Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9

Suppressive Oligodeoxynucleotides Inhibit Silica-Induced Pulmonary Inflammation

(2014) T. Sato et al.   JOURNAL OF IMMUNOLOGY

Treatment with a Toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice

(2010) Kareem L. Graham et al.   AUTOIMMUNITY

Therapeutic Applications and Mechanisms Underlying the Activity of Immunosuppressive Oligonucleotides

(2009) Dennis M. Klinman et al.   Annals of the New York Academy of Sciences

Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells

(2009) Fernando E. Sepulveda et al.   IMMUNITY

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

(2009) D. H. Kono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Faslpr/lpr mice in vivo

(2009) Petar Lenert et al.   ARTHRITIS RESEARCH & THERAPY

The DNA Sugar Backbone 2′ Deoxyribose Determines Toll-like Receptor 9 Activation

(2008) Tobias Haas et al.   IMMUNITY

T Cell-Independent and Toll-like Receptor-Dependent Antigen-Driven Activation of Autoreactive B Cells

(2008) Robin A. Herlands et al.   IMMUNITY

TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium

(2008) Angela Trieu et al.   IMMUNOLOGY AND CELL BIOLOGY

Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis

(2008) George Plitas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

(2008) Cristiana Guiducci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity

(2007) Mirjam Peter et al.   IMMUNOLOGY