Epigenetic Genome Mining of an Endophytic Fungus Leads to the Pleiotropic Biosynthesis of Natural Products

Identification of a gene cluster responsible for the biosynthesis of cyclic lipopeptide verlamelin

(2014) Kei-ichi Ishidoh et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Discovering the secondary metabolite potential encoded within entomopathogenic fungi

(2014) Donna M. Gibson et al.   NATURAL PRODUCT REPORTS

Aflatoxin and deconstruction of type I, iterative polyketide synthase function

(2014) Craig A. Townsend   NATURAL PRODUCT REPORTS

Fungal natural products in research and development

(2014) Anja Schueffler et al.   NATURAL PRODUCT REPORTS

Calcaripeptides A–C, Cyclodepsipeptides from a Calcarisporium Strain

(2013) Johanna Silber et al.   JOURNAL OF NATURAL PRODUCTS

Coupled Methyl Group Epimerization and Reduction by Polyketide Synthase Ketoreductase Domains. Ketoreductase-Catalyzed Equilibrium Isotope Exchange

(2013) Ashish Garg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereochemistry of Reductions Catalyzed by Methyl-Epimerizing Ketoreductase Domains of Polyketide Synthases

(2013) Young-Ok You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Calcarides A–E, Antibacterial Macrocyclic and Linear Polyesters from a Calcarisporium Strain

(2013) Johanna Silber et al.   Marine Drugs

The chromatin code of fungal secondary metabolite gene clusters

(2012) Agnieszka Gacek et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Endophytic fungi: novel sources of anticancer lead molecules

(2012) Sheela Chandra   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation

(2012) Gulay Ozcengiz et al.   BIOTECHNOLOGY ADVANCES

Chemical Ecology of Endophytic Fungi: Origins of Secondary Metabolites

(2012) Souvik Kusari et al.   CHEMISTRY & BIOLOGY

Characterization of a Silent Azaphilone Gene Cluster from Aspergillus niger ATCC 1015 Reveals a Hydroxylation-Mediated Pyran-Ring Formation

(2012) Angelica O. Zabala et al.   CHEMISTRY & BIOLOGY

Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain

(2012) Xue Gao et al.   Nature Chemical Biology

Identification and Characterization of a Novel Diterpene Gene Cluster in Aspergillus nidulans

(2012) Kirsi Bromann et al.   PLoS One

Isolation and characterization of the citrinin biosynthetic gene cluster from Monascus aurantiacus

(2011) Yan-Ping Li et al.   BIOTECHNOLOGY LETTERS

Nongenetic Reprogramming of a Fungal Highly Reducing Polyketide Synthase

(2011) Ahmed A. Yakasai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase

(2011) Mustafa Köksal et al.   Nature Chemical Biology

Secondary metabolism in fungi: does chromosomal location matter?

(2010) Jonathan M Palmer et al.   CURRENT OPINION IN MICROBIOLOGY

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

Two rings in them all: The labdane-related diterpenoids

(2010) Reuben J. Peters   NATURAL PRODUCT REPORTS

Fungal cyclooligomerdepsipeptides: From classical biochemistry to combinatorial biosynthesis

(2010) Roderich Süssmuth et al.   NATURAL PRODUCT REPORTS

Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

(2010) Mustafa Köksal et al.   NATURE

HdaA, a class 2 histone deacetylase of Aspergillus fumigatus, affects germination and secondary metabolite production

(2009) Inhyung Lee et al.   FUNGAL GENETICS AND BIOLOGY

The Biochemical Basis for Stereochemical Control in Polyketide Biosynthesis

(2009) Chiara R. Valenzano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster

(2009) J.W. Cary et al.   MYCOLOGIA

Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

(2009) Robert H. Cichewicz   NATURAL PRODUCT REPORTS