标题
NAD+metabolism: A therapeutic target for age-related metabolic disease
作者
关键词
-
出版物
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
Volume 48, Issue 4, Pages 397-408
出版商
Informa UK Limited
发表日期
2013-06-06
DOI
10.3109/10409238.2013.789479
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- Mitochondrial sirtuins and metabolic homeostasis
- (2012) Eija Pirinen et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
- (2012) Sung-Jun Park et al. CELL
- Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance
- (2012) Jun Yoshino et al. Cell Metabolism
- The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
- (2012) Carles Cantó et al. Cell Metabolism
- On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
- (2012) X. Luo et al. GENES & DEVELOPMENT
- Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) as Messengers for Calcium Mobilization
- (2012) Hon Cheung Lee JOURNAL OF BIOLOGICAL CHEMISTRY
- Exploring the therapeutic space around NAD+
- (2012) Riekelt H. Houtkooper et al. JOURNAL OF CELL BIOLOGY
- The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
- (2012) Nisha Narayan et al. NATURE
- Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
- (2012) Julie A. Mattison et al. NATURE
- Sirtuins mediate mammalian metabolic responses to nutrient availability
- (2012) Angeliki Chalkiadaki et al. Nature Reviews Endocrinology
- The many faces of insulin-like peptide signalling in the brain
- (2012) Ana M. Fernandez et al. NATURE REVIEWS NEUROSCIENCE
- Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis
- (2012) Pablo J. Fernandez-Marcos et al. Scientific Reports
- The dynamin-related protein DRP-1 and the insulin signaling pathway cooperate to modulate Caenorhabditis elegans longevity
- (2011) Christine C. Yang et al. AGING CELL
- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
- (2011) Silvie Timmers et al. Cell Metabolism
- Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice
- (2011) Jun Yoshino et al. Cell Metabolism
- PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure
- (2011) Péter Bai et al. Cell Metabolism
- PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
- (2011) Péter Bai et al. Cell Metabolism
- Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells
- (2011) Andrey Nikiforov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study
- (2011) Karen A Gelmon et al. LANCET ONCOLOGY
- Caloric restriction
- (2011) John R. Speakman et al. MOLECULAR ASPECTS OF MEDICINE
- Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase
- (2011) Wenqing Jiang et al. MOLECULAR CELL
- Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm
- (2011) Anthony K.L. Leung et al. MOLECULAR CELL
- Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
- (2011) Mohan Viswanathan et al. NATURE
- Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
- (2011) Camilla Burnett et al. NATURE
- Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
- (2011) Hyunkyung Jeong et al. NATURE MEDICINE
- Design, synthesis and biological characterization of novel inhibitors of CD38
- (2011) Min Dong et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats
- (2011) Nady Braidy et al. PLoS One
- Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling
- (2011) B. Beirowski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein 8-class secondary structure prediction using conditional neural fields
- (2011) Zhiyong Wang et al. PROTEOMICS
- Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
- (2011) J. Du et al. SCIENCE
- Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans
- (2010) Laurent Mouchiroud et al. AGING CELL
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
- RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10
- (2010) Gizem Donmez et al. CELL
- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
- (2010) Lei Zhong et al. CELL
- Metabolic Networks of Longevity
- (2010) Riekelt H. Houtkooper et al. CELL
- SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
- (2010) Tadahiro Shimazu et al. Cell Metabolism
- Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
- (2010) Carles Cantó et al. Cell Metabolism
- The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
- (2010) Riekelt H. Houtkooper et al. ENDOCRINE REVIEWS
- SIRT1 Activation by Small Molecules
- (2010) Han Dai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
- (2010) Michelle Pacholec et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolomic Analysis of Livers and Serum from High-Fat Diet Induced Obese Mice
- (2010) Hyun-Jin Kim et al. JOURNAL OF PROTEOME RESEARCH
- Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
- (2010) M William Audeh et al. LANCET
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- (2010) Matthew D. Hirschey et al. NATURE
- "Control" laboratory rodents are metabolically morbid: Why it matters
- (2010) B. Martin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
- (2010) Ruth Luthi-Carter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
- (2010) Eric Verdin et al. TRENDS IN BIOCHEMICAL SCIENCES
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
- (2010) Daniel Herranz et al. Nature Communications
- SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
- (2009) Takashi Nakagawa et al. CELL
- Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity
- (2009) Dirk Beher et al. Chemical Biology & Drug Design
- AMP-Activated Protein Kinase-Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
- (2009) J.-H. Um et al. DIABETES
- PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons
- (2009) Przemyslaw Wareski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tumours with PI3K activation are resistant to dietary restriction
- (2009) Nada Y. Kalaany et al. NATURE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
- (2009) R. J. Colman et al. SCIENCE
- Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
- (2008) Kevin J. Pearson et al. Cell Metabolism
- SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
- (2008) Alexander S. Banks et al. Cell Metabolism
- Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation
- (2008) Jérôme N. Feige et al. Cell Metabolism
- Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice
- (2008) Olesya Vakhrusheva et al. CIRCULATION RESEARCH
- Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
- (2008) Marcella Fulco et al. DEVELOPMENTAL CELL
- Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability
- (2008) Michelle M. Adams et al. EXPERIMENTAL NEUROLOGY
- Tissue-specific regulation of SIRT1 by calorie restriction
- (2008) D. Chen et al. GENES & DEVELOPMENT
- SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
- (2008) Gino Boily et al. PLoS One
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
- (2008) Jamie L. Barger et al. PLoS One
- A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
- (2008) B.-H. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sirt1 protects against high-fat diet-induced metabolic damage
- (2008) P. T. Pfluger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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