Engineering oxidoreductases: maquette proteins designed from scratch

Control of Substrate Specificity by a Single Active Site Residue of the KsgA Methyltransferase

(2011) Heather C. O’Farrell et al.   BIOCHEMISTRY

Directed Evolution of a Gatekeeper Domain in Nonribosomal Peptide Synthesis

(2011) Benoit Villiers et al.   CHEMISTRY & BIOLOGY

Markovian and Non-Markovian Protein Sequence Evolution: Aggregated Markov Process Models

(2011) Carolin Kosiol et al.   JOURNAL OF MOLECULAR BIOLOGY

Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope

(2011) Mihai L. Azoitei et al.   JOURNAL OF MOLECULAR BIOLOGY

De Novo Enzyme Design Using Rosetta3

(2011) Florian Richter et al.   PLoS One

Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase

(2011) P. O'Donoghue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of a switchable eliminase

(2011) I. V. Korendovych et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme

(2011) Sylvia H-C. Yip et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Role of Asparagine 510 in the Relative Timing of Substrate Bond Cleavages in the Reaction Catalyzed by Choline Oxidase

(2010) Kunchala Rungsrisuriyachai et al.   BIOCHEMISTRY

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

(2010) J. B. Siegel et al.   SCIENCE

Mutagenesis Alters the Catalytic Mechanism of the Light-driven Enzyme Protochlorophyllide Oxidoreductase

(2009) Binuraj R. K. Menon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design and engineering of an O2 transport protein

(2009) Ronald L. Koder et al.   NATURE

Controlling complexity and water penetration in functionalde novoprotein design

(2008) J.L. Ross Anderson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE