Ischaemic concentrations of lactate increase TREK1 channel activity by interacting with a single histidine residue in the carboxy terminal domain

Lactate: Brain Fuel in Human Traumatic Brain Injury: A Comparison with Normal Healthy Control Subjects

(2015) Thomas C. Glenn et al.   JOURNAL OF NEUROTRAUMA

Early decompressive surgery after combined intra-venous thrombolysis and endovascular stroke treatment

(2014) Ozcan Ozdemir et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Pericyte protection by edaravone after tissue plasminogen activator treatment in rat cerebral ischemia

(2014) Kentaro Deguchi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes

(2014) Eun Mi Hwang et al.   Nature Communications

Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

(2013) K. H. Lauritzen et al.   CEREBRAL CORTEX

Reducing hemorrhagic complication by dabigatran via neurovascular protection after recanalization with tissue plasminogen activator in ischemic stroke of rat

(2013) Syoichiro Kono et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mechanisms of Glutamate Transport

(2013) Robert J. Vandenberg et al.   PHYSIOLOGICAL REVIEWS

The inhibitor of volume-regulated anion channels DCPIB activates TREK potassium channels in cultured astrocytes

(2012) L Minieri et al.   BRITISH JOURNAL OF PHARMACOLOGY

TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation

(2012) Dong Ho Woo et al.   CELL

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

(2012) Carole Berthet et al.   CEREBROVASCULAR DISEASES

Effects of lactate on the voltage-gated sodium channels of rat skeletal muscle: modulating current opinion

(2012) F. Rannou et al.   JOURNAL OF APPLIED PHYSIOLOGY

Involvement of TREK-1 Activity in Astrocyte Function and Neuroprotection Under Simulated Ischemia Conditions

(2012) Xiao Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Distinct Expression/Function of Potassium and Chloride Channels Contributes to the Diverse Volume Regulation in Cortical Astrocytes of GFAP/EGFP Mice

(2012) Jana Benesova et al.   PLoS One

Brain Lactate Metabolism in Humans With Subarachnoid Hemorrhage

(2012) Mauro Oddo et al.   STROKE

Molecular regulations governing TREK and TRAAK channel functions

(2011) Jacques Noël et al.   Channels

Changes in Lipid-Sensitive Two-Pore Domain Potassium Channel TREK-1 Expression and Its Involvement in Astrogliosis Following Cerebral Ischemia in Rats

(2011) Minghuan Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Activation of TREK Currents by the Neuroprotective Agent Riluzole in Mouse Sympathetic Neurons

(2011) A. Cadaveira-Mosquera et al.   JOURNAL OF NEUROSCIENCE

Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate

(2011) J. E. Rinholm et al.   JOURNAL OF NEUROSCIENCE

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

(2011) Trent M Woodruff et al.   Molecular Neurodegeneration

Effect of intravenous administration of dipyridamole in a rat model of chronic cerebral ischemia

(2010) Alessia Melani et al.   Annals of the New York Academy of Sciences

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Lactateper seimproves the excitability of depolarized rat skeletal muscle by reducing the Cl−conductance

(2010) Frank Vincenzo de Paoli et al.   JOURNAL OF PHYSIOLOGY-LONDON

Impact of global cerebral ischemia on K+ channel expression and membrane properties of glial cells in the rat hippocampus

(2010) Helena Pivonkova et al.   NEUROCHEMISTRY INTERNATIONAL

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS

Channel-Mediated Tonic GABA Release from Glia

(2010) S. Lee et al.   SCIENCE

Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design

(2010) Jean Mazella et al.   PLOS BIOLOGY

Structural Features of Ischemic Damage in the Hippocampus

(2009) Alexander G. Nikonenko et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

TWIK-1 and TREK-1 Are Potassium Channels Contributing Significantly to Astrocyte Passive Conductance in Rat Hippocampal Slices

(2009) M. Zhou et al.   JOURNAL OF NEUROSCIENCE

Analysis of Astroglial K+ Channel Expression in the Developing Hippocampus Reveals a Predominant Role of the Kir4.1 Subunit

(2009) G. Seifert et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Human Two-Pore Domain K+ Channel TREK1 by Local Anesthetic Lidocaine: Negative Cooperativity and Half-of-Sites Saturation Kinetics

(2009) T. K. Nayak et al.   MOLECULAR PHARMACOLOGY

Overview of the Proton-coupled MCT (SLC16A) Family of Transporters: Characterization, Function and Role in the Transport of the Drug of Abuse γ-Hydroxybutyric Acid

(2008) Marilyn E. Morris et al.   AAPS Journal

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

(2008) Changlu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray Structures of Aerococcus viridans Lactate Oxidase and Its Complex with d-Lactate at pH 4.5 Show an α-Hydroxyacid Oxidation Mechanism

(2008) Makio Furuichi et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of Monocarboxylate Transporter 2 in the Retrotrapezoid Nucleus in Rats: A Test of the Astrocyte-Neuron Lactate-Shuttle Hypothesis

(2008) J. S. Erlichman et al.   JOURNAL OF NEUROSCIENCE

Ascorbic acid participates in a general mechanism for concerted glucose transport inhibition and lactate transport stimulation

(2008) Maite A. Castro et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY