Increased expression and dysregulated association of restriction factors and type I interferon in HIV, HCV mono- and co-infected patients

Interferon alpha (IFNα)-induced TRIM22 interrupts HCV replication by ubiquitinating NS5A

(2015) Chen Yang et al.   Cellular & Molecular Immunology

Virologic Response Following Combined Ledipasvir and Sofosbuvir Administration in Patients With HCV Genotype 1 and HIV Co-infection

(2015) Anu Osinusi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Host APOBEC3G Protein Inhibits HCV Replication through Direct Binding at NS3

(2015) Yan-Ping Zhu et al.   PLoS One

Effectiveness of HCV core antigen and RNA quantification in HCV-infected and HCV/HIV-1-coinfected patients

(2014) Lu Long et al.   BMC INFECTIOUS DISEASES

Mouse knockout models for HIV-1 restriction factors

(2014) Jan Rehwinkel   CELLULAR AND MOLECULAR LIFE SCIENCES

Investigational nucleoside and nucleotide polymerase inhibitors and their use in treating hepatitis C virus

(2014) Ivan Gentile et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Interferon-free therapies for chronic hepatitis C: toward a hepatitis C virus-free world?

(2014) Ivan Gentile et al.   Expert Review of Anti-Infective Therapy

Gene Expression Profiling To Predict and Assess the Consequences of Therapy-Induced Virus Eradication in Chronic Hepatitis C Virus Infection

(2014) J. Hou et al.   JOURNAL OF VIROLOGY

Human immunodeficiency virus type 1 Vpr increases hepatitis C virus RNA replication in cell culture

(2014) Amei Deng et al.   VIRUS RESEARCH

Higher levels of hepatitis C virus RNA found in blood donors co-infected with HIV as compared to HCV mono-infected donors

(2014) Enagnon Kazali Alidjinou et al.   Journal of Infection in Developing Countries

Emerging treatments for hepatitis C

(2013) Robert Flisiak et al.   EXPERT OPINION ON EMERGING DRUGS

Factors influencing liver fibrosis and necroinflammation in HIV/HCV coinfection and HCV monoinfection

(2013) C. Sagnelli et al.   INFECTION

Hepatitis C Virus Genotype Diversity among Intravenous Drug Users in Yunnan Province, Southwestern China

(2013) Zhihui Zhang et al.   PLoS One

Current prospects for interferon-free treatment of hepatitis C in 2012

(2012) Catherine AM Stedman   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Antiviral strategies in hepatitis C virus infection

(2012) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

Host restriction factors in retroviral infection: promises in virus-host interaction

(2012) Yong-Hui Zheng et al.   Retrovirology

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis

(2012) Angela L. Rasmussen et al.   VIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

ENCODE Tiling Array Analysis Identifies Differentially Expressed Annotated and Novel 5′ Capped RNAs in Hepatitis C Infected Liver

(2011) Milan E. Folkers et al.   PLoS One

Dysregulation of IFN System Can Lead to Poor Response to Pegylated Interferon and Ribavirin Therapy in Chronic Hepatitis C

(2011) Koji Onomoto et al.   PLoS One

An HIV-1 Resistance Polymorphism in TRIM5α Gene Among Chinese Intravenous Drug Users

(2010) Feng-Liang Liu et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Association of TRIM22 with the Type 1 Interferon Response and Viral Control during Primary HIV-1 Infection

(2010) R. Singh et al.   JOURNAL OF VIROLOGY

Massive APOBEC3 Editing of Hepatitis B Viral DNA in Cirrhosis

(2010) Jean-Pierre Vartanian et al.   PLoS Pathogens

APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load

(2009) Kavidha Reddy et al.   AIDS

Human TRIM5α Expression Levels and Reduced Susceptibility to HIV‐1 Infection

(2009) Shamman Sewram et al.   JOURNAL OF INFECTIOUS DISEASES

High Levels of Chronic Immune Activation in the T-Cell Compartments of Patients Coinfected with Hepatitis C Virus and Human Immunodeficiency Virus Type 1 and on Highly Active Antiretroviral Therapy Are Reverted by Alpha Interferon and Ribavirin Treatment

(2009) V. D. Gonzalez et al.   JOURNAL OF VIROLOGY

HIV Increases HCV Replication in a TGF-β1–Dependent Manner

(2008) Wenyu Lin et al.   GASTROENTEROLOGY

Relationship between Human Immunodeficiency Type 1 Infection and Expression of Human APOBEC3G and APOBEC3F

(2008) Nzovu K. Ulenga et al.   JOURNAL OF INFECTIOUS DISEASES

HCV Coinfection Associated with Slower Disease Progression in HIV-Infected Former Plasma Donors Naïve to ART

(2008) Xiaoyan Zhang et al.   PLoS One

The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22

(2008) Stephen D. Barr et al.   PLoS Pathogens