Sources, metabolism, and regulation of circulating sphingosine-1-phosphate

Granule-mediated release of sphingosine-1-phosphate by activated platelets

(2014) Deepa Jonnalagadda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The role of sphingosine-1-phosphate in endothelial barrier function

(2014) Brent A. Wilkerson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Higher level of plasma bioactive molecule sphingosine 1-phosphate in women is associated with estrogen

(2014) Shoudong Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD

(2014) A. O. Awojoodu et al.   BLOOD

Exercise increases sphingoid base-1-phosphate levels in human blood and skeletal muscle in a time- and intensity-dependent manner

(2014) Marcin Baranowski et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Ultramarathon Run Markedly Reduces Plasma Sphingosine-1-phosphate Concentration

(2014) Marcin Baranowski et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Fibroblast Growth Factor-based Signaling through Synthetic Heparan Sulfate Blocks Copolymers Studied Using High Cell Density Three-dimensional Cell Printing

(2014) Eric Sterner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosin 1-phosphate contributes in tumor progression

(2014) Nasser Samadi et al.   Journal of Cancer Research and Therapeutics

Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development

(2014) Yuquan Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate

(2014) Iryna Sutter et al.   JOURNAL OF LIPID RESEARCH

Modulation of sphingosine-1-phosphate and apolipoprotein M levels in the plasma, liver and kidneys in streptozotocin-induced diabetic mice

(2014) Takahiro Nojiri et al.   Journal of Diabetes Investigation

Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy

(2014) Masayuki Nagahashi et al.   Biomed Research International

Dose-dependent effect of aspirin on the level of sphingolipids in human blood

(2013) M Knapp et al.   Advances in Medical Sciences

Sphingosine-1-Phosphate: a Master Regulator of Lymphocyte Egress and Immunity

(2013) Szandor Simmons et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Liver involvement in sphingosine 1-phosphate dynamism revealed by adenoviral hepatic overexpression of apolipoprotein M

(2013) Makoto Kurano et al.   ATHEROSCLEROSIS

Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice

(2013) Abdel K. Salous et al.   JOURNAL OF LIPID RESEARCH

Phospholipid Transfer Protein Deficiency Decreases the Content of S1P in HDL via the Loss of its Transfer Capability

(2013) Yang Yu et al.   LIPIDS

Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration

(2013) Yoshikazu Ono et al.   Lipids in Health and Disease

Review: Novel insights into the regulation of vascular tone by sphingosine 1-phosphate

(2013) D. Kerage et al.   PLACENTA

Plasma Sphingosine-1-Phosphate Is Elevated in Obesity

(2013) Greg M. Kowalski et al.   PLoS One

Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D

(2013) J. Kikuta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sustained decrease in plasma sphingosine-1-phosphate concentration and its accumulation in blood cells in acute myocardial infarction

(2013) Małgorzata Knapp et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Decreased free sphingoid base concentration in the plasma of patients with chronic systolic heart failure

(2012) M Knapp et al.   Advances in Medical Sciences

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

(2012) Yugesh Kharel et al.   BIOCHEMICAL JOURNAL

Post-translational regulation of sphingosine kinases

(2012) Huasheng Chan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Accumulated Bending Energy Elicits Neutral Sphingomyelinase Activity in Human Red Blood Cells

(2012) David J. López et al.   BIOPHYSICAL JOURNAL

Sphingosine 1-Phosphate (S1P) Carrier-dependent Regulation of Endothelial Barrier

(2012) Brent A. Wilkerson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

(2012) Shigetomo Fukuhara et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function

(2012) A. Nijnik et al.   JOURNAL OF IMMUNOLOGY

Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells

(2012) Yu Hisano et al.   PLoS One

Stored platelets alter glycerophospholipid and sphingolipid species, which are differentially transferred to newly released extracellular vesicles

(2012) Annika Pienimaeki-Roemer et al.   TRANSFUSION

The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate

(2012) Alejandra Mendoza et al.   Cell Reports

Exercise increases plasma levels of sphingoid base-1 phosphates in humans

(2011) M. Baranowski et al.   Acta Physiologica

Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism

(2011) Ratna Karuna et al.   ATHEROSCLEROSIS

Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate

(2011) Yugesh Kharel et al.   BIOCHEMICAL JOURNAL

Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions

(2011) Samy Selim et al.   CLINICAL SCIENCE

Release of sphingosine-1-phosphate from human platelets is dependent on thromboxane formation

(2011) T. ULRYCH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease

(2011) Kelley M Argraves et al.   Lipids in Health and Disease

Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells

(2011) Xing Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

(2011) C. Christoffersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease

(2010) Katherine J. E. Sattler et al.   BASIC RESEARCH IN CARDIOLOGY

Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C

(2010) Hitoshi Ikeda et al.   CLINICA CHIMICA ACTA

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes

(2010) Ruijuan Xu et al.   FASEB JOURNAL

Redistribution of Sphingosine 1-Phosphate by Sphingosine Kinase 2 Contributes to Lymphopenia

(2010) S. C. Sensken et al.   JOURNAL OF IMMUNOLOGY

Blood sphingolipidomics in healthy humans: impact of sample collection methodology

(2010) Samar M. Hammad et al.   JOURNAL OF LIPID RESEARCH

Intrathecal increase of sphingosine 1-phosphate at early stage multiple sclerosis

(2010) Alina Kułakowska et al.   NEUROSCIENCE LETTERS

Altered sphingolipid metabolism in human endometrial cancer

(2010) Paweł Knapp et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Characterization of the ATP-dependent Sphingosine 1-Phosphate Transporter in Rat Erythrocytes

(2009) Naoki Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M

(2009) Madhumati Sevvana et al.   JOURNAL OF MOLECULAR BIOLOGY

Production and release of sphingosine 1-phosphate and the phosphorylated form of the immunomodulator FTY720

(2008) A KIHARA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The vascular S1P gradient—Cellular sources and biological significance

(2008) T HLA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

"Inside-Out" Signaling of Sphingosine-1-Phosphate: Therapeutic Targets

(2008) K. Takabe et al.   PHARMACOLOGICAL REVIEWS

Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: Role in development of hypercholesterolemic atherosclerosis

(2008) Dong Ju Son et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters

(2008) R. Ohkawa et al.   ANNALS OF CLINICAL BIOCHEMISTRY