Puma Deletion Delays Cardiac Dysfunction in Murine Heart Failure Models Through Attenuation of Apoptosis

Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance

(2010) Russell S. Whelan et al.   Annual Review of Physiology

Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia

(2010) J. Long et al.   BLOOD

MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity

(2010) Manujendra N. Saha et al.   CANCER BIOLOGY & THERAPY

Molecular Mechanisms of Cardiovascular Toxicity of Targeted Cancer Therapeutics

(2010) Hui Cheng et al.   CIRCULATION RESEARCH

Apoptosis predominates in nonmyocytes in heart failure

(2009) Misun Park et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP

(2009) Craig W. Younce et al.   BIOCHEMICAL JOURNAL

ASK1 Regulates Cardiomyocyte Death but Not Hypertrophy in Transgenic Mice

(2009) Qinghang Liu et al.   CIRCULATION RESEARCH

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L

(2009) G W Dorn et al.   ONCOGENE

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy

(2008) E. J. Birks et al.   CARDIOVASCULAR RESEARCH

Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation

(2008) Abhinav Diwan et al.   CIRCULATION

Acute Doxorubicin Cardiotoxicity Is Associated With p53-Induced Inhibition of the Mammalian Target of Rapamycin Pathway

(2008) Wuqiang Zhu et al.   CIRCULATION

An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival

(2008) Elizabeth Yee-Wai Choy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mdm2 and Mdm4 Loss Regulates Distinct p53 Activities

(2008) J. A. Barboza et al.   MOLECULAR CANCER RESEARCH

Cardiac Plasticity

(2008) Joseph A. Hill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload

(2008) J. A. Muraski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA