A randomized, double-blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder

Recommendations for the Primary Analysis of Continuous Endpoints in Longitudinal Clinical Trials

(2012) Craig H. Mallinckrod† et al.   DRUG INFORMATION JOURNAL

A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder

(2012) Cornelius Katona et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

A randomized clinical study of Lu AA21004 in the prevention of relapse in patients with major depressive disorder

(2012) Jean-Philippe Boulenger et al.   JOURNAL OF PSYCHOPHARMACOLOGY

A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD)

(2011) David S. Baldwin et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A double-blind, randomized, placebo-controlled, active reference study of Lu AA21004 in patients with major depressive disorder

(2011) Enric Alvarez et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Exploratory Analyses of Efficacy Data From Major Depressive Disorder Trials Submitted to the US Food and Drug Administration in Support of New Drug Applications

(2011) Ni A. Khin et al.   JOURNAL OF CLINICAL PSYCHIATRY

Discovery of 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): A Novel Multimodal Compound for the Treatment of Major Depressive Disorder

(2011) Benny Bang-Andersen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recent developments in improving signal detection and reducing placebo response in psychiatric clinical trials

(2011) Craig H. Mallinckrodt et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Why Has the Antidepressant-Placebo Difference in Antidepressant Clinical Trials Diminished over the Past Three Decades?

(2010) Arif Khan et al.   CNS Neuroscience & Therapeutics

If at First You Donʼt Succeed

(2010) K. Ryan Connolly et al.   DRUGS

Does Inclusion of a Placebo Arm Influence Response to Active Antidepressant Treatment in Randomized Controlled Trials?

(2010) Mark Sinyor et al.   JOURNAL OF CLINICAL PSYCHIATRY

Site Versus Centralized Raters in a Clinical Depression Trial

(2010) Kenneth A. Kobak et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Clinical Evidence and Potential Neurobiological Underpinnings of Unresolved Symptoms of Depression

(2009) Madhukar H. Trivedi et al.   JOURNAL OF CLINICAL PSYCHIATRY

Use of Remote Centralized Raters Via Live 2-Way Video in a Multicenter Clinical Trial for Schizophrenia

(2008) Joan Shen et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Outcomes in major depressive disorder: The evolving concept of remission and its implications for treatment

(2008) Hans-Jürgen Möller   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY