On comparing heterogeneity across biomarkers

Multiplexed ion beam imaging of human breast tumors

(2014) Michael Angelo et al.   NATURE MEDICINE

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

(2014) Charlotte Giesen et al.   NATURE METHODS

Phylogenetic Quantification of Intra-tumour Heterogeneity

(2014) Roland F. Schwarz et al.   PLoS Computational Biology

Noise Genetics: Inferring Protein Function by Correlating Phenotype with Protein Levels and Localization in Individual Human Cells

(2014) Shlomit Farkash-Amar et al.   PLoS Genetics

A novel compound RY10-4 induces apoptosis and inhibits invasion via inhibiting STAT3 through ERK-, p38-dependent pathways in human lung adenocarcinoma A549 cells

(2013) Pingping Xue et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Multiplex Cytological Profiling Assay to Measure Diverse Cellular States

(2013) Sigrun M. Gustafsdottir et al.   PLoS One

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

(2013) X. Ni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

(2013) M. J. Gerdes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using variability in gene expression as a tool for studying gene regulation

(2013) Olivia Padovan-Merhar et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Identifying Network Motifs that Buffer Front-to-Back Signaling in Polarized Neutrophils

(2013) Yanqin Wang et al.   Cell Reports

Chapter 17: Bioimage Informatics for Systems Pharmacology

(2013) Fuhai Li et al.   PLoS Computational Biology

From Cellular Characteristics to Disease Diagnosis: Uncovering Phenotypes with Supercells

(2013) Julián Candia et al.   PLoS Computational Biology

Network Crosstalk Dynamically Changes during Neutrophil Polarization

(2012) Chin-Jen Ku et al.   CELL

Cellular Noise Regulons Underlie Fluctuations in Saccharomyces cerevisiae

(2012) Jacob Stewart-Ornstein et al.   MOLECULAR CELL

Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data

(2012) Darren R Tyson et al.   NATURE METHODS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Using Cell-to-Cell Variability--A New Era in Molecular Biology

(2012) L. Pelkmans   SCIENCE

Cellular Heterogeneity: Do Differences Make a Difference?

(2010) Steven J. Altschuler et al.   CELL

Patterns of basal signaling heterogeneity can distinguish cellular populations with different drug sensitivities

(2010) Dinesh Kumar Singh et al.   Molecular Systems Biology

Variability in gene expression underlies incomplete penetrance

(2010) Arjun Raj et al.   NATURE

Identifying single-cell molecular programs by stochastic profiling

(2010) Kevin A Janes et al.   NATURE METHODS

Heterogeneity in the physiological states and pharmacological responses of differentiating 3T3-L1 preadipocytes

(2009) Lit-Hsin Loo et al.   JOURNAL OF CELL BIOLOGY

An approach for extensibly profiling the molecular states of cellular subpopulations

(2009) Lit-Hsin Loo et al.   NATURE METHODS

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens

(2008) Zheng Yin et al.   BMC BIOINFORMATICS

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Characterizing heterogeneous cellular responses to perturbations

(2008) M. D. Slack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA