The Effects of TLR Activation on T-Cell Development and Differentiation

Reversible Blockade of Thymic Output: An Inherent Part of TLR Ligand-Mediated Immune Response

(2014) T. Demoulins et al.   JOURNAL OF IMMUNOLOGY

TLR Ligand-Induced Type I IFNs Affect Thymopoiesis

(2014) M.-L. Baron et al.   JOURNAL OF IMMUNOLOGY

Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4+CD25-LAP+ Regulatory T Cell and Is Associated with Down-Regulation of IL-17+CD4+ICOS+CXCR5+ Follicular Helper T Cells

(2014) H. Y. Wu et al.   JOURNAL OF IMMUNOLOGY

Thymic Emigration: When and How T Cells Leave Home

(2014) M. A. Weinreich et al.   JOURNAL OF IMMUNOLOGY

The role of STAT5 in the development, function, and transformation of B and T lymphocytes

(2011) Lynn M. Heltemes-Harris et al.   Annals of the New York Academy of Sciences

TH1, TH2, and TH17 cells instruct monocytes to differentiate into specialized dendritic cell subsets

(2011) M. N. Alonso et al.   BLOOD

Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation

(2011) Wendy WC van Maren et al.   BMC IMMUNOLOGY

Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells

(2011) S. Nierkens et al.   CANCER RESEARCH

LPS response and endotoxin tolerance in Flt-3L-induced bone marrow-derived dendritic cells

(2011) Julie Patenaude et al.   CELLULAR IMMUNOLOGY

The Role of the Intestinal Context in the Generation of Tolerance and Inflammation

(2011) Bernardo Sgarbi Reis et al.   Clinical & Developmental Immunology

Therapeutic plasticity of stem cells and allograft tolerance

(2011) Valeria Sordi et al.   CYTOTHERAPY

Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced Tregs

(2011) Daniela Hackl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Treatment with the TLR7 agonist R848 induces regulatory T-cell-mediated suppression of established asthma symptoms

(2011) Linh Pham Van et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differentiation of human thymic regulatory T cells at the double positive stage

(2011) Helena Nunes-Cabaço et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells

(2011) Hiroaki Ito et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-12 Converts Foxp3+ Regulatory T Cells to Interferon–γ-Producing Foxp3+ T Cells That Inhibit Colitis

(2011) Ting Feng et al.   GASTROENTEROLOGY

CCL17 Promotes Intestinal Inflammation in Mice and Counteracts Regulatory T Cell–Mediated Protection From Colitis

(2011) Alexander F. Heiseke et al.   GASTROENTEROLOGY

The Transcription Factor STAT3 Is Required for T Helper 2 Cell Development

(2011) Gretta L. Stritesky et al.   IMMUNITY

Asymmetric Proteasome Segregation as a Mechanism for Unequal Partitioning of the Transcription Factor T-bet during T Lymphocyte Division

(2011) John T. Chang et al.   IMMUNITY

Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense

(2011) Fabiola Osorio et al.   IMMUNITY

CD8+ T Cells: Foot Soldiers of the Immune System

(2011) Nu Zhang et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Control of central and peripheral tolerance by Aire

(2011) Todd C. Metzger et al.   IMMUNOLOGICAL REVIEWS

Mechanisms of tolerance

(2011) Jeffrey A. Bluestone   IMMUNOLOGICAL REVIEWS

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

(2011) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

Triggering of toll-like receptor signaling pathways in T cells contributes to the anti-tumor efficacy of T cell responses

(2011) Mohamed Labib Salem   IMMUNOLOGY LETTERS

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Polymeric Structure and Host Toll-like Receptor 4 Dictate Immunogenicity of NY-ESO-1 Antigenin Vivo

(2011) Yanan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dichotomous Effects of IFN-  on Dendritic Cell Function Determine the Extent of IL-12-Driven Antitumor T Cell Immunity

(2011) J. L. Harden et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge:  -Catenin Is Dispensable for T Cell Effector Differentiation, Memory Formation, and Recall Responses

(2011) M. Prlic et al.   JOURNAL OF IMMUNOLOGY

Wnt5a Skews Dendritic Cell Differentiation to an Unconventional Phenotype with Tolerogenic Features

(2011) Jaris Valencia et al.   JOURNAL OF IMMUNOLOGY

Inhibition of Autoimmune Diabetes by TLR2 Tolerance

(2011) Do-Hoon Kim et al.   JOURNAL OF IMMUNOLOGY

Physiologic Control of the Functional Status of Foxp3+ Regulatory T Cells

(2011) A. L. Mellor et al.   JOURNAL OF IMMUNOLOGY

Stat6 and c-Jun Mediate Th2 Cell-Specific IL-24 Gene Expression

(2011) Anupama Sahoo et al.   JOURNAL OF IMMUNOLOGY

TLR2 Signaling and Th2 Responses Drive Tannerella forsythia-Induced Periodontal Bone Loss

(2011) S. R. Myneni et al.   JOURNAL OF IMMUNOLOGY

A New Subset of CD103+CD8 + Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity

(2011) K. Fujimoto et al.   JOURNAL OF IMMUNOLOGY

TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function

(2011) M. H. Nyirenda et al.   JOURNAL OF IMMUNOLOGY

TLR4 Signaling via MyD88 and TRIF Differentially Shape the CD4+ T Cell Response to Porphyromonas gingivalis Hemagglutinin B

(2011) D. E. Gaddis et al.   JOURNAL OF IMMUNOLOGY

Genome-Wide Analysis Reveals Unique Regulation of Transcription of Th2-Specific Genes by GATA3

(2011) S. Horiuchi et al.   JOURNAL OF IMMUNOLOGY

TLR1/TLR2 Agonist Induces Tumor Regression by Reciprocal Modulation of Effector and Regulatory T Cells

(2011) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Virus Selectively Primes Human Langerhans Cells for CD70 Expression Promoting CD8+ T Cell Responses

(2011) A. M. G. van der Aar et al.   JOURNAL OF IMMUNOLOGY

CD8+ T Cell Immunodominance in Lymphocytic Choriomeningitis Virus Infection Is Modified in the Presence of Toll-Like Receptor Agonists

(2011) S. Siddiqui et al.   JOURNAL OF VIROLOGY

Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

(2011) H Nakano et al.   Mucosal Immunology

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

(2011) Laura A. Solt et al.   NATURE

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses

(2011) Matthew J. Billard et al.   PLoS One

Different Toll-Like Receptor Stimuli Have a Profound Impact on Cytokines Required to Break Tolerance and Induce Autoimmunity

(2011) Albert C. C. Lin et al.   PLoS One

Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells

(2011) S. Chiesa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T cells inhibit acute IFN-  synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10

(2011) D. K. Sojka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Langerhans cells are precommitted to immune tolerance induction

(2011) E. Shklovskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatocyte entry leads to degradation of autoreactive CD8 T cells

(2011) V. Benseler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions

(2011) C. Taflin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Sos1 deletion reveals its critical role in early T-cell development

(2011) R. L. Kortum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Innate Immune Sensing of DNA

(2011) Shruti Sharma et al.   PLoS Pathogens

Clinical Operational Tolerance After Renal Transplantation

(2010) Giuseppe Orlando et al.   ANNALS OF SURGERY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Toll-like Receptors in Regulatory T Cells of Patients With Head and Neck CancerTLRs in T-reg Cells of HNSCC Patients

(2010) Clarissa Anni Wild   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Toll-like receptors and their adapter molecules

(2010) A. I. Tukhvatulin et al.   BIOCHEMISTRY-MOSCOW

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

Insights into the role of Toll-like receptors in modulation of T cell responses

(2010) Raveendra Kulkarni et al.   CELL AND TISSUE RESEARCH

miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine

(2010) Cécilia Chassin et al.   Cell Host & Microbe

Modulation of immune responses through direct activation of Toll-like receptors to T cells

(2010) G. Liu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Localisation and trafficking of Toll-like receptors: an important mode of regulation

(2010) Anne F McGettrick et al.   CURRENT OPINION IN IMMUNOLOGY

Effector and memory CD8+ T cell differentiation: toward a molecular understanding of fate determination

(2010) Gabrielle T Belz et al.   CURRENT OPINION IN IMMUNOLOGY

Becoming self-aware: the thymic education of regulatory T cells

(2010) Chan-Wang J Lio et al.   CURRENT OPINION IN IMMUNOLOGY

T-bet-mediated differentiation of the activated CD8+ T cell

(2010) Crystal J. J. Yeo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tolerogenic plasmacytoid DC

(2010) Benjamin M. Matta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunologic Basis of Graft Rejection and Tolerance Following Transplantation of Liver or Other Solid Organs

(2010) Alberto Sánchez–Fueyo et al.   GASTROENTEROLOGY

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction

(2010) G. Matteoli et al.   GUT

Identification of FABP7 in fibroblastic reticular cells of mouse lymph nodes

(2010) Nobuko Tokuda et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease

(2010) Joseph M. Reynolds et al.   IMMUNITY

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

(2010) Madhav D. Sharma et al.   IMMUNITY

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Modular Utilization of Distal cis-Regulatory Elements Controls Ifng Gene Expression in T Cells Activated by Distinct Stimuli

(2010) Anand Balasubramani et al.   IMMUNITY

Differential expression of toll-like receptor signaling cascades in LPS-tolerant human peripheral blood mononuclear cells☆

(2010) Marialice Erdelyi Mendes et al.   IMMUNOBIOLOGY

Subsets of migrating intestinal dendritic cells

(2010) Simon Milling et al.   IMMUNOLOGICAL REVIEWS

Polyclonal Treg cells enhance the activity of a mucosal adjuvant

(2010) Silvia Vendetti et al.   IMMUNOLOGY AND CELL BIOLOGY

Important aspects of Toll-like receptors, ligands and their signaling pathways

(2010) Z. L. Chang   INFLAMMATION RESEARCH

Analysis of a TIR-less Splice Variant of TRIF Reveals an Unexpected Mechanism of TLR3-mediated Signaling

(2010) Ke-Jun Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Suppressive T Cell Factor 1 (TCF-1) Isoforms in Naive CD4+T Cells Is Mediated by IL-4/STAT6 Signaling

(2010) Elisabeth Maier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunomodulatory Effects of dsRNA and Its Potential as Vaccine Adjuvant

(2010) Bo Jin et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination

(2010) Bram Slütter et al.   JOURNAL OF CONTROLLED RELEASE

One naive T cell, multiple fates in CD8+T cell differentiation

(2010) Carmen Gerlach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

(2010) Jarish N. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

(2010) Anne L. Fletcher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential but Direct Abolishment of Human Regulatory T Cell Suppressive Capacity by Various TLR2 Ligands

(2010) H. H. Oberg et al.   JOURNAL OF IMMUNOLOGY

CD30 Discriminates Heat Shock Protein 60-Induced FOXP3+CD4+ T Cells with a Regulatory Phenotype

(2010) I. de Kleer et al.   JOURNAL OF IMMUNOLOGY

An Intrinsic Mechanism Predisposes Foxp3-Expressing Regulatory T Cells to Th2 Conversion In Vivo

(2010) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

T and B Cells Are Not Required for Clearing Staphylococcus aureus in Systemic Infection Despite a Strong TLR2-MyD88-Dependent T Cell Activation

(2010) M. Schmaler et al.   JOURNAL OF IMMUNOLOGY

Signaling Pathways in T Follicular Helper Cells

(2010) J. Rolf et al.   JOURNAL OF IMMUNOLOGY

IL-1 -Mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-Producing Cells

(2010) L. Li et al.   JOURNAL OF IMMUNOLOGY

STAT5 Is Critical To Maintain Effector CD8+ T Cell Responses

(2010) P. Tripathi et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Hematopoietic-Derived APCs Select Regulatory T Cells in Thymus

(2010) E. Roman et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche

(2010) A. Banerjee et al.   JOURNAL OF IMMUNOLOGY

TLR2 Agonists Enhance CD8+Foxp3+ Regulatory T Cells and Suppress Th2 Immune Responses during Allergen Immunotherapy

(2010) Y.-G. Tsai et al.   JOURNAL OF IMMUNOLOGY

Enhanced Tumor Eradication by Combining CTLA-4 or PD-1 Blockade With CpG Therapy

(2010) Sara M. Mangsbo et al.   JOURNAL OF IMMUNOTHERAPY

Regulation of antigen uptake, migration, and lifespan of dendritic cell by Toll-like receptors

(2010) Ivan Zanoni et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NF-κB-mediated expression of MAPK phosphatase-1 is an early step in desensitization to TLR ligands in enterocytes

(2010) J Wang et al.   Mucosal Immunology

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

(2010) Shane Crotty et al.   NATURE IMMUNOLOGY

Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance

(2010) Maria Hinterberger et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Epithelial crosstalk at the microbiota-mucosal interface

(2010) J. M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival

(2010) T. W. Hand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Toll-like receptors in the development of immunotolerance mediated by probiotics

(2010) Carolina Gómez-Llorente et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Signals that influence T follicular helper cell differentiation and function

(2010) Michelle A. Linterman et al.   Seminars in Immunopathology

Educating CD4 T cells with vaccine adjuvants: lessons from lipopolysaccharide

(2010) Jeremy P. McAleer et al.   TRENDS IN IMMUNOLOGY

The elusive identity of T follicular helper cells

(2010) Di Yu et al.   TRENDS IN IMMUNOLOGY

The lymph as a pool of self-antigens

(2010) Cristina C. Clement et al.   TRENDS IN IMMUNOLOGY

Lymph node stroma broaden the peripheral tolerance paradigm

(2010) Anne L. Fletcher et al.   TRENDS IN IMMUNOLOGY

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

(2009) Susan Carpenter et al.   BIOCHEMICAL JOURNAL

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes

(2009) M. D. Sharma et al.   BLOOD

Pattern recognition receptors of innate immunity and their application to tumor immunotherapy

(2009) Tsukasa Seya et al.   CANCER SCIENCE

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

(2009) Simin Rahighi et al.   CELL

The Current STATus of lymphocyte signaling: new roles for old players

(2009) Adewole S Adamson et al.   CURRENT OPINION IN IMMUNOLOGY

Regulation of the cytosolic DNA-sensing system in innate immunity: a current view

(2009) Hideyuki Yanai et al.   CURRENT OPINION IN IMMUNOLOGY

TLR2 engagement on memory CD8+T cells improves their cytokine-mediated proliferation and IFN-γ secretion in the absence of Ag

(2009) Anne Cottalorda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Dendritic Cells Induce the Differentiation of Interleukin-21-Producing T Follicular Helper-like Cells through Interleukin-12

(2009) Nathalie Schmitt et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Control of Regulatory T Cell Lineage Commitment and Maintenance

(2009) Steven Z. Josefowicz et al.   IMMUNITY

Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

(2009) Axel Kallies et al.   IMMUNITY

A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection

(2009) Haina Shin et al.   IMMUNITY

Regulating functional cell fates in CD8 T cells

(2009) Protul A. Shrikant et al.   IMMUNOLOGIC RESEARCH

The contribution of direct TLR signaling to T cell responses

(2009) Adeeb H. Rahman et al.   IMMUNOLOGIC RESEARCH

Antigenic dietary protein guides maturation of the host immune system promoting resistance toLeishmania majorinfection in C57BL/6 mice

(2009) Joana F. Amaral et al.   IMMUNOLOGY

The role of innate signaling in the homeostasis of tolerance and immunity in the intestine

(2009) Jerry M. Wells et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling

(2009) Stefanie Eyerich et al.   JOURNAL OF CLINICAL INVESTIGATION

Nine lives: plasticity among T helper cell subsets: Figure 1.

(2009) Richard M. Locksley   JOURNAL OF EXPERIMENTAL MEDICINE

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells

(2009) Oliver Dienz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

(2009) Ryutaro Fukui et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation requirements and responses to TLR ligands in human CD4+ T cells: Comparison of two T cell isolation techniques

(2009) Christina L. Lancioni et al.   JOURNAL OF IMMUNOLOGICAL METHODS

TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells

(2009) C. K. Holm et al.   JOURNAL OF IMMUNOLOGY

Hyporesponsiveness of Intestinal Dendritic Cells to TLR Stimulation Is Limited to TLR4

(2009) V. Cerovic et al.   JOURNAL OF IMMUNOLOGY

TLR2 Promotes Th2/Th17 Responses via TLR4 and TLR7/8 by Abrogating the Type I IFN Amplification Loop

(2009) M. H. Wenink et al.   JOURNAL OF IMMUNOLOGY

The Original Intrathymic Progenitor from Which T Cells Originate

(2009) J. C. Zuniga-Pflucker   JOURNAL OF IMMUNOLOGY

Activation of Melanoma Differentiation-Associated Gene 5 Causes Rapid Involution of the Thymus

(2009) David Anz et al.   JOURNAL OF IMMUNOLOGY

TLR2 Engagement on CD8 T Cells Enables Generation of Functional Memory Cells in Response to a Suboptimal TCR Signal

(2009) B. C. Mercier et al.   JOURNAL OF IMMUNOLOGY

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

(2009) B. Baban et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

(2009) Fuminori Tokunaga et al.   NATURE CELL BIOLOGY

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

(2009) Ping-Hui Tseng et al.   NATURE IMMUNOLOGY

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Mechanisms maintaining peripheral tolerance

(2009) Daniel L Mueller   NATURE IMMUNOLOGY

T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-γ

(2009) Qing Yu et al.   NATURE IMMUNOLOGY

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

(2009) Linda Yip et al.   NATURE IMMUNOLOGY

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

(2009) Markus Feuerer et al.   NATURE IMMUNOLOGY

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

(2009) Luca Gattinoni et al.   NATURE MEDICINE

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Different T Cell Receptor Signals Determine CD8+ Memory Versus Effector Development

(2009) E. Teixeiro et al.   SCIENCE

Cytoplasmic nucleic acid sensors in antiviral immunity

(2009) Priya Ranjan et al.   TRENDS IN MOLECULAR MEDICINE

T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses

(2008) Cecile King et al.   Annual Review of Immunology

Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

(2008) F. Eddahri et al.   BLOOD

A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

(2008) M. Quigley et al.   BLOOD

Sensing of Viral Infection and Activation of Innate Immunity by Toll-Like Receptor 3

(2008) E. Vercammen et al.   CLINICAL MICROBIOLOGY REVIEWS

STAT4: Genetics, mechanisms, and implications for autoimmunity

(2008) Benjamin D. Korman et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Thymoproteasome: probable role in generating positively selecting peptides

(2008) Shigeo Murata et al.   CURRENT OPINION IN IMMUNOLOGY

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation

(2008) Maria A. Curotto de Lafaille et al.   IMMUNITY

Plasmacytoid Dendritic Cells Mediate Oral Tolerance

(2008) Anne Goubier et al.   IMMUNITY

A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells

(2008) Alexis Vogelzang et al.   IMMUNITY

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Pattern recognition receptors and control of adaptive immunity

(2008) Noah W. Palm et al.   IMMUNOLOGICAL REVIEWS

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

DAP10- and DAP12-associated receptors in innate immunity

(2008) Lewis L. Lanier   IMMUNOLOGICAL REVIEWS

TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA

(2008) Annapoorani Chockalingam et al.   IMMUNOLOGY AND CELL BIOLOGY

TAB4 Stimulates TAK1-TAB1 Phosphorylation and Binds Polyubiquitin to Direct Signaling to NF-κB

(2008) Todd D. Prickett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

(2008) Cristiana Guiducci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dissecting T cell lineage relationships by cellular barcoding

(2008) Koen Schepers et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll-like receptor (TLR) gene expression in human primary macrophages

(2008) Minja Miettinen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

(2008) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

(2008) N. van Panhuys et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells in the thymus contribute to T-regulatory cell induction

(2008) A. I. Proietto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE

Functional differences between M cells and enterocytes in sampling luminal antigens

(2008) Jennelle M. Kyd et al.   VACCINE

Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRγ

(2007) Ching-Liang Chu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY