Plasma Letrozole Concentrations in Postmenopausal Women With Breast Cancer Are Associated With CYP2A6 Genetic Variants, Body Mass Index, and Age

A prospective study of aromatase inhibitor-associated musculoskeletal symptoms and abnormalities on serial high-resolution wrist ultrasonography

(2010) N. Lynn Henry et al.   CANCER

Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation

(2010) E. T. Ogburn et al.   DRUG METABOLISM AND DISPOSITION

Aromatase inhibitors in women with clomiphene citrate resistance: a randomized, double-blind, placebo-controlled trial

(2010) Mohan S. Kamath et al.   FERTILITY AND STERILITY

NewCYP2A6gene deletion and conversion variants in a population of Black African descent

(2010) Jill C Mwenifumbo et al.   PHARMACOGENOMICS

Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4′-methanol-bisbenzonitrile in vitro

(2009) Seongwook Jeong et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Association of Nicotine Metabolite Ratio and CYP2A6 Genotype With Smoking Cessation Treatment in African-American Light Smokers

(2009) MK Ho et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo

(2009) Nael Al Koudsi et al.   PHARMACOGENOMICS JOURNAL

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

(2009) K. Murai et al.   XENOBIOTICA

Comprehensive In Vitro Analysis of Voriconazole Inhibition of Eight Cytochrome P450 (CYP) Enzymes: Major Effect on CYPs 2B6, 2C9, 2C19, and 3A

(2008) S. Jeong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Letrozole is Superior to Anastrozole in Suppressing Breast Cancer Tissue and Plasma Estrogen Levels

(2008) J. Geisler et al.   CLINICAL CANCER RESEARCH

CYP2A6 activity in a healthy Spanish population: effect of age, sex, smoking, and oral contraceptives

(2008) B Sinues et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent

(2008) Jill C. Mwenifumbo et al.   HUMAN MUTATION

A novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descent

(2008) Man Ki Ho et al.   Pharmacogenetics and Genomics