标题
Mechanisms of Glutamate Transport
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 93, Issue 4, Pages 1621-1657
出版商
American Physiological Society
发表日期
2013-10-18
DOI
10.1152/physrev.00007.2013
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Allosteric Modulation of an Excitatory Amino Acid Transporter: The Subtype-Selective Inhibitor UCPH-101 Exerts Sustained Inhibition of EAAT1 through an Intramonomeric Site in the Trimerization Domain
- (2013) B. Abrahamsen et al. JOURNAL OF NEUROSCIENCE
- Protonation State of a Conserved Acidic Amino Acid Involved in Na+ Binding to the Glutamate Transporter EAAC1
- (2012) Juddy Mwaura et al. ACS Chemical Neuroscience
- Glutamate Transporter-Dependent mTOR Phosphorylation in Müller Glia Cells
- (2012) Ana María López-Colomé et al. ASN Neuro
- Mechanism of Inhibition of the Glutamate Transporter EAAC1 by the Conformationally Constrained Glutamate Analogue (+)-HIP-B
- (2012) Randolph Callender et al. BIOCHEMISTRY
- A point mutation associated with episodic ataxia 6 increases glutamate transporter anion currents
- (2012) Natalie Winter et al. BRAIN
- Conserved Asparagine Residue Located in Binding Pocket Controls Cation Selectivity and Substrate Interactions in Neuronal Glutamate Transporter
- (2012) Shlomit Teichman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neutralizing Aspartate 83 Modifies Substrate Translocation of Excitatory Amino Acid Transporter 3 (EAAT3) Glutamate Transporters
- (2012) Jasmin Hotzy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Rates of Postmortem Proteolysis of Glutamate Transporters Differ Dramatically between Cells and between Transporter Subtypes
- (2012) Yuchuan Li et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Structure–Activity Relationship Study of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101) and Absolute Configurational Assignment Using Infrared and Vibrational Circular Dichroism Spectroscopy in Combination with ab Initio Hartree–Fock Calculations
- (2012) Tri H. V. Huynh et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Density of EAAC1 (EAAT3) Glutamate Transporters Expressed by Neurons in the Mammalian CNS
- (2012) S. Holmseth et al. JOURNAL OF NEUROSCIENCE
- Structural Intermediates in a Model of the Substrate Translocation Path of the Bacterial Glutamate Transporter Homologue GltPh
- (2012) Sebastian Stolzenberg et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog
- (2012) Grégory Verdon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The glutamate transporter, GLAST, participates in a macromolecular complex that supports glutamate metabolism
- (2012) Deborah E. Bauer et al. NEUROCHEMISTRY INTERNATIONAL
- Synaptic Energy Use and Supply
- (2012) Julia J. Harris et al. NEURON
- Position of the Third Na+ Site in the Aspartate Transporter GltPh and the Human Glutamate Transporter, EAAT1
- (2012) Turgut Bastug et al. PLoS One
- Functional studies and rare variant screening of SLC1A1/EAAC1 in males with obsessive–compulsive disorder
- (2012) Jeremy Veenstra-VanderWeele et al. PSYCHIATRIC GENETICS
- Unique biology of gliomas: challenges and opportunities
- (2012) Stacey Watkins et al. TRENDS IN NEUROSCIENCES
- Effect of Inhibition of Spinal Cord Glutamate Transporters on Inflammatory Pain Induced by Formalin and Complete Freundʼs Adjuvant
- (2011) Myron Yaster et al. ANESTHESIOLOGY
- Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1
- (2011) Robert J. Vandenberg et al. BIOCHEMICAL JOURNAL
- Structure–activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators
- (2011) Xuechao Xing et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The Discovery of Slowness: Low-Capacity Transport and Slow Anion Channel Gating by the Glutamate Transporter EAAT5
- (2011) Armanda Gameiro et al. BIOPHYSICAL JOURNAL
- Free Energy Simulations of Ligand Binding to the Aspartate Transporter GltPh
- (2011) Germano Heinzelmann et al. BIOPHYSICAL JOURNAL
- Changes in glutamate transporter expression in mouse forebrain areas following focal ischemia
- (2011) Pirusha Ketheeswaranathan et al. BRAIN RESEARCH
- System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS
- (2011) Richard J Bridges et al. BRITISH JOURNAL OF PHARMACOLOGY
- Oncogene AEG-1 Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
- (2011) S.-G. Lee et al. CANCER RESEARCH
- Structure and mechanism of glutamate receptor ion channel assembly, activation and modulation
- (2011) Mark L Mayer CURRENT OPINION IN NEUROBIOLOGY
- A Conserved Aspartate Residue Located at the Extracellular End of the Binding Pocket Controls Cation Interactions in Brain Glutamate Transporters
- (2011) Noa Rosental et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Factor- B Contributes to Neuron-Dependent Induction of Glutamate Transporter-1 Expression in Astrocytes
- (2011) M. Ghosh et al. JOURNAL OF NEUROSCIENCE
- Co-compartmentalization of the Astroglial Glutamate Transporter, GLT-1, with Glycolytic Enzymes and Mitochondria
- (2011) E. N. Genda et al. JOURNAL OF NEUROSCIENCE
- Investigating the Mechanism of Substrate Uptake and Release in the Glutamate Transporter Homologue GltPh through Metadynamics Simulations
- (2011) Giovanni Grazioso et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- From glutamate co-release to vesicular synergy: vesicular glutamate transporters
- (2011) Salah El Mestikawy et al. NATURE REVIEWS NEUROSCIENCE
- Minimal Functional Sites Allow a Classification of Zinc Sites in Proteins
- (2011) Claudia Andreini et al. PLoS One
- The central cavity in trimeric glutamate transporters restricts ligand diffusion
- (2011) G. P. Leary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Large collective motions regulate the functional properties of glutamate transporter trimers
- (2011) J. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Na+:Aspartate Coupling Stoichiometry in the Glutamate Transporter Homologue GltPh
- (2010) Maarten Groeneveld et al. BIOCHEMISTRY
- Identification of the Third Na+ Site and the Sequence of Extracellular Binding Events in the Glutamate Transporter
- (2010) Zhijian Huang et al. BIOPHYSICAL JOURNAL
- Slips, leaks and channels in glutamate transporters
- (2010) Robert Vandenberg et al. Channels
- Astrocytes: Glutamate transport and alternate splicing of transporters
- (2010) Aven Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A Conserved Methionine Residue Controls the Substrate Selectivity of a Neuronal Glutamate Transporter
- (2010) Noa Rosental et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Conserved Aspartate Determines Pore Properties of Anion Channels Associated with Excitatory Amino Acid Transporter 4 (EAAT4)
- (2010) Peter Kovermann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hetero-oligomerization of Neuronal Glutamate Transporters
- (2010) Doreen Nothmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exon-skipping Splice Variants of Excitatory Amino Acid Transporter-2 (EAAT2) Form Heteromeric Complexes with Full-length EAAT2
- (2010) Florian M. Gebhardt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia Increases the Dependence of Glioma Cells on Glutathione
- (2010) Toyin Adeyemi Ogunrinu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism of Cation Binding to the Glutamate Transporter EAAC1 Probed with Mutation of the Conserved Amino Acid Residue Thr101
- (2010) Zhen Tao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria
- (2010) Charles G. Bailey et al. JOURNAL OF CLINICAL INVESTIGATION
- Structure−Activity Relationship Study of First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)
- (2010) Mette N. Erichsen et al. JOURNAL OF MEDICINAL CHEMISTRY
- The position of an arginine residue influences substrate affinity and K+ coupling in the human glutamate transporter, EAAT1
- (2010) Renae M. Ryan et al. JOURNAL OF NEUROCHEMISTRY
- The mechanism of substrate release by the aspartate transporter GltPh: insights from simulations
- (2010) Jason DeChancie et al. Molecular BioSystems
- New views of glutamate transporter structure and function: Advances and challenges
- (2010) Jie Jiang et al. NEUROPHARMACOLOGY
- Glutamate Receptor Ion Channels: Structure, Regulation, and Function
- (2010) S. F. Traynelis et al. PHARMACOLOGICAL REVIEWS
- The 3-4 loop of an archaeal glutamate transporter homolog experiences ligand-induced structural changes and is essential for transport
- (2010) E. L. R. Compton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model
- (2010) H. P. Larsson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural perspectives on secondary active transporters
- (2010) Olga Boudker et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- A family-based association study of the glutamate transporter geneSLC1A1in obsessive-compulsive disorder in 378 families
- (2009) Y.Y. Shugart et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Association of the Glutamate Transporter Gene SLC1A1 With Atypical Antipsychotics–Induced Obsessive-compulsive Symptoms
- (2009) Jun Soo Kwon et al. ARCHIVES OF GENERAL PSYCHIATRY
- A Haplotype Containing Quantitative Trait Loci for SLC1A1 Gene Expression and Its Association With Obsessive-Compulsive Disorder
- (2009) Jens R. Wendland et al. ARCHIVES OF GENERAL PSYCHIATRY
- Episodic Ataxia Associated With EAAT1 Mutation C186S Affecting Glutamate Reuptake
- (2009) Boukje de Vries et al. ARCHIVES OF NEUROLOGY
- Functional Characterization of a Na+-dependent Aspartate Transporter fromPyrococcus horikoshii
- (2009) Renae M. Ryan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of the First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1
- (2009) Anders A. Jensen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Glutamate Transporter Coupling to Na,K-ATPase
- (2009) E. M. Rose et al. JOURNAL OF NEUROSCIENCE
- Close Encounters of the Oily Kind: Regulation of Transporters by Lipids
- (2009) C. B. Divito et al. MOLECULAR INTERVENTIONS
- The Four Major N- and C-Terminal Splice Variants of the Excitatory Amino Acid Transporter GLT-1 Form Cell Surface Homomeric and Heteromeric Assemblies
- (2009) E. Peacey et al. MOLECULAR PHARMACOLOGY
- Transport mechanism of a bacterial homologue of glutamate transporters
- (2009) Nicolas Reyes et al. NATURE
- The concentrations and distributions of three C-terminal variants of the GLT1 (EAAT2; slc1a2) glutamate transporter protein in rat brain tissue suggest differential regulation
- (2009) S. Holmseth et al. NEUROSCIENCE
- Water transport between CNS compartments: contributions of aquaporins and cotransporters
- (2009) N. MacAulay et al. NEUROSCIENCE
- Behavioral characterization of GLT1 (+/-) mice as a model of mild glutamatergic hyperfunction
- (2009) Anna Kiryk et al. NEUROTOXICITY RESEARCH
- The equivalent of a thallium binding residue from an archeal homolog controls cation interactions in brain glutamate transporters
- (2009) S. Teichman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats
- (2009) T. J. Crisman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thallium Ions Can Replace both Sodium and Potassium Ions in the Glutamate Transporter Excitatory Amino Acid Carrier 1†
- (2008) Zhen Tao et al. BIOCHEMISTRY
- Dynamics of the Extracellular Gate and Ion-Substrate Coupling in the Glutamate Transporter
- (2008) Zhijian Huang et al. BIOPHYSICAL JOURNAL
- Glutamate transporter blockers for elucidation of the function of excitatory neurotransmission systems
- (2008) Keiko Shimamoto CHEMICAL RECORD
- Glutamate-induced glioma cell proliferation is prevented by functional expression of the glutamate transporter GLT-1
- (2008) Nicolas Vanhoutte et al. FEBS LETTERS
- Substrates and Non-transportable Analogues Induce Structural Rearrangements at the Extracellular Entrance of the Glial Glutamate Transporter GLT-1/EAAT2
- (2008) Shaogang Qu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Time-resolved Mechanism of Extracellular Gate Opening and Substrate Binding in a Glutamate Transporter
- (2008) Indira H. Shrivastava et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of Cation Binding in Determining Substrate Selectivity of Glutamate Transporters
- (2008) Shiwei Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes
- (2008) Seok-Geun Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation
- (2008) S. Maier et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1
- (2008) Amanda L. Sheldon et al. NEUROCHEMISTRY INTERNATIONAL
- A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)
- (2008) D.N. Furness et al. NEUROSCIENCE
- Interactions of alkali cations with glutamate transporters
- (2008) D. C Holley et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Amino Acid Transport Across Mammalian Intestinal and Renal Epithelia
- (2008) Stefan Bröer PHYSIOLOGICAL REVIEWS
- A β-Lactam Antibiotic Dampens Excitotoxic Inflammatory CNS Damage in a Mouse Model of Multiple Sclerosis
- (2008) Nico Melzer et al. PLoS One
- Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1
- (2007) Elena Fumagalli et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Transporters for L-glutamate: An update on their molecular pharmacology and pathological involvement
- (2006) P M Beart et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effects of threo-β-hydroxyaspartate derivatives on excitatory amino acid transporters (EAAT4 and EAAT5)
- (2003) Yasushi Shigeri et al. JOURNAL OF NEUROCHEMISTRY
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