Mutations in IRGM Are Associated With More Frequent Need for Surgery in Patients With Ileocolonic Crohnʼs Disease

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Population-Specific Susceptibility to Crohn's Disease and Ulcerative Colitis; Dominant and Recessive Relative Risks in the Japanese Population

(2010) Shigeki Nakagome et al.   ANNALS OF HUMAN GENETICS

Crohnʼs disease activity index does not correlate with endoscopic recurrence one year after ileocolonic resection

(2010) Miguel Regueiro et al.   INFLAMMATORY BOWEL DISEASES

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Confirmation of Multiple Crohn's Disease Susceptibility Loci in a Large Dutch–Belgian Cohort

(2009) Rinse K Weersma et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Update on genetics in inflammatory disease

(2009) Casper G. Noomen et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Faecal calprotectin or lactoferrin can identify postoperative recurrence in Crohn's disease

(2009) C. A. Lamb et al.   BRITISH JOURNAL OF SURGERY

Severity of postoperative recurrence in crohnʼs disease: Correlation between endoscopic and sonographic findings

(2009) Emma Calabrese et al.   INFLAMMATORY BOWEL DISEASES

Characterization of single-nucleotide polymorphisms relevant to inflammatory bowel disease in commonly used gastrointestinal cell lines

(2009) Claudia Huebner et al.   INFLAMMATORY BOWEL DISEASES

Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

(2009) Mark S Silverberg et al.   NATURE GENETICS

Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history

(2009) Charlie W Lees et al.   Expert Review of Gastroenterology & Hepatology

Polymorphism of the IRGM Gene Might Predispose to Fistulizing Behavior in Crohn's Disease

(2008) A Latiano et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Anastomotic recurrence of Crohn’s disease after ileocolic resection: comparison of MR enteroclysis with endoscopy

(2008) Johannes Sailer et al.   EUROPEAN RADIOLOGY

Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort

(2008) R L Roberts et al.   GENES AND IMMUNITY

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

(2008) Andre Franke et al.   NATURE GENETICS

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

(2008) Sheila A Fisher et al.   NATURE GENETICS

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

(2008) Andre Franke et al.   NATURE GENETICS

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

SNPping away at the pathogenesis of Crohnʼs disease

(2007) Alan Huett et al.   INFLAMMATORY BOWEL DISEASES

New links to the pathogenesis of Crohn disease provided by genome-wide association scans

(2007) Christopher G. Mathew   NATURE REVIEWS GENETICS