Glycolysis inhibition by 2-deoxy-d-glucose reverts the metastatic phenotype in vitro and in vivo

Cancer Abolishes the Tissue Type-Specific Differences in the Phenotype of Energetic Metabolism

(2014) Paloma Acebo et al.   Translational Oncology

Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

(2011) Y. Zhao et al.   CANCER RESEARCH

Modeling human osteosarcoma in the mouse: From bedside to bench

(2010) Katherine A. Janeway et al.   BONE

Combining 2-deoxy-D-glucose with electron transport chain blockers: A double-edged sword

(2010) Jean Boutros et al.   CANCER BIOLOGY & THERAPY

Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells

(2010) Melissa A. Fath et al.   CANCER BIOLOGY & THERAPY

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

(2010) I. Ben Sahra et al.   CANCER RESEARCH

An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis

(2010) Joseph L. Sottnik et al.   CLINICAL & EXPERIMENTAL METASTASIS

TKTL1 Is Activated by Promoter Hypomethylation and Contributes to Head and Neck Squamous Cell Carcinoma Carcinogenesis through Increased Aerobic Glycolysis and HIF1  Stabilization

(2010) W. Sun et al.   CLINICAL CANCER RESEARCH

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

(2010) Mark Stein et al.   PROSTATE

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Selective inhibition of β-F1-ATPase mRNA translation in human tumours

(2009) Imke M. Willers et al.   BIOCHEMICAL JOURNAL

Clinical studies for improving radiotherapy with 2-deoxy-D-glucose: Present status and future prospects

(2009) BS Dwarakanath et al.   Journal of Cancer Research and Therapeutics

HIF-1α Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms

(2009) Alvaro Marin-Hernandez et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect

(2009) Yijun Chen et al.   PLoS One

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Chronic ingestion of 2-deoxy-d-glucose induces cardiac vacuolization and increases mortality in rats

(2009) Robin K. Minor et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Expression of Transketolase-like 1 and Activation of Akt in Grade IV Glioblastomas Compared With Grades II and III Astrocytic Gliomas

(2008) Hans-Ullrich Völker et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Systems biology approach to identification of biomarkers for metastatic progression in cancer

(2008) Andrey A Ptitsyn et al.   BMC BIOINFORMATICS

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Bone Tumors in Adolescents and Young Adults

(2008) Stefan S. Bielack et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer

(2008) Sigrun Langbein et al.   INTERNATIONAL JOURNAL OF CANCER

Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells

(2008) Xiaojun Xu et al.   INTERNATIONAL JOURNAL OF CANCER

A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling

(2008) Gopa Biswas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel targets with potential therapeutic applications in osteosarcoma

(2008) Chand Khanna   Current Oncology Reports