Cardiac-Specific Inducible and Conditional Gene Targeting in Mice

Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: An in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects

(2012) Alejandro Lencinas et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

(2012) Mohamad Azhar et al.   International Journal of Biological Sciences

Heart Valve Structure and Function in Development and Disease

(2011) Robert B. Hinton et al.   Annual Review of Physiology

The emerging genetic landscape underlying cardiac conduction system function

(2011) David E. Arnolds et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Genetic Analysis in Cardiovascular Disease

(2011) Edwin Ho et al.   Cardiology in Review

Transforming growth factor beta signaling in adult cardiovascular diseases and repair

(2011) Thomas Doetschman et al.   CELL AND TISSUE RESEARCH

Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation

(2011) Bingruo Wu et al.   CIRCULATION RESEARCH

Twenty Years of Gene Targeting

(2011) Jeffrey Robbins   CIRCULATION RESEARCH

Efficient inducible Cre-mediated recombination in Tcf21cell lineages in the heart and kidney

(2011) Asha Acharya et al.   GENESIS

Inducible recombination in the cardiac conduction system of minK: CreERT2 BAC transgenic mice

(2011) David E. Arnolds et al.   GENESIS

Genome Engineering With Zinc-Finger Nucleases

(2011) Dana Carroll   GENETICS

Epicardial epithelial-to-mesenchymal transition in injured heart

(2011) Bin Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Sequence-based characterization of structural variation in the mouse genome

(2011) Binnaz Yalcin et al.   NATURE

Lessons on the pathogenesis of aneurysm from heritable conditions

(2011) Mark E. Lindsay et al.   NATURE

De novo cardiomyocytes from within the activated adult heart after injury

(2011) Nicola Smart et al.   NATURE

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Heritable gene targeting in zebrafish using customized TALENs

(2011) Peng Huang et al.   NATURE BIOTECHNOLOGY

A resource of vectors and ES cells for targeted deletion of microRNAs in mice

(2011) Haydn M Prosser et al.   NATURE BIOTECHNOLOGY

Knockout rats generated by embryo microinjection of TALENs

(2011) Laurent Tesson et al.   NATURE BIOTECHNOLOGY

A Non-Specific Effect Associated with Conditional Transgene Expression Based on Cre-loxP Strategy in Mice

(2011) Linghua Qiu et al.   PLoS One

Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo

(2011) J. H. van Berlo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enfermedad cardiovascular en el anciano

(2011) Charles F. Jackson et al.   REVISTA ESPANOLA DE CARDIOLOGIA

TAL Effectors: Customizable Proteins for DNA Targeting

(2011) A. J. Bogdanove et al.   SCIENCE

The Inter-Relationship of Periostin, TGFβ, and BMP in Heart Valve Development and Valvular Heart Diseases

(2011) Simon J. Conway et al.   TheScientificWorldJOURNAL

MicroRNAs in cardiac disease

(2011) Gerald W. Dorn   Translational Research

Developmental basis of adult cardiovascular diseases

(2010) Roger R. Markwald et al.   Annals of the New York Academy of Sciences

MicroRNAs Add a New Dimension to Cardiovascular Disease

(2010) Eric M. Small et al.   CIRCULATION

Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects

(2010) Sunyong Tang et al.   DEVELOPMENTAL BIOLOGY

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Inducible Cx40-Cre expression in the cardiac conduction system and arterial endothelial cells

(2010) Sabrina Beyer et al.   GENESIS

Targeted Genome Modification in Mice Using Zinc-Finger Nucleases

(2010) I. D. Carbery et al.   GENETICS

Epicardium-derived cells: a new source of regenerative capacity

(2010) J. M. Vieira et al.   HEART

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

A TALE nuclease architecture for efficient genome editing

(2010) Jeffrey C Miller et al.   NATURE BIOTECHNOLOGY

The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium

(2010) M. Ringwald et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

MicroRNA Regulation of Cardiovascular Development

(2009) Kimberly R. Cordes et al.   CIRCULATION RESEARCH

Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart

(2009) Bin Zhou et al.   DEVELOPMENTAL BIOLOGY

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

(2009) K. Anastassiadis et al.   Disease Models & Mechanisms

Generation of mice with a conditional allele for transforming growth factor beta 1 gene

(2009) Mohamad Azhar et al.   GENESIS

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

(2009) Norifumi Takeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue–Tissue Interactions During Morphogenesis of the Outflow Tract

(2009) Stacey Rentschler et al.   PEDIATRIC CARDIOLOGY

New Mouse Lines for the Analysis of Neuronal Morphology Using CreER(T)/loxP-Directed Sparse Labeling

(2009) Tudor C. Badea et al.   PLoS One

Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

(2009) Aron M. Geurts et al.   SCIENCE

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis

(2009) Stefan Glaser et al.   Epigenetics & Chromatin

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects

(2008) Ying Zhang et al.   DEVELOPMENTAL BIOLOGY

Gene targeted ablation of high molecular weight fibroblast growth factor-2

(2008) Mohamad Azhar et al.   DEVELOPMENTAL DYNAMICS

Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse

(2008) Olivia Wendling et al.   GENESIS

Multicenter research in adult congenital heart disease

(2008) Paul Khairy et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Tamoxifen-inducible gene deletion in the cardiac conduction system

(2008) Evelyn Hoesl et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Genetic approaches for changing the heart and dissecting complex syndromes

(2008) Michael-Alice Moga et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

With great power comes great responsibility: Using mouse genetics to study cardiac hypertrophy and failure

(2008) Jeffery D. Molkentin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles

(2008) Willem J. de Lange et al.   PHYSIOLOGICAL GENOMICS

Suitability of tamoxifen-induced mutagenesis for behavioral phenotyping

(2007) M.A. Vogt et al.   EXPERIMENTAL NEUROLOGY