Dicarbonyl Stress in the Absence of Hyperglycemia Increases Endothelial Inflammation and Atherogenesis Similar to That Observed in Diabetes

The Critical Role of Methylglyoxal and Glyoxalase 1 in Diabetic Nephropathy

(2013) N. Rabbani et al.   DIABETES

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype

(2013) Nordin M.J. Hanssen et al.   EUROPEAN HEART JOURNAL

Alagebrium Reduces Glomerular Fibrogenesis and Inflammation Beyond Preventing RAGE Activation in Diabetic Apolipoprotein E Knockout Mice

(2012) A. M. D. Watson et al.   DIABETES

Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates?

(2012) T. Fleming et al.   DIABETOLOGIA

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

(2012) Angelika Bierhaus et al.   NATURE MEDICINE

Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome

(2011) Jianghai Liu et al.   CARDIOVASCULAR RESEARCH

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes

(2011) N. Rabbani et al.   DIABETES

Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

(2011) A. K. Berner et al.   DIABETOLOGIA

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

(2010) A. G. Miller et al.   DIABETES

Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor

(2010) K. C. Sourris et al.   DIABETOLOGIA

Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice

(2010) A. M. D. Watson et al.   DIABETOLOGIA

Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats

(2010) Olaf Brouwers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAGE and the pathogenesis of chronic kidney disease

(2010) Vivette D'Agati et al.   Nature Reviews Nephrology

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance

(2010) Paul J. Thornalley et al.   NUCLEIC ACIDS RESEARCH

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

(2009) D. Yao et al.   DIABETES

Misconceptions about High-Fructose Corn Syrup: Is It Uniquely Responsible for Obesity, Reactive Dicarbonyl Compounds, and Advanced Glycation Endproducts?

(2009) John S. White   JOURNAL OF NUTRITION

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

(2008) A. Soro-Paavonen et al.   DIABETES

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE–/– mice

(2008) Evis Harja et al.   JOURNAL OF CLINICAL INVESTIGATION

Reactive dicarbonyl compounds and 5-(hydroxymethyl)-2-furfural in carbonated beverages containing high fructose corn syrup

(2007) C LO et al.   FOOD CHEMISTRY