Axl-dependent signalling: a clinical update

Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)

(2011) Edward Thorp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinal Self-Antigen Induces a Predominantly Th1 Effector Response in Axl and Mertk Double-Knockout Mice

(2011) Fei Ye et al.   JOURNAL OF IMMUNOLOGY

Growth Arrest-Specific Protein 6 Receptor Antagonism Impairs Adipocyte Differentiation and Adipose Tissue Development in Mice

(2011) H. R. Lijnen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer

(2011) G Mudduluru et al.   ONCOGENE

The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy

(2010) A. K. Ghosh et al.   BLOOD

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

(2010) S. J. Holland et al.   CANCER RESEARCH

Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

(2010) Rachel MA Linger et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Gas6-Axl Pathway

(2010) Megan E. Cavet et al.   HYPERTENSION

Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood

(2010) C. EKMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Myeloid Zinc Finger 1 Induces Migration, Invasion, and In vivo Metastasis through Axl Gene Expression in Solid Cancer

(2010) G. Mudduluru et al.   MOLECULAR CANCER RESEARCH

AXL regulates mesothelioma proliferation and invasiveness

(2010) W-B Ou et al.   ONCOGENE

An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

(2010) X Ye et al.   ONCOGENE

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

(2010) K Vuoriluoto et al.   ONCOGENE

Association study between polymorphims in GAS6-TAM genes and carotid atherosclerosis

(2010) Begoña Hurtado et al.   THROMBOSIS AND HAEMOSTASIS

Pharmacological inhibition of Axl affects smooth muscle cell functions under oxidative stress

(2010) E.M. Smolock et al.   VASCULAR PHARMACOLOGY

Plasma Level of Growth Arrest–Specific 6 (GAS6) Protein and Genetic Variations in theGAS6Gene in Patients With Acute Coronary Syndrome

(2009) Lei Jiang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6

(2009) S. Loges et al.   BLOOD

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression

(2009) A. K. Ghosh et al.   BLOOD

Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL

(2009) L. Liu et al.   CANCER RESEARCH

Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl as markers of large abdominal aortic aneurysms

(2009) Carl Ekman et al.   CLINICAL BIOCHEMISTRY

Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis

(2009) Y Li et al.   ONCOGENE

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

(2009) C. Gjerdrum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gas6–Axl Receptor Signaling Is Regulated by Glucose in Vascular Smooth Muscle Cells

(2008) Megan E. Cavet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes

(2007) M. Tjwa et al.   BLOOD