Co-localization of LTBP-2 with FGF-2 in fibrotic human keloid and hypertrophic scar

MRP1 knockdown down-regulates the deposition of collagen and leads to a reduced hypertrophic scar fibrosis

(2015) Yan Li et al.   JOURNAL OF MOLECULAR HISTOLOGY

LTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation

(2015) Clementine Menz et al.   PLoS One

Fibrosis: ultimate and proximate causes

(2014) Victor J. Thannickal et al.   JOURNAL OF CLINICAL INVESTIGATION

FGF2-induced effects on transcriptome associated with regeneration competence in adult human fibroblasts

(2013) Olga Kashpur et al.   BMC GENOMICS

The IL-6 Trans-Signaling-STAT3 Pathway Mediates ECM and Cellular Proliferation in Fibroblasts from Hypertrophic Scar

(2013) Sutapa Ray et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis

(2013) Mohamed A. Sideek et al.   MATRIX BIOLOGY

The Anti-Scar Effects of Basic Fibroblast Growth Factor on the Wound Repair In Vitro and In Vivo

(2013) Hong-Xue Shi et al.   PLoS One

LTBP2 mutations cause Weill-Marchesani and Weill-Marchesani-like syndrome and affect disruptions in the extracellular matrix

(2012) Ramona Haji-Seyed-Javadi et al.   HUMAN MUTATION

Topically Applied Flightless I Neutralizing Antibodies Improve Healing of Blistered Skin in a Murine Model of Epidermolysis Bullosa Acquisita

(2012) Zlatko Kopecki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Extracellular matrix molecules implicated in hypertrophic and keloid scarring

(2011) G.P. Sidgwick et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Therapeutic potential of fibroblast growth factor-2 for hypertrophic scars: upregulation of MMP-1 and HGF expression

(2011) Hitomi Eto et al.   LABORATORY INVESTIGATION

Genetics of keloid scarring

(2010) Barbara Shih et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome

(2010) Stephen Ho Kin Chan et al.   INTERNATIONAL JOURNAL OF CANCER

The origin of fibroblasts and mechanism of cardiac fibrosis

(2010) Guido Krenning et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LTBP-2 has multiple heparin/heparan sulfate binding sites

(2010) Mahroo K. Parsi et al.   MATRIX BIOLOGY

A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population

(2010) Mitsuko Nakashima et al.   NATURE GENETICS

Null Mutations in LTBP2 Cause Primary Congenital Glaucoma

(2009) Manir Ali et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid

(2009) Mika Ikeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of integrin-mediated TGFβ activation in the pathogenesis of pulmonary fibrosis

(2009) Amanda Goodwin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fibulins: Multiple roles in matrix structures and tissue functions

(2009) S. de Vega et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interactions between extracellular matrix and growth factors in wound healing

(2009) Gregory S. Schultz et al.   WOUND REPAIR AND REGENERATION

Comparison of the Therapeutic Effects Recombinant Human Acidic and Basic Fibroblast Growth Factors in Wound Healing in Diabetic Patients

(2008) Yi Tan et al.   JOURNAL OF HEALTH SCIENCE

IFATS Collection: Fibroblast Growth Factor-2-Induced Hepatocyte Growth Factor Secretion by Adipose-Derived Stromal Cells Inhibits Postinjury Fibrogenesis Through a c-Jun N-Terminal Kinase-Dependent Mechanism

(2008) Hirotaka Suga et al.   STEM CELLS

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY