标题
Molecular mechanisms of diabetic cardiomyopathy
作者
关键词
Animal models, Autophagy, Cardiomyopathy, Diabetes, Fibrosis, Heart failure, Inflammation, Lipotoxicity, Metabolism, Review
出版物
DIABETOLOGIA
Volume 57, Issue 4, Pages 660-671
出版商
Springer Nature
发表日期
2014-01-29
DOI
10.1007/s00125-014-3171-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a
- (2013) Craig W. Younce et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy
- (2013) Zhong-Wei Liu et al. Cardiovascular Diabetology
- Diabetes and the Heart: Is There Objective Evidence of a Human Diabetic Cardiomyopathy?
- (2013) S. E. Litwin DIABETES
- Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice
- (2013) Karina Huynh et al. FREE RADICAL BIOLOGY AND MEDICINE
- Diabetes increases mortality after myocardial infarction by oxidizing CaMKII
- (2013) Min Luo et al. JOURNAL OF CLINICAL INVESTIGATION
- Insulin receptor substrate signaling suppresses neonatal autophagy in the heart
- (2013) Christian Riehle et al. JOURNAL OF CLINICAL INVESTIGATION
- Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms
- (2013) Tanner M. Fullmer et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
- (2013) Jeffrey R. Erickson et al. NATURE
- Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
- (2013) Jan-Wilhelm Kornfeld et al. NATURE
- Inducible Overexpression of GLUT1 Prevents Mitochondrial Dysfunction and Attenuates Structural Remodeling in Pressure Overload but Does Not Prevent Left Ventricular Dysfunction
- (2013) Renata O. Pereira et al. Journal of the American Heart Association
- Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy
- (2012) M. Rajesh et al. DIABETES
- Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity
- (2012) B. Zhou et al. DIABETOLOGIA
- The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: A differential role of unfolded protein response (UPR) signaling proteins
- (2012) Arun Prasath Lakshmanan et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Metabolic stress–induced activation of FoxO1 triggers diabetic cardiomyopathy in mice
- (2012) Pavan K. Battiprolu et al. JOURNAL OF CLINICAL INVESTIGATION
- Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1
- (2012) Prasanth Puthanveetil et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Genetic loss of insulin receptors worsens cardiac efficiency in diabetes
- (2012) Heiko Bugger et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice
- (2012) Amit Varma et al. PLoS One
- Diabetes Mellitus and Myocardial Mitochondrial Dysfunction
- (2012) Alexandra König et al. Heart Failure Clinics
- Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling
- (2012) Allyson L. Kranstuber et al. Frontiers in Physiology
- Autophagy anomalies in the diabetic myocardium
- (2011) Kimberley M. Mellor et al. Autophagy
- Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy
- (2011) Rodrigo Troncoso et al. CARDIOVASCULAR RESEARCH
- Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress
- (2011) Carlos I. Michel et al. Cell Metabolism
- Intravenous Gene Therapy With PIM-1 Via a Cardiotropic Viral Vector Halts the Progression of Diabetic Cardiomyopathy Through Promotion of Prosurvival Signaling
- (2011) Rajesh Katare et al. CIRCULATION RESEARCH
- TRB3 Gene Silencing Alleviates Diabetic Cardiomyopathy in a Type 2 Diabetic Rat Model
- (2011) Yun Ti et al. DIABETES
- Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice
- (2011) Z. Xie et al. DIABETES
- HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
- (2011) Omar Khan et al. IMMUNOLOGY AND CELL BIOLOGY
- Autophagy as a therapeutic target in cardiovascular disease
- (2011) Andriy Nemchenko et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice
- (2011) Kimberley M. Mellor et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus: Is It Really the First Marker of Diabetic Cardiomyopathy?
- (2011) Laura Ernande et al. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
- MicroRNAs 103 and 107 regulate insulin sensitivity
- (2011) Mirko Trajkovski et al. NATURE
- Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
- (2011) Sabine D. Jordan et al. NATURE CELL BIOLOGY
- Renal Failure Increases Cardiac Histone H3 Acetylation, Dimethylation, and Phosphorylation and the Induction of Cardiomyopathy-Related Genes in Type 2 Diabetes
- (2010) Anil Bhanudas Gaikwad et al. AMERICAN JOURNAL OF PATHOLOGY
- Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways
- (2010) Ethan J. Anderson et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondrial and Nuclear Cross Talk in Cell Death
- (2010) Shaida A. Andrabi et al. Annals of the New York Academy of Sciences
- Profound Cardioprotection With Chloramphenicol Succinate in the Swine Model of Myocardial Ischemia-Reperfusion Injury
- (2010) J. A. Sala-Mercado et al. CIRCULATION
- Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes
- (2010) Jianmin Li et al. DIABETES
- Autophagy in Hypertensive Heart Disease
- (2010) Zhao V. Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation
- (2010) Ni-Huiping Son et al. JOURNAL OF CLINICAL INVESTIGATION
- Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents
- (2010) Ippei Shimizu et al. JOURNAL OF CLINICAL INVESTIGATION
- Diabetes and incident heart failure in hypertensive and normotensive participants of the Strong Heart Study
- (2010) Giovanni de Simone et al. JOURNAL OF HYPERTENSION
- Isoform-selective HDAC inhibitors: Closing in on translational medicine for the heart
- (2010) Timothy A. McKinsey JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- 14-3-3 Protein Protects Against Cardiac Endoplasmic Reticulum Stress (ERS) and ERS-Initiated Apoptosis in Experimental Diabetes
- (2010) Flori R. Sari et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- MicroRNAs in Cardiovascular Diseases: Biology and Potential Clinical Applications
- (2010) Reena V. Kartha et al. Journal of Cardiovascular Translational Research
- Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH
- (2009) Sabrina Serpillon et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes
- (2009) S. Ares-Carrasco et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding
- (2009) Jordan J. Wright et al. CARDIOVASCULAR RESEARCH
- Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart
- (2009) Sihem Boudina et al. CIRCULATION
- Gene Deletion of the Kinin Receptor B1 Attenuates Cardiac Inflammation and Fibrosis During the Development of Experimental Diabetic Cardiomyopathy
- (2009) D. Westermann et al. DIABETES
- miR133a regulates cardiomyocyte hypertrophy in diabetes
- (2009) Biao Feng et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Rodent models of diabetic cardiomyopathy
- (2009) H. Bugger et al. Disease Models & Mechanisms
- Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction
- (2009) Stuart A. Cook et al. EUROPEAN HEART JOURNAL
- The Non-coding RNAgadd7Is a Regulator of Lipid-induced Oxidative and Endoplasmic Reticulum Stress
- (2009) Rita T. Brookheart et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy
- (2009) Mohanraj Rajesh et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Diabetes- and angiotensin II-induced cardiac endoplasmic reticulum stress and cell death: metallothionein protection
- (2009) Jiancheng Xu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart
- (2009) Ethan J. Anderson et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Multiple roles of HDAC inhibition in neurodegenerative conditions
- (2009) De-Maw Chuang et al. TRENDS IN NEUROSCIENCES
- Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy
- (2008) Sophie Linthout et al. BASIC RESEARCH IN CARDIOLOGY
- Autophagy in Load-Induced Heart Disease
- (2008) Beverly A. Rothermel et al. CIRCULATION RESEARCH
- miR-133 and miR-30 Regulate Connective Tissue Growth Factor
- (2008) Rudy F. Duisters et al. CIRCULATION RESEARCH
- Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome
- (2008) Heiko Bugger et al. CLINICAL SCIENCE
- Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3
- (2008) H. Bugger et al. DIABETES
- Intracellular Angiotensin II Production in Diabetic Rats Is Correlated With Cardiomyocyte Apoptosis, Oxidative Stress, and Cardiac Fibrosis
- (2008) V. P. Singh et al. DIABETES
- Superoxide and Respiratory Coupling in Mitochondria of Insulin-Deficient Diabetic Rats
- (2008) Judith A. Herlein et al. ENDOCRINOLOGY
- Most mammalian mRNAs are conserved targets of microRNAs
- (2008) R. C. Friedman et al. GENOME RESEARCH
- Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy
- (2008) Heng Ma et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PARP mediates structural alterations in diabetic cardiomyopathy
- (2008) Jane Chiu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus
- (2008) Luuk J. Rijzewijk et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
- (2008) J.-F. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started