Disposition of metformin: Variability due to polymorphisms of organic cation transporters

SLC22A2 gene 808 G/T variant is related to plasma lactate concentration in Chinese type 2 diabetics treated with metformin

(2010) Qing Li et al.   ACTA PHARMACOLOGICA SINICA

A Single Nucleotide Polymorphism in STK11 Influences Insulin Sensitivity and Metformin Efficacy in Hyperinsulinemic Girls With Androgen Excess

(2010) A. Lopez-Bermejo et al.   DIABETES CARE

Organic Cation Transporter 1 Polymorphisms Predict the Metabolic Response to Metformin in Women with the Polycystic Ovary Syndrome

(2010) Alessandra Gambineri et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic Polymorphisms in Organic Cation Transporter 1 (OCT1) in Chinese and Japanese Populations Exhibit Altered Function

(2010) L. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine

(2010) Zhi-Jun Wang et al.   Pharmacogenetics and Genomics

Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients

(2010) Kana Toyama et al.   Pharmacogenetics and Genomics

Current Understanding of the Pharmacogenomics of Metformin

(2009) O Zolk   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

(2009) M V Tzvetkov et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Reduced-Function SLC22A1 Polymorphisms Encoding Organic Cation Transporter 1 and Glycemic Response to Metformin: A GoDARTS Study

(2009) K. Zhou et al.   DIABETES

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

(2009) M. L. Becker et al.   DIABETES

Functional Characterization of the Human Organic Cation Transporter 2 Variant p.270Ala>Ser

(2009) O. Zolk et al.   DRUG METABOLISM AND DISPOSITION

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Targeted Disruption of the Multidrug and Toxin Extrusion 1 (Mate1) Gene in Mice Reduces Renal Secretion of Metformin

(2009) M. Tsuda et al.   MOLECULAR PHARMACOLOGY

Metformin Compared With Glyburide in Gestational Diabetes

(2009) Lisa E. Moore et al.   OBSTETRICS AND GYNECOLOGY

Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1

(2009) Ji Ha Choi et al.   Pharmacogenetics and Genomics

Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin

(2009) Ying Chen et al.   Pharmacogenetics and Genomics

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

(2009) M L Becker et al.   PHARMACOGENOMICS JOURNAL

Pharmacogenomics: Inter-ethnic and Intra-ethnic Differences in Pharmacokinetic and Pharmacodynamic Profiles of Clinically Relevant Drugs

(2009) Ichiro IEIRI et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Genetic Variants of the Organic Cation Transporter 2 Influence the Disposition of Metformin

(2008) IS Song et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mechanisms Underlying Saturable Intestinal Absorption of Metformin

(2008) W. R. Proctor et al.   DRUG METABOLISM AND DISPOSITION

Interindividual variability in oral antidiabetic drug disposition and response: the role of drug transporter polymorphisms

(2008) Michael A Pacanowski et al.   Expert Opinion on Drug Metabolism & Toxicology

Consensus on infertility treatment related to polycystic ovary syndrome

(2008)   HUMAN REPRODUCTION

Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2)

(2008) Oliver Zolk et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphism in human organic cation transporters and metformin action

(2008) Hiroshi Takane et al.   PHARMACOGENOMICS

Ovulatory Response to Treatment of Polycystic Ovary Syndrome Is Associated with a Polymorphism in theSTK11Gene

(2007) Richard S. Legro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM