Editorial Material
Optics
Andreas Aigner, Judith M. Dawes, Stefan A. Maier, Haoran Ren
Summary: Researchers provide a comprehensive review of hyperbolic metamaterials, explaining key nanophotonic concepts and describing a range of applications for these versatile materials.
LIGHT-SCIENCE & APPLICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Liisa Holm, Aleksi Laiho, Petri Toronen, Marco Salgado
Summary: Structural comparison can detect remote homology missed by sequence comparison. The DALI web server offers structural analysis tools such as database searches, interactive visualization, and 3D structure alignment. In this study, we used DALI to mine the AlphaFold Database and discovered 100 previously unreported remote homologous relationships. The findings provided insights into protein families and allowed for the generation of functional hypotheses for further exploration in structural biology studies.
Article
Psychology, Multidisciplinary
Emilio Moyano-Diaz, Rodolfo Mendoza-Llanos
Summary: The research findings indicate that among Chilean participants, decision-making style remains consistent across different domains, with health being the most emphasized one, where individuals tend to maximize their decisions.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Astronomy & Astrophysics
Jason T. Hinkle, Christopher S. Kochanek, Benjamin J. Shappee, Patrick J. Vallely, Katie Auchettl, Michael Fausnaugh, Thomas W-S Holoien, Helena P. Treiber, Anna Payne, B. Scott Gaudi, Keivan G. Stassun, Todd A. Thompson, J. L. Tonry, Steven Villanueva Jr
Summary: We analyzed data from TESS on the ambiguous nuclear transient ASASSN-18el and found that the optical changing-look phenomenon is likely due to extreme AGN activity rather than a TDE. The short-time-scale stochastic variability observed is consistent with an AGN, and fitting the TESS light curve with a DRW model provides a rest-frame variability amplitude and time-scale. The estimated tDRW for ASASSN-18el is broadly consistent with a relationship between DRW time-scale and central supermassive black hole mass.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2023)
Article
Ecology
Kevin Felix Arno Darras, Ellena Yusti, Joe Chun-Chia Huang, Delphine-Clara Zemp, Agus Priyono Kartono, Thomas Cherico Wanger
Summary: The study demonstrates the potential of emerging technologies in biodiversity sampling, particularly in bat point counts, to improve sampling efficiency and accuracy. Bat point counts proved to be similarly effective but more time-efficient than traditional methods in sampling bat species in oil palm plantations.
ECOLOGY AND EVOLUTION
(2021)
Article
Biochemistry & Molecular Biology
Stefan Schulze, Friedhelm Pfeiffer, Benjamin A. Garcia, Mechthild Pohlschroder
Summary: This study extended the phenotypic characterization of N-glycosylation pathway mutants in Haloferax volcanii and provided a detailed glycoproteome for this model archaeon. Through in-depth glycoproteomic analyses, the largest archaeal glycoproteome described so far was identified, revealing the complexity of N-glycosylation pathways in archaeal cell biology.
Article
Oncology
Wenqing Qi, Wojciech Rosikiewicz, Zhaohong Yin, Beisi Xu, Huihong Jiang, Shibiao Wan, Yiping Fan, Gang Wu, Lu Wang
Summary: Mesenchymal chondrosarcoma is a rare and aggressive primitive mesenchymal tumor that mainly affects adolescents and young adults. Researchers have identified the fusion protein HEY1-NCOA2, which promotes cell proliferation and upregulates the expression of PDGFB and PDGFRA, providing a potential target for treating mesenchymal chondrosarcoma.
JOURNAL OF PATHOLOGY
(2022)
Article
Chemistry, Physical
Yechen Wang, Yaru Wang, Jianjun Zhao, Yiming Xu
Summary: The study examined the effects of different cations and anions on the production of H2O2 under semiconductor photocatalysis conditions. The results showed that specific ions can greatly promote or inhibit the production of H2O2, and there may also be interactions between certain ions.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2021)
Article
Political Science
Andrew M. Guess
Summary: Most people have moderate online media diets, with a small group leaning towards ideologically slanted websites. There is a significant overlap in media diets between Democrats and Republicans, but some individuals still drive a disproportionate amount of traffic to specific biased websites.
AMERICAN JOURNAL OF POLITICAL SCIENCE
(2021)
Article
Computer Science, Information Systems
Helin Li, Hui Zhu, Xiaodong Lin, Rongxing Lu, Zhipeng Yu, Wei Lan
Summary: With the application of artificial intelligence in online social networks, the user experience has been improved, but the risk of data misuse has also increased. In order to address the issue of users' reluctance to share their true intentions due to privacy concerns, this paper proposes an effective intention-concealing visitation framework named Aviv.
COMPUTERS & SECURITY
(2022)
Article
Automation & Control Systems
Chris Mingard, Guillermo Valle-Perez, Joar Skalse, Ard A. Louis
Summary: The study found that deep neural networks exhibit strong inductive bias in the overparameterised regime, primarily due to the characteristics of the parameter-function map. The Bayesian posterior probability is a key factor influencing DNN's generalisation ability, closely related to the performance of stochastic gradient descent.
JOURNAL OF MACHINE LEARNING RESEARCH
(2021)
Article
Engineering, Mechanical
Guizhong Fu, Shukai Jia, Wenbin Zhu, Jiangxin Yang, Yanlong Cao, Michael Ying Yang, Yanpeng Cao
Summary: This paper proposes a multi-light source illumination/acquisition system and a multi-stream CNN model for high-accuracy surface defect classification on highly reflective metal. By fusing features extracted from multi-light source illuminated images, more accurate recognition results can be generated. In addition, the authors also propose individual stream deep supervision and channel attention-based feature re-calibration techniques.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2022)
Article
Evolutionary Biology
Theo Llewellyn, Reuben W. Nowell, Andre Aptroot, Marina Temina, Thomas A. K. Prescott, Timothy G. Barraclough, Ester Gaya
Summary: Fungi produce a large number of secondary metabolites that affect their interactions with other organisms and the environment. Understanding the genes involved in metabolite synthesis is important for studying fungal evolution and adaptation. By using metagenomic sequencing, researchers identified unique transporter genes in a diverse order of lichens that may explain the abundance and ubiquity of UV-protectant secondary metabolites in these lichens. The results highlight the significance of metagenomics in studying the secondary metabolism of non-model fungi like lichens.
GENOME BIOLOGY AND EVOLUTION
(2023)
Article
Multidisciplinary Sciences
Quentin A. Hall, Daniel M. Coffey, Matthew K. Streich, Mark R. Fisher, Gregory W. Stunz
Summary: The text discusses the decline of Southern Flounder populations and the limitations of current angler-intercept creel surveys in monitoring nighttime flounder gigging activity, highlighting the need for more accurate catch and effort estimates.
Article
Astronomy & Astrophysics
Joshua T. Briegal, Edward Gillen, Didier Queloz, Simon Hodgkin, Jack S. Acton, David R. Anderson, David J. Armstrong, Matthew P. Battley, Daniel Bayliss, Matthew R. Burleigh, Edward M. Bryant, Sarah L. Casewell, Jean C. Costes, Philipp Eigmuller, Samuel Gill, Michael R. Goad, Maximilian N. Gunther, Beth A. Henderson, James A. G. Jackman, James S. Jenkins, Lars T. Kreutzer, Maximiliano Moyano, Monika Lendl, Gareth D. Smith, Rosanna H. Tilbrook, Christopher A. Watson, Richard G. West, Peter J. Wheatley
Summary: In this study, we analysed over 829,481 stars using data from the Next Generation Transit Survey (NGTS) to extract their variability periods. By comparing the extracted periods with stellar parameters from Gaia DR2, we were able to identify distinct regions of variability in the Hertzsprung-Russell Diagram. We also observed variable signals associated with various astrophysical phenomena and discovered a dearth of rotation periods in a specific range, which had previously only been seen in space-based observations.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2022)
Review
Endocrinology & Metabolism
G. A. Fitzgerald, G. Yang, G. K. Paschos, X. Liang, C. Skarke
DIABETES OBESITY & METABOLISM
(2015)
Article
Multidisciplinary Sciences
Anne M. Curtis, Caio T. Fagundes, Guangrui Yang, Eva M. Palsson-McDermott, Paulina Wochal, Anne F. McGettrick, Niamh H. Foley, James O. Early, Lihong Chen, Hanrui Zhang, Chenyi Xue, Sarah S. Geiger, Karsten Hokamp, Muredach P. Reilly, Andrew N. Coogan, Elena Vigorito, Garret A. FitzGerald, Luke A. J. O'Neill
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2015)
Editorial Material
Pharmacology & Pharmacy
Guangrui Yang, Han Wang, Erquan Zhang
FRONTIERS IN PHARMACOLOGY
(2015)
Review
Pharmacology & Pharmacy
Lihong Chen, Guangrui Yang
FRONTIERS IN PHARMACOLOGY
(2015)
Review
Cell Biology
Guangrui Yang, Lihong Chen
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2016)
Article
Cell Biology
Guangrui Yang, Lihong Chen, Gregory R. Grant, Georgios Paschos, Wen-Liang Song, Erik S. Musiek, Vivian Lee, Sarah C. McLoughlin, Tilo Grosser, George Cotsarelis, Garret A. FitzGerald
SCIENCE TRANSLATIONAL MEDICINE
(2016)
Article
Gastroenterology & Hepatology
Ying Sun, Zhanjun Jia, Guangrui Yang, Yutaka Kakizoe, Mi Liu, Kevin T. Yang, Ying Liu, Baoxue Yang, Tianxin Yang
JOURNAL OF HEPATOLOGY
(2014)
Article
Hematology
Guangrui Yang, Jiayang Zhang, Tingting Jiang, James Monslow, Soon Yew Tang, Leslie Todd, Ellen Pur, Lihong Chen, Garret A. FitzGerald
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2020)
Article
Peripheral Vascular Disease
Chuanming Xu, Guangrui Yang, Ziwei Fu, Yanting Chen, Shiying Xie, Fei Wang, Tianxin Yang
Summary: This study found that the CD COX-2/EP1 pathway may play an important role in maintaining Na+ homeostasis during Na+ depletion, at least in part, through activation of the intrarenal renin-angiotensin-aldosterone system and epithelial sodium channel.
Article
Nutrition & Dietetics
Baoyin Ren, Yingzhi Huang, Jiayang Zhang, Jiazhi Li, Zhaiyi Liu, Youfei Guan, Lihong Chen, Guangrui Yang
Summary: Time-restricted feeding (TRF) has been shown to alleviate circadian disruption, especially in the case of jet lag in mice, with beneficial effects in certain situations.
Article
Psychology, Biological
Changxiao Ma, Baoyin Ren, Lihong Chen, Guangrui Yang
Summary: The mammalian circadian system has plasticity and considerable variations among species, strains, and ages. This study investigated the entrainable range of circadian behavior in two popular mouse strains and suggested that behavioral adaptation may not well reflect their health status.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Biochemistry & Molecular Biology
Chengcheng Liu, Shuyao Li, Shuang Ji, Jiayang Zhang, Feng Zheng, Youfei Guan, Guangrui Yang, Lihong Chen
Summary: Recent studies have shown that the core clock gene Bmal1 plays a significant role in renal physiological functions. This study found that deletion of Bmal1 in the proximal tubule exacerbated chronic kidney disease (CKD) and renal fibrosis. Mechanistically, Bmal1 regulates fatty acid oxidation and glutathione metabolism, and activates the transcription of CBS to stimulate glutathione biosynthesis. These findings provide a potential target for treating CKD.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2023)
Article
Gastroenterology & Hepatology
Zhaiyi Liu, Jiayang Zhang, Shuyao Li, Hui Wang, Baoyin Ren, Jiazhi Li, Zhiyue Bao, Jiaxin Liu, Meina Guo, Guangrui Yang, Lihong Chen
Summary: This study reveals a critical role of the Bmal1-Junb-AKT/ERK axis in the circadian control of ConA-induced hepatitis, providing new insights into the prevention and treatment of immune-mediated hepatitis, including autoimmune hepatitis (AIH). The findings have scientific implications as they enhance our understanding of the circadian regulation of immune responses in liver diseases.
Article
Immunology
Zhaiyi Liu, Zhiyue Bao, Bo Yu, Lihong Chen, Guangrui Yang
Summary: This study demonstrates that Pemetrexed (PEM) effectively alleviates immune-mediated hepatic injuries by inhibiting M1 macrophage activation through the NF-kappa B signaling pathways. It significantly improves mouse survival rates and reduces serum transaminase levels. Additionally, PEM also mitigates oxidative stress, reduces histopathological liver damage, and decreases hepatocyte apoptosis. Furthermore, PEM decreases the expression of proinflammatory cytokines and genes associated with M1 macrophages in the liver.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Article
Medicine, Research & Experimental
Guangrui Yang, Lihong Chen, Jiayang Zhang, Baoyin Ren, Garret A. Fitzgerald
