Islet-1 Is Essential for Pancreatic  -Cell Function

LIM-homeodomain Transcription Factor Isl-1 Mediates the Effect of Leptin on Insulin Secretion in Mice

(2013) Juan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenomic plasticity enables human pancreatic α to β cell reprogramming

(2013) Nuria C. Bramswig et al.   JOURNAL OF CLINICAL INVESTIGATION

Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss

(2013) Crystal L. Wilcox et al.   PLoS One

Islet  -,  -, and  -Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

(2012) C. S. Hunter et al.   DIABETES

Elevation of transcription factor Islet-1 levels in vivo increases β-cell function but not β-cell mass

(2012) Jingxuan Liu et al.   Islets

Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx

(2011) Sangeeta Dhawan et al.   DEVELOPMENTAL CELL

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Islet-1 RegulatesArxTranscription during Pancreatic Islet α-Cell Development

(2011) Jingxuan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ISL1 Promotes Pancreatic Islet Cell Proliferation

(2011) Ting Guo et al.   PLoS One

MafA and MafB activity in pancreatic β cells

(2011) Yan Hang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Pancreatic β Cells Require NeuroD to Achieve and Maintain Functional Maturity

(2010) Chunyan Gu et al.   Cell Metabolism

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Calcineurin Signaling Regulates Human Islet β-Cell Survival

(2010) Scott A. Soleimanpour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rfx6 directs islet formation and insulin production in mice and humans

(2010) Stuart B. Smith et al.   NATURE

Tamoxifen-Independent Recombination in the RIP-CreER Mouse

(2010) Yanmei Liu et al.   PLoS One

Islet-1 is required for ventral neuron survival in Xenopus

(2009) Yu Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity

(2009) M.-R. Song et al.   DEVELOPMENT

Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

(2009) A. Du et al.   DIABETES

The LIM-Homeodomain Protein ISL1 Activates Insulin Gene Promoter Directly through Synergy with BETA2

(2009) Hui Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes

(2008) Mugdha Bhati et al.   EMBO JOURNAL

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

(2008) Yunfu Sun et al.   NATURE NEUROSCIENCE