Constructing manmade enzymes for oxygen activation

The monooxygenase, peroxidase, and peroxygenase properties of cytochrome P450

(2012) Eugene G. Hrycay et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Engineering oxidoreductases: maquette proteins designed from scratch

(2012) Bruce R. Lichtenstein et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

FRED and HYBRID docking performance on standardized datasets

(2012) Mark McGann   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Domain-Swapped Dimeric Structure of a Stable and Functional De Novo Four-Helix Bundle Protein, WA20

(2012) Ryoichi Arai et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Squaring the Circle in Peptide Assembly: From Fibers to Discrete Nanostructures by de Novo Design

(2012) Aimee L. Boyle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic functionalization of unactivated primary C–H bonds directed by an alcohol

(2012) Eric M. Simmons et al.   NATURE

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

(2012) Sagar D Khare et al.   Nature Chemical Biology

Adding Aliphatic C-H Bond Oxidations to Synthesis

(2012) M. C. White   SCIENCE

Proteins from an Unevolved Library of de novo Designed Sequences Bind a Range of Small Molecules

(2012) Izhack Cherny et al.   ACS Synthetic Biology

A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology

(2012) Jordan M. Fletcher et al.   ACS Synthetic Biology

Dioxygen Activation in Soluble Methane Monooxygenase

(2011) Christine E. Tinberg et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Heme Peroxidase with a Functional Role as anl-Tyrosine Hydroxylase in the Biosynthesis of Anthramycin

(2011) Katherine L. Connor et al.   BIOCHEMISTRY

SCORER 2.0: an algorithm for distinguishing parallel dimeric and trimeric coiled-coil sequences

(2011) C. T. Armstrong et al.   BIOINFORMATICS

Cytochromes P450 as useful biocatalysts: addressing the limitations

(2011) Elaine O'Reilly et al.   CHEMICAL COMMUNICATIONS

Fundamentals of green chemistry: efficiency in reaction design

(2011) Roger A. Sheldon   CHEMICAL SOCIETY REVIEWS

Cytochrome P450: taming a wild type enzyme

(2011) Sang Taek Jung et al.   CURRENT OPINION IN BIOTECHNOLOGY

Enzymatic reductions for the chemist

(2011) Frank Hollmann et al.   GREEN CHEMISTRY

Characterization of SfmD as a Heme Peroxidase That Catalyzes the Regioselective Hydroxylation of 3-Methyltyrosine to 3-Hydroxy-5-methyltyrosine in Saframycin A Biosynthesis

(2011) Man-Cheng Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution

(2011) Olga Khersonsky et al.   JOURNAL OF MOLECULAR BIOLOGY

A de novo peptide hexamer with a mutable channel

(2011) Nathan R Zaccai et al.   Nature Chemical Biology

Hydrolytic catalysis and structural stabilization in a designed metalloprotein

(2011) Melissa L. Zastrow et al.   Nature Chemistry

Oxidation Reactions Performed by Soluble Methane Monooxygenase Hydroxylase Intermediates Hperoxoand Q Proceed by Distinct Mechanisms

(2010) Christine E. Tinberg et al.   BIOCHEMISTRY

Biocatalytic Redox Reactions for Organic Synthesis: Nonconventional Regeneration Methods

(2010) Frank Hollmann et al.   ChemCatChem

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Generation of Human Chiral Metabolites of Simvastatin and Lovastatin by Bacterial CYP102A1 Mutants

(2010) K.-H. Kim et al.   DRUG METABOLISM AND DISPOSITION

Enzyme-mediated oxidations for the chemist

(2010) Frank Hollmann et al.   GREEN CHEMISTRY

The Evolution and Structure Prediction of Coiled Coils across All Genomes

(2010) Owen J.L. Rackham et al.   JOURNAL OF MOLECULAR BIOLOGY

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

(2010) J. B. Siegel et al.   SCIENCE

Rational design of peptide-based building blocks for nanoscience and synthetic biology

(2009) Craig T. Armstrong et al.   FARADAY DISCUSSIONS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin production

(2009) Kian-Sim Goo et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Structural Analysis of Metal Sites in Proteins: Non-heme Iron Sites as a Case Study

(2009) Claudia Andreini et al.   JOURNAL OF MOLECULAR BIOLOGY

Design and engineering of an O2 transport protein

(2009) Ronald L. Koder et al.   NATURE

Design of protein-interaction specificity gives selective bZIP-binding peptides

(2009) Gevorg Grigoryan et al.   NATURE

An artificial di-iron oxo-protein with phenol oxidase activity

(2009) Marina Faiella et al.   Nature Chemical Biology

The role of position a in determining the stability and oligomerization state of α-helical coiled coils: 20 amino acid stability coefficients in the hydrophobic core of proteins

(2009) Kurt Wagschal et al.   PROTEIN SCIENCE

Cofactor binding and enzymatic activity in an unevolved superfamily ofde novodesigned 4-helix bundle proteins

(2009) Shona C. Patel et al.   PROTEIN SCIENCE

Catalytic effectiveness, a measure of enzyme proficiency for industrial applications

(2009) Richard J. Fox et al.   TRENDS IN BIOTECHNOLOGY

Predicting Protein Ligand Binding Sites by Combining Evolutionary Sequence Conservation and 3D Structure

(2009) John A. Capra et al.   PLoS Computational Biology

Protein and Electrode Engineering for the Covalent Immobilization of P450 BMP on Gold

(2008) Valentina E. V. Ferrero et al.   ANALYTICAL CHEMISTRY

Biocatalysts for selective introduction of oxygen

(2008) David J. Leak et al.   BIOCATALYSIS AND BIOTRANSFORMATION

Controlling complexity and water penetration in functionalde novoprotein design

(2008) J.L. Ross Anderson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Designed α-Helical Tectons for Constructing Multicomponent Synthetic Biological Systems

(2008) Elizabeth H. C. Bromley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

Expanding chemical biology of 2-oxoglutarate oxygenases

(2008) Christoph Loenarz et al.   Nature Chemical Biology

CC+: a relational database of coiled-coil structures

(2008) O. D. Testa et al.   NUCLEIC ACIDS RESEARCH

Green chemistry for chemical synthesis

(2008) C.-J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric constraints for porphyrin binding in helical protein binding sites

(2008) Christopher Negron et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS