Review
Chemistry, Multidisciplinary
Jiahao Wang, Xinxin Lv, Zhiyong Jiang
Summary: Asymmetric catalysis is a powerful tool for synthesizing enantioenriched molecules. Deracemization, the direct conversion of a racemic compound to one enantiomer, is an attractive approach with high-atom efficiency. Visible-light-driven photocatalysis has recently emerged as a promising platform for deracemization, overcoming kinetic and thermodynamic challenges in chemical transformations without the need for additional stoichiometric reagents. This review systematically summarizes and discusses the advances in this area, categorizing examples based on energy transfer and single-electron transfer in photocatalysis.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Kai Diao, Daniel J. Whitaker, Zehuan Huang, Hongwei Qian, Dongxing Ren, Liangliang Zhang, Zheng-Yi Li, Xiao-Qiang Sun, Tangxin Xiao, Leyong Wang
Summary: Researchers have successfully developed a novel material that can self-assemble into dispersed nanoparticles in water and achieve efficient white-light emission through a light-harvesting strategy. By co-assembling with cyanostilbene, the material shows potential for application in white-light encryption materials.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Ricardo I. Rodriguez, Leonardo Mollari, Jose Aleman
Summary: This study introduces a light-driven, atom-economical process for synthesizing enantiomerically enriched substituted chiral 1-pyrroline derivatives through distal functionalization of acyl heterocycles and the use of tailor-made ketimines as partners. Water is the sole by-product of the reaction, and stereoselectivity is controlled by coordination to a chiral-at-rhodium catalyst.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Nikolaos Vagkidis, Lijuan Li, Jennifer M. Marsh, Victor Chechik
Summary: Degradation of peptides and proteins by UV light is enhanced by subsequent heating, with the formation of hydroperoxide intermediates playing a key role. This process is particularly relevant for dead biological tissues like human hair, which are exposed to alternating UV and heat treatments. Through experiments using protected peptides as protein mimics, the synergistic action of UV light and heat treatment was confirmed. Analytical techniques including mass spectrometry and isotope exchange experiments were used to detect and quantify hydroperoxide intermediates formed upon UV exposure, and their role in peptide degradation was further confirmed by treatment with NaBH4.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Polyssena Renzi, Emanuele Azzi, Sylvain Ascensio, Stefano Parisotto, Fabrizio Sordello, Francesco Pellegrino, Giovanni Ghigo, Annamaria Deagostino
Summary: This paper explores the potential of diarylmethylium tetrafluoroborates as catalysts for the visible light promoted hydrosulfonylation of unactivated alkenes. These bench stable and easily preparable salts were used as organocatalysts for the first time, with a catalyst loading of just 1 mol% resulting in efficient sulfone product formation. Experimental and computational studies revealed a new mechanism for the formation of the key sulfonyl radical, with the photoactive species being proven to be stable S-C adducts and ion couples, rather than the diarylcarbenium salt itself. The mechanism involves charge-transfer excited states and proton-coupled electron transfer reactions.
Article
Engineering, Environmental
Mengqiao Li, Dairong Liu, Xing Chen, Zhihong Yin, Hongchen Shen, Ashlee Aiello, Kevin R. McKenzie, Nan Jiang, Xue Li, Michael J. Wagner, David P. Durkin, Hanning Chen, Danmeng Shuai
Summary: This research demonstrates that the presence of photoinduced holes (h(+)) on g-C3N4 nanosheets can significantly enhance the decomposition of nanomaterials under (OH)-O-center dot attack. The study highlights the importance of understanding the environmental transformation of emerging photoreactive nanomaterials and provides guidelines for designing robust nanomaterials for engineering applications.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Polymer Science
Lorand Bonda, Daniel J. J. Valles, Tillmann L. L. Wigger, Jan Meisner, Adam B. B. Braunschweig, Laura Hartmann
Summary: Controlled radical polymerizations (CRPs) are an important method for obtaining uniform and defined molecular weight polymers with complex composition and architecture. A new controlled and light-initiated radical polymerization using thiol initiators and an Ir-photocatalyst is introduced. Different reaction parameters are studied for their importance in achieving controlled characteristics of polymerization, such as low dispersity and control of molecular weights, and the ability to access block copolymers easily. The proposed mechanism for thiol-induced, light-activated, controlled radical polymerization (TIRP) involves the formation of dormant species and their equilibrium with the active polymer chain end, which is dependent on light and catalyst. TIRP expands the range of controlled and light-initiated polymerization methods by its mild conditions and the ability to grow polymers from a variety of readily available thiols.
Article
Chemistry, Organic
Zhaoming Hu, Yanzhao Wang, Kaiji Wang, Jingjing Wu, Fanhong Wu
Summary: In this report, we introduce a new strategy for the synthesis of difluorothiocyanate compounds through visible-light-induced, copper-catalyzed three-component thiocyanation of alkenes. This approach is versatile and can be extended to perfluorothiocyanate compounds and even complex molecules with drug/natural product skeletons. Mechanistic studies reveal that the copper complex plays a dual role as a photoredox catalyst for electron transfer and a cross-coupling catalyst for C-SCN bond formation.
Article
Multidisciplinary Sciences
Qinglong Shi, Meichen Xu, Rui Chang, Devenderan Ramanathan, Beatriz Penin, Ignacio Funes-Ardoiz, Juntao Ye
Summary: A metal-free platform using peptide- or sugar-derived chiral thiols and deuterium oxide enables asymmetric open-shell deuteration at non-benzylic positions. This approach allows for multiple types of deuterofunctionalization reactions of exocyclic olefins and achieves high levels of enantioselectivity and deuterium incorporation.
NATURE COMMUNICATIONS
(2022)
Article
Polymer Science
Shuo Zhang, Yichuan Zhang, Muhammed Ucuncu, Annamaria Lilienkampf, Jin Geng, Mark Bradley
Summary: The PET-RAFT polymerization method allows controlled synthesis of polymers using photoinduced electron transfer, providing an alternative to transition metal-based photoinitiators. Through the synthesis of fluorophore-conjugated RAFT agents, light-controlled polymerization has been achieved, yielding polymers with a single fluorophore per chain and allowing for the formation of fluorescently labelled and block copolymers.
Article
Chemistry, Physical
Han Yu, Tangyu Zhan, Yuqiao Zhou, Long Chen, Xiaohua Liu, Xiaoming Feng
Summary: Enantioselective photoreduction of ketones with hydrocarbons is a promising method for the synthesis of chiral tertiary alcohols. However, the current approach using ultraviolet light suffers from competitive reactions. In this study, a combined system involving chiral Lewis acid catalysis, photoredox catalysis, and hydrogen atom transfer was developed. The use of a bulky and nonredox chiral Lewis acid in the photoredox pathway successfully promoted the radical addition process and inhibited competitive reactions. Visible-light-promoted catalytic asymmetric alkylation of heteroaryl-based ketones with diverse hydrocarbons resulted in the synthesis of highly congested enantioenriched tertiary alcohols.
Review
Chemistry, Applied
Shivani Sharma, Jitender Singh, Anuj Sharma
Summary: The novel concept of radical-polar crossover (RPCO) and polar-radical crossover (PRCO) reactions has emerged in recent years as a valuable tool bridging the gap between polar and radical reactions, overcoming their limitations, and improving the green quotient of reactions. The development and transformation of this area into synthetically important reactions is summarized in this review.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Engineering, Environmental
Pengfei Gan, Yi Lu, Yunyi Li, Wen Liu, Long Chen, Meiping Tong, Jialiang Liang
Summary: An excitonic energy transfer (EET) based non-radical mechanism was proposed for the degradation of organic pharmaceuticals by g-C3N4 under visible light. The competition between single electron transfer (SET) and EET was studied, and the different mechanisms and degradation pathways were confirmed. The effect of humic acid (HA) on EET and SET was also explored, showing a distinct enhancement of EET and suppression of SET.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Food Science & Technology
Cansu Ekin Gumus, Eric Andrew Decker
Summary: Lipid oxidation is a major limitation to the shelf-life of low moisture foods and can lead to food waste. Research showed that both surface and interior lipids in crackers oxidized at similar rates, possibly due to the cracker matrix not being able to protect lipids effectively.Increasing the fat content of the crackers increased oxidation rates, possibly due to differences in the lipid structure or higher water activities in the high-fat crackers.
Article
Chemistry, Multidisciplinary
Aditya Paul, Arunava Sengupta, Somnath Yadav
Summary: This paper reports a photoresponsive electron donor-acceptor (EDA) complex, which can be detected through absorption and emission spectroscopy. Irradiation of the EDA complex with visible light triggers photoinduced single electron transfer (SET) processes that are useful for the catalyst-free, regioselective acetylation of indoles. The photocatalytic reaction with excess DAIB is also used for the synthesis of isatins. DFT and TD-DFT studies are performed to model the excited states of the EDA complex and validate the photoinduced SET mechanism.
CHEMICAL COMMUNICATIONS
(2023)
Article
Food Science & Technology
Bashar Amer, Louise Juul, Anders Hauer Moller, Hanne Sondergard Moller, Trine Kastrup Dalsgaard
Summary: Sulphite inhibited oxidative enzymes and increased the quality of protein extracted from white clover and red clover.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Louise Juul, Anders Hauer Moller, Annette Bruhn, Soren K. Jensen, Trine K. Dalsgaard
Summary: Ulvasp. is a cosmopolitan green macroalga with well-balanced amino acid composition, and extraction of protein from fresh Ulvasp. using double screw pressing with sulfite addition can lead to higher amount of native state Rubisco protein, improving protein quality.
JOURNAL OF APPLIED PHYCOLOGY
(2021)
Article
Environmental Sciences
E. D. Tsochatzis, I. E. Berggreen, J. Norgaard, G. Theodoridis, T. K. Dalsgaard
Summary: The study found that mealworms are capable of biodegrading polystyrene plastic, with varying degradation rates under different diets. Analysis of larval gut intestine tissue and frass revealed the presence of low levels of PS degradation products and other organic compounds.
Article
Chemistry, Applied
Emmanouil D. Tsochatzis, Joao Alberto Lopes, Helen Gika, Trine Kastrup Dalsgaard, Georgios Theodoridis
Summary: A simple and fast method was developed for the simultaneous determination of 75 plastic food contact materials (FCM) in liquid food simulants. The method showed adequate sensitivity, accuracy, and repeatability for most substances, and was successfully applied to the analysis of FCM multilayer items after migration testing according to current EU legislation.
Article
Chemistry, Applied
H. T. Kristensen, Q. Denon, I. Tavernier, S. B. Gregersen, M. Hammershoj, P. Van der Meeren, K. Dewettinck, T. K. Dalsgaard
Summary: This study evaluated the functional properties of WPI and PPI blends under different pH conditions and found that co-precipitation could improve the functional properties of PPI, but improvements could also be obtained by simply blending PPI and WPI.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Signe H. Nissen, Jesper M. Schmidt, Sandra Gregersen, Marianne Hammershoj, Anders H. Moller, Marianne Danielsen, Lene Stodkilde, Caroline Nebel, Trine K. Dalsgaard
Summary: Proteins extracted from alfalfa show promising functional properties for food applications, and can be enhanced through pH shift processes to improve solubility, foamability, and gelation. Addition of salt can further boost these properties, indicating the potential of alfalfa protein in food products.
FOOD HYDROCOLLOIDS
(2021)
Article
Biochemical Research Methods
Emmanouil D. Tsochatzis, Caroline Nebel, Marianne Danielsen, Ulrik K. Sundekilde, Trine Kastrup Dalsgaard
Summary: Thermal processes play a crucial role in chemical analysis and metabolomics, with optimized derivatization protocols and the use of internal standards being essential for GC metabolomics research. The speed and ramp programs of GC can impact the stability of metabolites, but this can be mitigated by the use of multiple internal standards.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Food Science & Technology
Nima Hematyar, Jan Mraz, Vlastimil Stejskal, Sabine Sampels, Zuzana Linhartova, Marketa Prokesova, Frantisek Vacha, Martin Krizek, Eva Dadakova, Hanne Sondergard Moller, Trine Kastrup Dalsgaard
Summary: The study investigated the impact of different storage conditions on the final fillet quality of Eurasian perch from different rearing systems. It was found that fillet deterioration during frozen storage was mainly caused by the formation of ice crystals followed by protein oxidation, while protein oxidation was the main concern during refrigerated storage.
Review
Agriculture, Multidisciplinary
Anders Hauer Moller, Marianne Hammershoj, Natalia Hachow Motta dos Passos, Hartono Tanambell, Lene Stodkilde, Morten Ambye-Jensen, Marianne Danielsen, Soren K. Jensen, Trine K. Dalsgaard
Summary: As the demand for protein continues to rise, exploring novel protein sources like leafy plant materials rich in enzymes such as RuBisCo is essential. Leafy crops can produce high protein yields sustainably in humid climates, and extracting protein from this green biomass for food use is the focus of green biorefinery methods.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Food Science & Technology
Hartono Tanambell, Anders Hauer Moller, Milena Corredig, Trine Kastrup Dalsgaard
Summary: This study demonstrated that addition of sodium sulfite during purification process can inhibit the effects of redox enzymes on alfalfa proteins, improving solubility and quality. However, the addition of sodium sulfite also led to reduced solubility of protein concentrate at neutral pH.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
L. Juul, M. Danielsen, C. Nebel, S. Steinhagen, A. Bruhn, S. K. Jensen, I Undeland, T. K. Dalsgaard
Summary: The study compares three protein extraction methods on Ulva fenestrata and finds that extraction at pH 8.5 yields the highest protein and best solubility. Alkaline extraction methods result in higher solubility and amino acid cross-links compared to mechanical extraction, but all methods show similar in vitro digestibility.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Chemistry, Applied
H. T. Kristensen, M. Christensen, M. S. Hansen, M. Hammershoj, T. K. Dalsgaard
Summary: The interactions between pea protein and whey protein isolates are a synergism of electrostatic interactions and disulphide bonds, with beta-lactoglobulin and legumin playing a significant role. The use of NEM and NaCl reagents significantly impacts these interactions, while SDS has no effect.
Article
Biotechnology & Applied Microbiology
L. Juul, L. Stodkilde, A. K. Ingerslev, A. Bruhn, S. K. Jensen, T. K. Dalsgaard
Summary: This study evaluates the digestibility of six different seaweed protein products and demonstrates the potential to increase seaweed nitrogen digestibility through protein extraction.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Biotechnology & Applied Microbiology
L. Juul, S. Steinhagen, A. Bruhn, S. K. Jensen, I Undeland, T. K. Dalsgaard
Summary: The study investigated three different approaches for protein extraction from Ulva fenestrata, with the combined method showing the highest protein extraction yield. By combining mechanical pressing, homogenization, and alkaline extraction, the protein extraction yield can be significantly increased.
FOOD AND BIOPRODUCTS PROCESSING
(2022)
Article
Biochemistry & Molecular Biology
Louise M. Arildsen Jakobsen, Weiwei He, Nicholas Ditzel, Marianne Danielsen, Trine K. Dalsgaard, Niklas Rye Jorgensen, Peter Bollen, Hanne C. Bertram
Summary: This study investigated the effects of whey protein complexation of vitamin D-3 supplements on bone health in rats. The results showed that complexation did not improve the bioavailability of vitamin D-3 or have any significant impact on bone strength or microstructure.
