Roles of hypoxia, stem cells and epithelial-mesenchymal transition in the spread and treatment resistance of head and neck cancer

Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models

(2013) Sarah Elizabeth Wheeler et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Sub-Sets of Cancer Stem Cells Differ Intrinsically in Their Patterns of Oxygen Metabolism

(2013) Luke Gammon et al.   PLoS One

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

(2013) Vikash P. Chauhan et al.   Nature Communications

Metabolic reprogramming and two-compartment tumor metabolism

(2012) Barbara Chiavarina et al.   CELL CYCLE

Power Surge: Supporting Cells “Fuel” Cancer Cell Mitochondria

(2012) Ubaldo E. Martinez-Outschoorn et al.   Cell Metabolism

Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation

(2012) S.-w. Jing et al.   DISEASES OF THE ESOPHAGUS

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

(2012) S. J. Conley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer Stem Cells in Squamous Cell Carcinoma Switch between Two Distinct Phenotypes That Are Preferentially Migratory or Proliferative

(2011) A. Biddle et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma

(2011) Cheng-Chi Chang et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Activation of Hif1α by the Prolylhydroxylase Inhibitor Dimethyoxalyglycine Decreases Radiosensitivity

(2011) Marina K. Ayrapetov et al.   PLoS One

Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis

(2011) Jens Overgaard   RADIOTHERAPY AND ONCOLOGY

Cancer-related inflammation: Common themes and therapeutic opportunities

(2011) Frances R. Balkwill et al.   SEMINARS IN CANCER BIOLOGY

Reciprocal influence of the p53 and the hypoxic pathways

(2011) A Sermeus et al.   Cell Death & Disease

Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype

(2010) K Ameri et al.   BRITISH JOURNAL OF CANCER

Quiescent, Slow-Cycling Stem Cell Populations in Cancer: A Review of the Evidence and Discussion of Significance

(2010) Nathan Moore et al.   Journal of Oncology

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion

(2009) J Chen et al.   BRITISH JOURNAL OF CANCER

Small-Molecule Activation of p53 Blocks Hypoxia-Inducible Factor 1  and Vascular Endothelial Growth Factor Expression In Vivo and Leads to Tumor Cell Apoptosis in Normoxia and Hypoxia

(2009) J. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Mechanisms of c-Myc Degradation by Nickel Compounds and Hypoxia

(2009) Qin Li et al.   PLoS One

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration

(2008) G. Fitsialos et al.   JOURNAL OF CELL SCIENCE

Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity

(2008) R. Sullivan et al.   MOLECULAR CANCER THERAPEUTICS

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY