Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission

(2011) Beth Y Besecker et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Abundant Pleiotropy in Human Complex Diseases and Traits

(2011) Shanya Sivakumaran et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey

(2011) Pia Pajunen et al.   BMC PUBLIC HEALTH

Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

(2011) V. Lyssenko et al.   DIABETES

Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals

(2011) K. S. Burgdorf et al.   DIABETOLOGIA

Cohort Profile: Updating the cohort profile for the MRC National Survey of Health and Development: a new clinic-based data collection for ageing research

(2011) D. Kuh et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

MTCH2 in Human White Adipose Tissue and Obesity

(2011) Agné Kulyté et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Key contribution of CPEB4-mediated translational control to cancer progression

(2011) Elena Ortiz-Zapater et al.   NATURE MEDICINE

The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

(2011) Günter P. Wagner et al.   NATURE REVIEWS GENETICS

Association between birth weight and visceral fat in adults

(2010) Emanuella De Lucia Rolfe et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Obesity-Related Hypertension: Epidemiology, Pathophysiology, and Clinical Management

(2010) Theodore A. Kotchen   AMERICAN JOURNAL OF HYPERTENSION

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

(2010) Dawn M. Waterworth et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Randomised controlled trial of the effects of physical activity feedback on awareness and behaviourin UK adults: the FAB study protocol [ISRCTN92551397]

(2010) Clare Watkinson et al.   BMC PUBLIC HEALTH

Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans

(2010) E. Ingelsson et al.   DIABETES

Effects of a lifestyle intervention in metabolically benign and malign obesity

(2010) K. Kantartzis et al.   DIABETOLOGIA

Metabolically healthy obesity: different prevalences using different criteria

(2010) S Velho et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Open questions about metabolically normal obesity

(2010) Z Pataky et al.   INTERNATIONAL JOURNAL OF OBESITY

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

(2010) Richa Saxena et al.   NATURE GENETICS

Polymorphism in the CETP Gene Region, HDL Cholesterol, and Risk of Future Myocardial Infarction

(2009) Paul M. Ridker et al.   Circulation-Cardiovascular Genetics

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Molecular Determinants of Grb14-Mediated Inhibition of Insulin Signaling

(2009) Diana Goenaga et al.   MOLECULAR ENDOCRINOLOGY

The genetics of quantitative traits: challenges and prospects

(2009) Trudy F. C. Mackay et al.   NATURE REVIEWS GENETICS

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2009) Cecilia M. Lindgren et al.   PLoS Genetics

Identification and Characterization of Metabolically Benign Obesity in Humans

(2008) Norbert Stefan   ARCHIVES OF INTERNAL MEDICINE

The Obese Without Cardiometabolic Risk Factor Clustering and the Normal Weight With Cardiometabolic Risk Factor Clustering

(2008) Rachel P. Wildman   ARCHIVES OF INTERNAL MEDICINE

Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI

(2008) R. M. Freathy et al.   DIABETES

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

General and Abdominal Adiposity and Risk of Death in Europe

(2008) T. Pischon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Obesity and cancer

(2008) Tobias Pischon et al.   PROCEEDINGS OF THE NUTRITION SOCIETY