Recent advances in brown adipose tissue biology

BMP-9 as a potent brown adipogenic inducer with anti-obesity capacity

(2014) Mario Meng-Chiang Kuo et al.   BIOMATERIALS

Brown adipose tissue activity after a high-calorie meal in humans

(2013) Maarten J Vosselman et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

An endocrine role for brown adipose tissue?

(2013) Joan Villarroya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Browning of white adipose tissue: role of hypothalamic signaling

(2013) Sheng Bi et al.   Annals of the New York Academy of Sciences

Brown adipose tissue transplantation improves whole-body energy metabolism

(2013) Xiaomeng Liu et al.   CELL RESEARCH

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

MiR-27 orchestrates the transcriptional regulation of brown adipogenesis

(2013) Lei Sun et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch

(2013) Jiqiu Wang et al.   NATURE CELL BIOLOGY

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

(2013) Shu-Wen Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brown adipose tissue functions in humans

(2012) Kirsi A. Virtanen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Production of Functional Classical Brown Adipocytes from Human Pluripotent Stem Cells using Specific Hemopoietin Cocktail without Gene Transfer

(2012) Miwako Nishio et al.   Cell Metabolism

Brown adipose tissue and the regulation of nonshivering thermogenesis

(2012) Wouter van Marken Lichtenbelt   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway

(2012) Kristy L. Townsend et al.   FASEB JOURNAL

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

(2012) Kristin I. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans

(2012) Véronique Ouellet et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

(2012) Marica Bordicchia et al.   JOURNAL OF CLINICAL INVESTIGATION

The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes

(2012) A. Vitali et al.   JOURNAL OF LIPID RESEARCH

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Cold but not sympathomimetics activates human brown adipose tissue in vivo

(2012) A. M. Cypess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells

(2012) Masaki Mori et al.   PLOS BIOLOGY

Central circuitries for body temperature regulation and fever

(2011) Kazuhiro Nakamura   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Implication of Brown Adipose Tissue for Humans

(2011) Eric Ravussin et al.   Annual Review of Nutrition

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

(2011) Janne Orava et al.   Cell Metabolism

Orexin Is Required for Brown Adipose Tissue Development, Differentiation, and Function

(2011) Dyan Sellayah et al.   Cell Metabolism

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

(2011) M. Castillo et al.   DIABETES

Renaissance of Brown Adipose Tissue

(2011) D. Tews et al.   Hormone Research in Paediatrics

Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

(2011) Elayne Hondares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Dionysios Chartoumpekis et al.   MOLECULAR MEDICINE

Mir193b–365 is essential for brown fat differentiation

(2011) Lei Sun et al.   NATURE CELL BIOLOGY

Brown adipose tissue activity controls triglyceride clearance

(2011) Alexander Bartelt et al.   NATURE MEDICINE

Adipose Inflammation Initiates Recruitment of Leukocytes to Mouse Femoral Artery: Role of Adipo-Vascular Axis in Chronic Inflammation

(2011) Sumihiko Hagita et al.   PLoS One

Brown fat as a therapy for obesity and diabetes

(2011) Aaron M Cypess et al.   Current Opinion in Endocrinology Diabetes and Obesity

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

(2010) G. Barbatelli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brain-derived neurotrophic factor (BDNF) in the hypothalamic ventromedial nucleus increases energy expenditure

(2010) ChuanFeng Wang et al.   BRAIN RESEARCH

Molecular Aspects of Thyroid Hormone Actions

(2010) Sheue-Yann Cheng et al.   ENDOCRINE REVIEWS

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular bioenergetics as a target for obesity therapy

(2010) Yu-Hua Tseng et al.   NATURE REVIEWS DRUG DISCOVERY

Body Fat Distribution and Inflammation Among Obese Older Adults With and Without Metabolic Syndrome

(2010) Annemarie Koster et al.   Obesity

Brown Adipose Tissue, Whole-Body Energy Expenditure, and Thermogenesis in Healthy Adult Men

(2010) Takeshi Yoneshiro et al.   Obesity

UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity

(2010) Lise Madsen et al.   PLoS One

Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

(2010) A. Vegiopoulos et al.   SCIENCE

Three Members of the Iodothyronine Deiodinase Family,dio1,dio2anddio3, are Expressed in Spatially and Temporally Specific Patterns During Metamorphosis of the Flounder,Paralichthys olivaceus

(2010) Kae Itoh et al.   ZOOLOGICAL SCIENCE

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism

(2009) Tim J. Schulz et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Transcriptional control of brown adipocyte development and physiological function--of mice and men

(2009) P. Seale et al.   GENES & DEVELOPMENT

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex

(2009) Shingo Kajimura et al.   NATURE

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

(2009) H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism

(2008) Thien T. Tran et al.   Cell Metabolism

Molecular determinants of brown adipocyte formation and function

(2008) S. R. Farmer   GENES & DEVELOPMENT

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

A Reservoir of Brown Adipocyte Progenitors in Human Skeletal Muscle

(2008) Mihaela Crisan et al.   STEM CELLS

Thyroid–Adrenergic Interactions: Physiological and Clinical Implications

(2008) J. Enrique Silva et al.   THYROID