STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

(2010) Patrick G. Hogan et al.   Annual Review of Immunology

A Basic Sequence in STIM1 Promotes Ca2+Influx by Interacting with the C-Terminal Acidic Coiled Coil of Orai1

(2010) Nathaniel Calloway et al.   BIOCHEMISTRY

Essential Role for the CRAC Activation Domain in Store-dependent Oligomerization of STIM1

(2010) Elizabeth D. Covington et al.   MOLECULAR BIOLOGY OF THE CELL

A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells

(2010) Sonal Srikanth et al.   NATURE CELL BIOLOGY

The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels

(2010) C. Y. Park et al.   SCIENCE

Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

(2010) M. K. Korzeniowski et al.   Science Signaling

Calcium Signaling by STIM and Orai: Intimate Coupling Details Revealed

(2010) Y. Wang et al.   Science Signaling

Polarized but Differential Localization and Recruitment of STIM1, Orai1 and TRPC Channels in Secretory Cells

(2010) Jeong Hee Hong et al.   TRAFFIC

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Hydrophobicity at the N Terminus/Membrane Interface Impairs Gating of the Severe Combined Immunodeficiency-related ORAI1 Mutant

(2009) Isabella Derler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Determinants of the Coupling between STIM1 and Orai Channels

(2009) Irene Frischauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

STIM protein coupling in the activation of Orai channels

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Mechanistic Insights into STIM1-Mediated Initiation of Store-Operated Calcium Entry

(2008) Peter B. Stathopulos et al.   CELL

Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting β-cells

(2008) Natalia A. Tamarina et al.   CELL CALCIUM

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

Structural specificity in coiled-coil interactions

(2008) G GRIGORYAN et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Store-dependent and -independent Modes Regulating Ca2+Release-activated Ca2+Channel Activity of Human Orai1 and Orai3

(2008) Shenyuan L. Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

2-Aminoethoxydiphenyl Borate Alters Selectivity of Orai3 Channels by Increasing Their Pore Size

(2008) Rainer Schindl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stromal Interaction Molecule (STIM) 1 and STIM2 Calcium Sensing Regions Exhibit Distinct Unfolding and Oligomerization Kinetics

(2008) Peter B. Stathopulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Coupling of the Putative Coiled-coil Domain of ORAI1 with STIM1 Mediates ORAI1 Channel Activation

(2008) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry

(2008) Wayne I. DeHaven et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

(2008) Laura Navarro-Borelly et al.   JOURNAL OF PHYSIOLOGY-LONDON

2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels

(2008) Christine Peinelt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fifty years of coiled-coils and α-helical bundles: A close relationship between sequence and structure

(2008) David A.D. Parry et al.   JOURNAL OF STRUCTURAL BIOLOGY

Dynamic Movement of the Calcium Sensor STIM1 and the Calcium Channel Orai1 in Activated T-Cells: Puncta and Distal Caps

(2008) Valarie A. Barr et al.   MOLECULAR BIOLOGY OF THE CELL

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE