Induction of Mixed Chimerism Depletes Pre-existing and De Novo–Developed Autoreactive B Cells in Autoimmune NOD Mice

B Lymphocyte Depletion by CD20 Monoclonal Antibody Prevents Diabetes in Nonobese Diabetic Mice despite Isotype-Specific Differences in Fc R Effector Functions

(2014) Y. Xiu et al.   JOURNAL OF IMMUNOLOGY

Therapeutic Targeting of B Cells and T Cells in Autoimmune Diabetes

(2013) Lucienne Chatenoud   DIABETES

Combination Treatment With Anti-CD20 and Oral Anti-CD3 Prevents and Reverses Autoimmune Diabetes

(2013) Changyun Hu et al.   DIABETES

B-Lymphocyte Depletion With Rituximab and  -Cell Function: Two-Year Results

(2013) M. D. Pescovitz et al.   DIABETES CARE

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

(2013) Natalia V. Giltiay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells

(2013) T. Wu et al.   JOURNAL OF IMMUNOLOGY

Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease

(2012) J. S. Young et al.   JOURNAL OF IMMUNOLOGY

Mixed Chimerism and Growth Factors Augment   Cell Regeneration and Reverse Late-Stage Type 1 Diabetes

(2012) M. Wang et al.   Science Translational Medicine

Induction of Mixed Chimerism With MHC-Mismatched but Not Matched Bone Marrow Transplants Results in Thymic Deletion of Host-Type Autoreactive T-Cells in NOD Mice

(2011) J. Racine et al.   DIABETES

Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies

(2011) David V. Serreze et al.   DIABETES

Loss of B7-H1 Expression by Recipient Parenchymal Cells Leads to Expansion of Infiltrating Donor CD8+ T Cells and Persistence of Graft-Versus-Host Disease

(2011) X. Li et al.   JOURNAL OF IMMUNOLOGY

Cellular Competition Independent of BAFF/B Lymphocyte Stimulator Results in Low Frequency of an Autoreactive Clonotype in Mature Polyclonal B Cell Compartments

(2011) N. Nikbakht et al.   JOURNAL OF IMMUNOLOGY

Type 1 Diabetes Immunotherapy: Is the Glass Half Empty or Half Full?

(2011) K. C. Herold et al.   Science Translational Medicine

Induction of Chimerism Permits Low-Dose Islet Grafts in the Liver or Pancreas to Reverse Refractory Autoimmune Diabetes

(2010) C. Zhang et al.   DIABETES

BAFF Receptor Signaling Aids the Differentiation of Immature B Cells into Transitional B Cells following Tonic BCR Signaling

(2010) S. L. Rowland et al.   JOURNAL OF IMMUNOLOGY

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

(2009) T. Yi et al.   BLOOD

Reduced Diabetes in btk-Deficient Nonobese Diabetic Mice and Restoration of Diabetes with Provision of an Anti-Insulin IgH Chain Transgene

(2009) P. L. Kendall et al.   JOURNAL OF IMMUNOLOGY

Absence of Mature Peripheral B Cell Populations in Mice with Concomitant Defects in B Cell Receptor and BAFF-R Signaling

(2009) K. L. Hoek et al.   JOURNAL OF IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI

(2008) N. Li et al.   BLOOD

In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease

(2008) D. Zhao et al.   BLOOD

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease

(2008) T. Yi et al.   BLOOD

Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes

(2008) P. Fiorina et al.   DIABETES

Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation

(2008) Almut Meyer-Bahlburg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen

(2008) N. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA