Pharmacological Strategies for the Management of Levodopa-Induced Dyskinesia in Patients with Parkinson’s Disease
出版年份 2014 全文链接
标题
Pharmacological Strategies for the Management of Levodopa-Induced Dyskinesia in Patients with Parkinson’s Disease
作者
关键词
Dopamine Agonist, Memantine, Amantadine, Rasagiline, Motor Fluctuation
出版物
CNS DRUGS
Volume 28, Issue 12, Pages 1155-1184
出版商
Springer Nature
发表日期
2014-10-24
DOI
10.1007/s40263-014-0205-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The acute brain response to levodopa heralds dyskinesias in Parkinson disease
- (2014) Damian M. Herz et al. ANNALS OF NEUROLOGY
- Inhibition of Adenylyl Cyclase Type 5 Prevents L-DOPA-Induced Dyskinesia in an Animal Model of Parkinson's Disease
- (2014) H.-Y. Park et al. JOURNAL OF NEUROSCIENCE
- Tozadenant (SYN115) in patients with Parkinson's disease who have motor fluctuations on levodopa: a phase 2b, double-blind, randomised trial
- (2014) Robert A Hauser et al. LANCET NEUROLOGY
- ABT-089 and ABT-894 reduce levodopa-induced dyskinesias in a monkey model of Parkinson's disease
- (2014) Danhui Zhang et al. MOVEMENT DISORDERS
- Effect of nicotine on l-dopa-induced dyskinesia in animal models of Parkinson’s disease: a systematic review and meta-analysis
- (2014) Cheng-long Xie et al. NEUROLOGICAL SCIENCES
- Presynaptic dopamine depletion predicts levodopa-induced dyskinesia in de novo Parkinson disease
- (2014) J. Y. Hong et al. NEUROLOGY
- Randomized clinical trial of topiramate for levodopa-induced dyskinesia in Parkinson's disease
- (2014) Christopher Kobylecki et al. PARKINSONISM & RELATED DISORDERS
- Functional interaction between pre-synaptic α6β2-containing nicotinic and adenosine A2Areceptors in the control of dopamine release in the rat striatum
- (2013) P Garção et al. BRITISH JOURNAL OF PHARMACOLOGY
- Nicotinic receptors regulate the dynamic range of dopamine release in vivo
- (2013) Jessica L. Koranda et al. JOURNAL OF NEUROPHYSIOLOGY
- Levodopa-induced dyskinesias in tyrosine hydroxylase deficiency
- (2013) Roser Pons et al. MOVEMENT DISORDERS
- Quantitative wearable sensors for objective assessment of Parkinson's disease
- (2013) Walter Maetzler et al. MOVEMENT DISORDERS
- Long-term safety and efficacy of preladenant in subjects with fluctuating Parkinson's disease
- (2013) Stewart A. Factor et al. MOVEMENT DISORDERS
- Randomized trial of safinamide add-on to levodopa in Parkinson's disease with motor fluctuations
- (2013) Rupam Borgohain et al. MOVEMENT DISORDERS
- Adenosine A2Areceptor antagonist istradefylline reduces daily OFF time in Parkinson's disease
- (2013) Yoshikuni Mizuno et al. MOVEMENT DISORDERS
- AFQ056 in Parkinson patients with levodopa-induced dyskinesia: 13-week, randomized, dose-finding study
- (2013) Fabrizio Stocchi et al. MOVEMENT DISORDERS
- Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson's disease
- (2013) C. Warren Olanow et al. MOVEMENT DISORDERS
- Which dyskinesia scale best detects treatment response?
- (2013) Christopher G. Goetz et al. MOVEMENT DISORDERS
- Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia
- (2013) Erwan Bezard et al. MOVEMENT DISORDERS
- Withdrawing amantadine in dyskinetic patients with Parkinson disease: The AMANDYSK trial
- (2013) F. Ory-Magne et al. NEUROLOGY
- Poor self-awareness of levodopa-induced dyskinesias in Parkinson's disease: Clinical features and mechanisms
- (2013) Sara Pietracupa et al. PARKINSONISM & RELATED DISORDERS
- Perampanel in Parkinson Disease Fluctuations
- (2012) Olivier Rascol et al. CLINICAL NEUROPHARMACOLOGY
- Targeting Glutamate Receptors to Tackle the Pathogenesis, Clinical Symptoms and Levodopa-Induced Dyskinesia Associated with Parkinson’s Disease
- (2012) Susan Duty CNS DRUGS
- Long-term efficacy and safety of safinamide as add-on therapy in early Parkinson's disease
- (2012) A. H. V. Schapira et al. EUROPEAN JOURNAL OF NEUROLOGY
- Summary of the recommendations of the EFNS/MDS-ES review on therapeutic management of Parkinson's disease
- (2012) J. J. Ferreira et al. EUROPEAN JOURNAL OF NEUROLOGY
- Memantine for axial signs in Parkinson's disease: a randomised, double-blind, placebo-controlled pilot study
- (2012) C. Moreau et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Randomized clinical trial of fipamezole for dyskinesia in Parkinson disease (FJORD study)
- (2012) P. A. LeWitt et al. NEUROLOGY
- Pardoprunox as adjunct therapy to levodopa in patients with Parkinson’s disease experiencing motor fluctuations: Results of a double-blind, randomized, placebo-controlled, trial
- (2012) O. Rascol et al. PARKINSONISM & RELATED DISORDERS
- Glutamate NMDA receptor dysregulation in Parkinson’s disease with dyskinesias
- (2011) Imtiaz Ahmed et al. BRAIN
- Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesia
- (2011) K. Elisabet Ohlin et al. BRAIN
- The interhemispheric connections of the striatum: Implications for Parkinson's disease and drug-induced dyskinesias
- (2011) Christopher A. Lieu et al. BRAIN RESEARCH BULLETIN
- Local modulation of striatal glutamate efflux by serotonin 1A receptor stimulation in dyskinetic, hemiparkinsonian rats
- (2011) Kristin B. Dupre et al. EXPERIMENTAL NEUROLOGY
- Changes in the mRNA Levels of α2A and α2C Adrenergic Receptors in Rat Models of Parkinson’s Disease and l-DOPA-Induced Dyskinesia
- (2011) Amal Alachkar et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Mechanisms underlying the onset and expression of levodopa-induced dyskinesia and their pharmacological manipulation
- (2011) Mahmoud M. Iravani et al. JOURNAL OF NEURAL TRANSMISSION
- Dopamine release from serotonergic nerve fibers is reduced in L-DOPA-induced dyskinesia
- (2011) Nina Nevalainen et al. JOURNAL OF NEUROCHEMISTRY
- Serotonergic modulation of receptor occupancy in rats treated with l-DOPA after unilateral 6-OHDA lesioning
- (2011) Adjmal Nahimi et al. JOURNAL OF NEUROCHEMISTRY
- Preladenant in patients with Parkinson's disease and motor fluctuations: a phase 2, double-blind, randomised trial
- (2011) Robert A Hauser et al. LANCET NEUROLOGY
- Perampanel, an AMPA antagonist, found to have no benefit in reducing “off” time in Parkinson's disease
- (2011) Andrew Lees et al. MOVEMENT DISORDERS
- Meta-analysis of the comparative efficacy and safety of adjuvant treatment to levodopa in later Parkinson's disease
- (2011) Rebecca Stowe et al. MOVEMENT DISORDERS
- A randomized, double-blind, placebo-controlled trial of levetiracetam for dyskinesia in Parkinson's disease
- (2011) Kitty K. Wong et al. MOVEMENT DISORDERS
- Pardoprunox in early Parkinson's disease: Results from 2 large, randomized double-blind trials
- (2011) Cristina Sampaio et al. MOVEMENT DISORDERS
- A randomized, double-blind, placebo-controlled trial of safinamide as add-on therapy in early Parkinson's disease patients
- (2011) Fabrizio Stocchi et al. MOVEMENT DISORDERS
- Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio
- (2011) Marios Politis et al. MOVEMENT DISORDERS
- AFQ056 treatment of levodopa-induced dyskinesias: Results of 2 randomized controlled trials
- (2011) Daniela Berg et al. MOVEMENT DISORDERS
- The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease
- (2011) Susan H. Fox et al. MOVEMENT DISORDERS
- Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GNDF in astroglia
- (2011) Bernardino Ossola et al. NEUROPHARMACOLOGY
- Contribution of pre-synaptic mechanisms to l-DOPA-induced dyskinesia
- (2011) M. Carta et al. NEUROSCIENCE
- The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in l-Dopa-treated parkinsonian monkeys
- (2011) Laurent Grégoire et al. PARKINSONISM & RELATED DISORDERS
- Istradefylline for Parkinson's disease patients experiencing motor fluctuations: Results of the KW-6002-US-018 study
- (2011) Emmanuelle Pourcher et al. PARKINSONISM & RELATED DISORDERS
- Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats
- (2011) Christopher J. Barnum et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Amantadine for Dyskinesias in Parkinson's Disease: A Randomized Controlled Trial
- (2011) Hideyuki Sawada et al. PLoS One
- Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease
- (2011) Véronique Sgambato-Faure et al. PROGRESS IN NEUROBIOLOGY
- Sustained-release Madopar HBS® compared with standard Madopar® in the long-term treatment of de novo parkinsonian patients
- (2010) E. Dupont et al. ACTA NEUROLOGICA SCANDINAVICA
- Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia
- (2010) Daniella Rylander et al. ANNALS OF NEUROLOGY
- mTORC1 signaling in Parkinson disease and L-DOPA-induced dyskinesia: A sensitized matter
- (2010) Emanuela Santini et al. CELL CYCLE
- Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats
- (2010) Yoshihiro Tani et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The partial dopamine agonist pardoprunox (SLV308) administered in combination with l-dopa improves efficacy and decreases dyskinesia in MPTP treated common marmosets
- (2010) K. Tayarani-Binazir et al. EXPERIMENTAL NEUROLOGY
- Preladenant, a selective A2A receptor antagonist, is active in primate models of movement disorders
- (2010) Robert A. Hodgson et al. EXPERIMENTAL NEUROLOGY
- Dopamine D1-histamine H3Receptor Heteromers Provide a Selective Link to MAPK Signaling in GABAergic Neurons of the Direct Striatal Pathway
- (2010) Estefanía Moreno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Levetiracetam for levodopa-induced dyskinesia in Parkinson’s disease: a randomized, double-blind, placebo-controlled trial
- (2010) Martin Wolz et al. JOURNAL OF NEURAL TRANSMISSION
- Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson’s disease
- (2010) Christopher Kobylecki et al. JOURNAL OF NEUROCHEMISTRY
- Pharmacokinetics of levodopa
- (2010) Manuela Contin et al. JOURNAL OF NEUROLOGY
- Reduction of L-DOPA-Induced Dyskinesia by the Selective Metabotropic Glutamate Receptor 5 Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease
- (2010) T. H. Johnston et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Nicotinic Receptor-Mediated Reduction in L-DOPA-Induced Dyskinesias May Occur via Desensitization
- (2010) T. Bordia et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap
- (2010) Paolo Calabresi et al. LANCET NEUROLOGY
- Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial
- (2010) Murat Emre et al. LANCET NEUROLOGY
- Double-blind study of pardoprunox, a new partial dopamine agonist, in early Parkinson's disease
- (2010) Juliana Bronzova et al. MOVEMENT DISORDERS
- Melevodopa/carbidopa effervescent formulation in the treatment of motor fluctuations in advanced Parkinson's disease
- (2010) Fabrizio Stocchi et al. MOVEMENT DISORDERS
- Long-term antidyskinetic efficacy of amantadine in Parkinson's disease
- (2010) Elisabeth Wolf et al. MOVEMENT DISORDERS
- Levetiracetam for the management of levodopa-induced dyskinesias in Parkinson's disease
- (2010) P. Stathis et al. MOVEMENT DISORDERS
- The α2 adrenergic antagonist fipamezole improves quality of levodopa action in Parkinsonian primates
- (2010) Tom H. Johnston et al. MOVEMENT DISORDERS
- Pardoprunox reverses motor deficits but induces only mild dyskinesia in MPTP-treated common marmosets
- (2010) Louisa Clare Johnston et al. MOVEMENT DISORDERS
- Onset of dyskinesia with adjunct ropinirole prolonged-release or additional levodopa in early Parkinson's disease
- (2010) Ray L. Watts et al. MOVEMENT DISORDERS
- Safety and efficacy of perampanel in advanced Parkinson's disease: A randomized, placebo-controlled study
- (2010) Karla Eggert et al. MOVEMENT DISORDERS
- Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease
- (2010) Manolo Carta et al. MOVEMENT DISORDERS
- Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia
- (2010) Bai-Yun Zeng et al. NEUROBIOLOGY OF DISEASE
- Serotonergic neurons mediate ectopic release of dopamine induced by l-DOPA in a rat model of Parkinson's disease
- (2010) Sylvia Navailles et al. NEUROBIOLOGY OF DISEASE
- Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys
- (2010) Nicolas Morin et al. NEUROPHARMACOLOGY
- Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys
- (2010) Christopher A. Lieu et al. PARKINSONISM & RELATED DISORDERS
- Distinct Changes in cAMP and Extracellular Signal-Regulated Protein Kinase Signalling in L-DOPA-Induced Dyskinesia
- (2010) Emanuela Santini et al. PLoS One
- Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
- (2010) M. Politis et al. Science Translational Medicine
- Genetic Inactivation of Dopamine D1 but Not D2 Receptors Inhibits L-DOPA–Induced Dyskinesia and Histone Activation
- (2009) Sanja Darmopil et al. BIOLOGICAL PSYCHIATRY
- Continuous Jejunal Levodopa Infusion in Patients With Advanced Parkinson Disease
- (2009) Karla Eggert et al. CLINICAL NEUROPHARMACOLOGY
- Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model
- (2009) Ana Muñoz et al. EXPERIMENTAL NEUROLOGY
- Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or l-DOPA in MPTP-treated common marmosets
- (2009) K.A. Stockwell et al. EXPERIMENTAL NEUROLOGY
- Dopamine transporter relation to levodopa-derived synaptic dopamine in a rat model of Parkinson’s: anin vivoimaging study
- (2009) Vesna Sossi et al. JOURNAL OF NEUROCHEMISTRY
- l-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson’s disease: temporal and quantitative relationship to the expression of dyskinesia
- (2009) Hanna S. Lindgren et al. JOURNAL OF NEUROCHEMISTRY
- Pharmacological Analysis Demonstrates Dramatic Alteration of D1 Dopamine Receptor Neuronal Distribution in the Rat Analog of L-DOPA-Induced Dyskinesia
- (2009) A. Berthet et al. JOURNAL OF NEUROSCIENCE
- Pharmacological Modulation of Glutamate Transmission in a Rat Model of L-DOPA-Induced Dyskinesia: Effects on Motor Behavior and Striatal Nuclear Signaling
- (2009) D. Rylander et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Prominent Role of 3/ 6 2* nAChRs in Regulating Evoked Dopamine Release in Primate Putamen: Effect of Long-Term Nicotine Treatment
- (2009) X. A. Perez et al. MOLECULAR PHARMACOLOGY
- Onset and spread of dyskinesias and motor symptoms in Parkinson's disease
- (2009) Giovanni Fabbrini et al. MOVEMENT DISORDERS
- NMDA antagonist memantine improves levodopa-induced dyskinesias and “On-off” phenomena in Parkinson's disease
- (2009) Sara Varanese et al. MOVEMENT DISORDERS
- Metabotropic glutamate receptor type 5 in levodopa-induced motor complications
- (2009) Bazoumana Ouattara et al. NEUROBIOLOGY OF AGING
- Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: Common implication of striatal neuropeptides
- (2009) Mohamed Khalil Tamim et al. NEUROPHARMACOLOGY
- Differential Involvement of D1 and D2 Dopamine Receptors in L-DOPA-Induced Angiogenic Activity in a Rat Model of Parkinson's Disease
- (2009) Hanna S Lindgren et al. NEUROPSYCHOPHARMACOLOGY
- Pros and cons of apomorphine and l-dopa continuous infusion in advanced Parkinson's disease
- (2009) Angelo Antonini et al. PARKINSONISM & RELATED DISORDERS
- Rodent models of treatment-induced motor complications in Parkinson's disease
- (2009) M. Angela Cenci et al. PARKINSONISM & RELATED DISORDERS
- Pharmacologic treatment of advanced Parkinson's disease: A meta-analysis of COMT inhibitors and MAO-B inhibitors
- (2009) Ripple Talati et al. PARKINSONISM & RELATED DISORDERS
- From the MPTP-treated primate to the treatment of motor complications in Parkinson's disease
- (2009) Peter Jenner PARKINSONISM & RELATED DISORDERS
- Adenosine, adenosine A2A antagonists, and Parkinson's disease
- (2009) P. Jenner et al. PARKINSONISM & RELATED DISORDERS
- The role of the dorsal raphe nucleus in the development, expression, and treatment of L-dopa-induced dyskinesia in hemiparkinsonian rats
- (2009) Karen L. Eskow et al. SYNAPSE
- Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate
- (2009) Monty A. Silverdale et al. SYNAPSE
- Adenosine A2Areceptor antagonist istradefylline (KW-6002) reduces “off” time in Parkinson's disease: A double-blind, randomized, multicenter clinical trial (6002-US-005)
- (2008) Peter A. LeWitt et al. ANNALS OF NEUROLOGY
- Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia
- (2008) A. Munoz et al. BRAIN
- BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease
- (2008) T Foltynie et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons
- (2008) T. S. Gertler et al. JOURNAL OF NEUROSCIENCE
- Study of istradefylline in patients with Parkinson's disease on levodopa with motor fluctuations
- (2008) Robert A. Hauser et al. MOVEMENT DISORDERS
- Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and parkinsonism
- (2008) John G. Nutt et al. MOVEMENT DISORDERS
- Pharmacokinetics and pharmacodynamics of levodopa
- (2008) John G. Nutt MOVEMENT DISORDERS
- Efficacy of long-term continuous subcutaneous apomorphine infusion in advanced Parkinson's disease with motor fluctuations: A multicenter study
- (2008) Pedro J. García Ruiz et al. MOVEMENT DISORDERS
- Placebo influences on dyskinesia in Parkinson's disease
- (2008) Christopher G. Goetz et al. MOVEMENT DISORDERS
- Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
- (2008) György Haskó et al. NATURE REVIEWS DRUG DISCOVERY
- PET demonstrates reduced dopamine transporter expression in PD with dyskinesias
- (2008) A. R. Troiano et al. NEUROLOGY
- A 12-week, placebo-controlled study (6002-US-006) of istradefylline in Parkinson disease
- (2008) M. Stacy et al. NEUROLOGY
- Role of receptor heterodimers in the development of l-dopa-induced dyskinesias in the 6-hydroxydopamine rat model of Parkinson's disease
- (2008) Chiara Fiorentini et al. PARKINSONISM & RELATED DISORDERS
- Priming for l-dopa-induced dyskinesia in Parkinson’s disease: A feature inherent to the treatment or the disease?
- (2008) Agnès Nadjar et al. PROGRESS IN NEUROBIOLOGY
- mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys
- (2007) Pershia Samadi et al. NEUROBIOLOGY OF AGING
- l-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation
- (2007) Barbara Picconi et al. NEUROBIOLOGY OF DISEASE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More