al.   CANCER RESEARCH

A High-Throughput Pharmaceutical Screen Identifies Compounds with Specific Toxicity against BRCA2-Deficient Tumors

(2009) B. Evers et al.   CLINICAL CANCER RESEARCH

Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

(2009) David M. Goldstein et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-Inflammatory Properties of a Novel N-Phenyl Pyridinone Inhibitor of p38 Mitogen-Activated Protein Kinase: Preclinical-to-Clinical Translation

(2009) H. R. Hope et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

(2008) Wen-Sheng Wu et al.   CANCER AND METASTASIS REVIEWS

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

(2008) Stephen M. Keyse   CANCER AND METASTASIS REVIEWS

Reactive Oxygen Species-Mediated Pancreatic β-Cell Death Is Regulated by Interactions between Stress-Activated Protein Kinases, p38 and c-Jun N-Terminal Kinase, and Mitogen-Activated Protein Kinase Phosphatases

(2008) Ni Hou et al.   ENDOCRINOLOGY

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

(2007) Kohsuke Takeda et al.   Annual Review of Pharmacology and Toxicology