PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure

(2011) Peter Wehner et al.   DEVELOPMENT

Complex Interactions between GSK3 and aPKC in Drosophila Embryonic Epithelial Morphogenesis

(2011) Nicole A. Kaplan et al.   PLoS One

Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity

(2011) S. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome

(2010) T. Prebet et al.   BLOOD

An ATF2-based luciferase reporter to monitor non-canonical Wnt signaling in xenopus embryos

(2010) Bisei Ohkawara et al.   DEVELOPMENTAL DYNAMICS

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

(2010) Francesca Puppo et al.   EMBO REPORTS

Spatially defined Dsh-Lgl interaction contributes to directional tissue morphogenesis

(2010) N. A. Kaplan et al.   JOURNAL OF CELL SCIENCE

PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation

(2009) W. W. Yen et al.   DEVELOPMENT

XsFRP5 modulates endodermal organogenesis in Xenopus laevis

(2009) Katharina Damianitsch et al.   DEVELOPMENTAL BIOLOGY

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Membrane Bound Axin Is Sufficient for Wingless Signaling in Drosophila Embryos

(2009) N. S. Tolwinski   GENETICS

Epithelial Polarity: Interactions Between Junctions and Apical-Basal Machinery

(2009) N. A. Kaplan et al.   GENETICS

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

Asymmetric Homotypic Interactions of the Atypical Cadherin Flamingo Mediate Intercellular Polarity Signaling

(2008) Wei-Shen Chen et al.   CELL

PTK7 recruits dsh to regulate neural crest migration

(2008) I. Shnitsar et al.   DEVELOPMENT

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling