Therapeutic Potential of Tolerogenic Dendritic Cells in IBD: From Animal Models to Clinical Application

Human dendritic cell subsets

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Intestinal dendritic cells: Their role in intestinal inflammation, manipulation by the gut microbiota and differences between mice and men

(2013) Elizabeth R. Mann et al.   IMMUNOLOGY LETTERS

Effector and memory T cell responses to commensal bacteria

(2013) Yasmine Belkaid et al.   TRENDS IN IMMUNOLOGY

Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?

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Stable antigen-specific T-cell hyporesponsiveness induced by tolerogenic dendritic cells from multiple sclerosis patients

(2012) Dàlia Raϊch-Regué et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory Dendritic Cells Pulsed with Carbonic Anhydrase I Protect Mice from Colitis Induced by CD4+CD25- T Cells

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Aberrant plasmacytoid dendritic cell distribution and function in patients with Crohn's disease and ulcerative colitis

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IL-10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction — A comparative study of human clinical-applicable DC

(2011) Martine A. Boks et al.   CLINICAL IMMUNOLOGY

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

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Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

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Comparative study of clinical grade human tolerogenic dendritic cells

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Intestinal dendritic cells in the pathogenesis of inflammatory bowel disease

(2011) Sergio Rutella   WORLD JOURNAL OF GASTROENTEROLOGY

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis

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Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development

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Tolerogenic plasmacytoid DC

(2010) Benjamin M. Matta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction

(2010) G. Matteoli et al.   GUT

Th1/Th17 Immune Response Is Induced by Mesenteric Lymph Node Dendritic Cells in Crohn's Disease

(2009) Atsushi Sakuraba et al.   GASTROENTEROLOGY

NOD2 Ligation Subverts IFN-  Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity via B7-H1 Up-Regulation

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Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Successful granulocyte-colony stimulating factor treatment of Crohn's disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells

(2008) P. J. Mannon et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dexamethasone/1α-25-dihydroxyvitamin D3-treated dendritic cells suppress colitis in the SCID T-cell transfer model

(2008) Anders Elm Pedersen et al.   IMMUNOLOGY

Induction of human CD4+ regulatory T cells by mycophenolic acid-treated dendritic cells

(2008) Christine Lagaraine et al.   JOURNAL OF LEUKOCYTE BIOLOGY

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells

(2008) A. E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease

(2008) Husein Hadeiba et al.   NATURE IMMUNOLOGY