Targeting Apoptosis in Autoimmune Hepatitis

Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targets

(2014) A. J. Czaja   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Review article: the prevention and reversal of hepatic fibrosis in autoimmune hepatitis

(2014) A. J. Czaja   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Diversity and characterization of polymorphic 5′ promoter haplotypes of MICA and MICB genes

(2014) S. T. Cox et al.   TISSUE ANTIGENS

Hepatic inflammation and progressive liver fibrosis in chronic liver disease

(2014) Albert J Czaja   WORLD JOURNAL OF GASTROENTEROLOGY

Inhibitor of apoptosis proteins (IAPs) as regulatory factors of hepatic apoptosis

(2013) Kewei Wang et al.   CELLULAR SIGNALLING

JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells

(2013) Valerio Giacomo Minero et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Assembly of the Bak Apoptotic Pore

(2013) Stephen Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14·TRAIL

(2013) Hodaya Prinz-Hadad et al.   Journal of Neuroinflammation

Human intrahepatic biliary epithelial cells engulf blebs from their apoptotic peers

(2012) G.-H. Rong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Liver Restores Immune Homeostasis after Local Inflammation despite the Presence of Autoreactive T Cells

(2012) Kathie Béland et al.   PLoS One

c-FLIP Maintains Tissue Homeostasis by Preventing Apoptosis and Programmed Necrosis

(2012) X. Piao et al.   Science Signaling

Low doses of the novel caspase-inhibitor GS-9450 leads to lower caspase-3 and -8 expression on peripheral CD4+ and CD8+ T-cells

(2011) J. E. Arends et al.   APOPTOSIS

Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes

(2011) Bettina A. Mayer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis

(2011) Guanghua Rong et al.   HEPATOLOGY

Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis

(2011) A Mühlethaler-Mottet et al.   Cell Death & Disease

TAM receptors and the clearance of apoptotic cells

(2010) Greg Lemke et al.   Annals of the New York Academy of Sciences

Activation and Specificity of Human Caspase-10

(2010) Katherine Wachmann et al.   BIOCHEMISTRY

Autoimmunity and the Clearance of Dead Cells

(2010) Shigekazu Nagata et al.   CELL

Short interfering RNA targetting NF-kappa B induces apoptosis of hepatic stellate cells and attenuates extracellular matrix production

(2010) Donglai Cui et al.   DIGESTIVE AND LIVER DISEASE

Apoptosis in Immune-Mediated Liver Diseases

(2010) Alisan Kahraman et al.   DIGESTIVE DISEASES

Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

(2010) Ana Lleo et al.   HEPATOLOGY

Diagnosis and management of autoimmune hepatitis

(2010) Michael P. Manns et al.   HEPATOLOGY

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

(2010) Andrew Oberst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis

(2010) Quentin M. Anstee et al.   JOURNAL OF HEPATOLOGY

Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury

(2010) Lars P. Bechmann et al.   JOURNAL OF HEPATOLOGY

Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9

(2010) Petar S. Lenert   MEDIATORS OF INFLAMMATION

BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

(2010) D. Ren et al.   SCIENCE

Apoptosis as a Mechanism for Liver Disease Progression

(2010) Maria Eugenia Guicciardi et al.   SEMINARS IN LIVER DISEASE

Caspase Inhibitors for the Treatment of Hepatitis C

(2009) Howard C. Masuoka et al.   Clinics in Liver Disease

Apotopes and the biliary specificity of primary biliary cirrhosis

(2009) Ana Lleo et al.   HEPATOLOGY

Major histocompatibility complex class I-related chains A and B (MIC A/B): A novel role in nonalcoholic steatohepatitis

(2009) Alisan Kahraman et al.   HEPATOLOGY

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis

(2009) Rafal P. Witek et al.   HEPATOLOGY

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

Cellular FLICE-inhibitory protein (c-FLIP) signalling: A key regulator of receptor-mediated apoptosis in physiologic context and in cancer

(2009) Marina Bagnoli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Emerging roles of TLR7 and TLR9 in murine SLE

(2009) Marie-Laure Santiago-Raber et al.   JOURNAL OF AUTOIMMUNITY

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoantigens in systemic autoimmunity: critical partner in pathogenesis

(2009) A. Rosen et al.   JOURNAL OF INTERNAL MEDICINE

XIAP discriminates between type I and type II FAS-induced apoptosis

(2009) Philipp J. Jost et al.   NATURE

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Optimisation of circulating biomarkers of cell death for routine clinical use

(2008) A. Greystoke et al.   ANNALS OF ONCOLOGY

Serum levels of soluble major histocompatibility complex (MHC) class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma

(2008) Keisuke Kohga et al.   CANCER SCIENCE

Peptides and Peptide Mimics as Modulators of Apoptotic Pathways

(2008) Mar Orzáez et al.   ChemMedChem

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Contextual Regulation of Inflammation: A Duet by Transforming Growth Factor-β and Interleukin-10

(2008) Ming O. Li et al.   IMMUNITY

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection

(2008) Martin Holdener et al.   JOURNAL OF EXPERIMENTAL MEDICINE