Genetic association studies in drug-induced liver injury

Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent

(2011) Jing Yuan et al.   AIDS

A Fresh Look at the Mechanism of Isoniazid-Induced Hepatotoxicity

(2011) I G Metushi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer

(2011) Colin F. Spraggs et al.   JOURNAL OF CLINICAL ONCOLOGY

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan

(2011) Pei Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Delayed drug hypersensitivity: models of T-cell stimulation

(2010) Jacqueline Adam et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury

(2010) M. Isabel Lucena et al.   HEPATOLOGY

Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop

(2010) Robert J. Fontana et al.   HEPATOLOGY

A role for the pregnane X receptor in flucloxacillin-induced liver injury

(2010) Elise Andrews et al.   HEPATOLOGY

Polymerase γ Gene POLG determines the risk of sodium valproate-induced liver toxicity

(2010) Joanna D. Stewart et al.   HEPATOLOGY

Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

(2010) Takeshi Ozeki et al.   HUMAN MOLECULAR GENETICS

Novel genomic techniques open new avenues in the analysis of monogenic disorders

(2010) Gregor Kuhlenbäumer et al.   HUMAN MUTATION

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

(2010) Peter T. Donaldson et al.   JOURNAL OF HEPATOLOGY

Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma

(2010) Chun-Fang Xu et al.   JOURNAL OF HEPATOLOGY

Influence of glutathione S-transferase M1 and T1 homozygous null mutations on the risk of antituberculosis drug-induced hepatotoxicity in a Caucasian population

(2010) Virginia Leiro et al.   LIVER INTERNATIONAL

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

HLA: a pharmacogenomics success story

(2010) Laurent Becquemont   PHARMACOGENOMICS

Drug-Induced Liver Injury Network (DILIN) Prospective Study

(2009) Robert J. Fontana et al.   DRUG SAFETY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis

(2009) Sang-Heon Kim et al.   PHARMACOGENOMICS

Genetic variations ofNAT2andCYP2E1and isoniazid hepatotoxicity in a diverse population

(2009) So Yamada et al.   PHARMACOGENOMICS

Immunoallergic Drug-Induced Liver Injury in Humans

(2009) Jack Uetrecht   SEMINARS IN LIVER DISEASE

The Natural History of Drug-Induced Liver Injury

(2009) Einar Björnsson   SEMINARS IN LIVER DISEASE

Association of slow N-acetyltransferase 2 profile and anti-TB drug-induced hepatotoxicity in patients from Southern Brazil

(2008) L. G. Possuelo et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

GlutathioneS-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury

(2008) M. Isabel Lucena et al.   HEPATOLOGY

Analysis of IL-10, IL-4 and TNF-α polymorphisms in drug-induced liver injury (DILI) and its outcome

(2008) Ketevan Pachkoria et al.   JOURNAL OF HEPATOLOGY

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic variants of hepatic transporters and susceptibility to drug induced liver injury

(2008) Pallav Bhatnagar et al.   TOXICOLOGY