The Implication of Brown Adipose Tissue for Humans

A critical appraisal of the prevalence and metabolic significance of brown adipose tissue in adult humans

(2010) Paul Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Human Brown Adipose Tissue

(2010) Sven Enerbäck   Cell Metabolism

Brown Fat and the Myth of Diet-Induced Thermogenesis

(2010) Leslie P. Kozak   Cell Metabolism

The Changed Metabolic World with Human Brown Adipose Tissue: Therapeutic Visions

(2010) Jan Nedergaard et al.   Cell Metabolism

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease

(2010) Daniel J. Ho et al.   EXPERIMENTAL NEUROLOGY

A missing link in the puzzle: Brown adipose tissue

(2010) Tugrul Purnak et al.   HEPATOLOGY

Leptin Replacement Prevents Weight Loss-Induced Metabolic Adaptation in Congenital Leptin-Deficient Patients

(2010) Jose E. Galgani et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

Cellular bioenergetics as a target for obesity therapy

(2010) Yu-Hua Tseng et al.   NATURE REVIEWS DRUG DISCOVERY

Brown adipose tissue—a new role in humans?

(2010) Martin E. Lidell et al.   Nature Reviews Endocrinology

Transplantation of adipose tissue and stem cells: role in metabolism and disease

(2010) Thien T. Tran et al.   Nature Reviews Endocrinology

Cold-Induced Adaptive Thermogenesis in Lean and Obese

(2010) Sander L.J. Wijers et al.   Obesity

Perspective: Does brown fat protect against diseases of aging?

(2009) Mark P. Mattson   AGEING RESEARCH REVIEWS

Transdifferentiation properties of adipocytes in the adipose organ

(2009) Saverio Cinti   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A New Twist on Brown Fat Metabolism

(2009) Harriet Wallberg-Henriksson et al.   CELL

Twist-1 Is a PPARδ-Inducible, Negative-Feedback Regulator of PGC-1α in Brown Fat Metabolism

(2009) Dongning Pan et al.   CELL

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Brown Adipose Tissue and Seasonal Variation in Humans

(2009) I. T.H. Au-Yong et al.   DIABETES

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

(2009) Maria Cristina Zingaretti et al.   FASEB JOURNAL

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C/EBP  and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor   Agonists

(2009) C. Vernochet et al.   MOLECULAR AND CELLULAR BIOLOGY

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex

(2009) Shingo Kajimura et al.   NATURE

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Have we entered the brown adipose tissue renaissance?

(2009) E. Ravussin et al.   Obesity Reviews

Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss

(2009) Leanne M. Redman et al.   PLoS One

The Efficiency of Cellular Energy Transduction and Its Implications for Obesity

(2008) Mary-Ellen Harper et al.   Annual Review of Nutrition

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

Quantitative Assessment of FDG Uptake in Brown Fat Using Standardized Uptake Value and Dual-Time-Point Scanning

(2008) Khaled Alkhawaldeh et al.   CLINICAL NUCLEAR MEDICINE

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

(2008) S. Kajimura et al.   GENES & DEVELOPMENT

Inactivation of UCP1 and the Glycerol Phosphate Cycle Synergistically Increases Energy Expenditure to Resist Diet-induced Obesity

(2008) Rea Anunciado-Koza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct expression of muscle-specific MicroRNAs (myomirs) in brown adipocytes

(2008) Tomas B. Walden et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Functional Interaction between RIP140 and PGC-1  Regulates the Expression of the Lipid Droplet Protein CIDEA

(2008) M. Hallberg et al.   MOLECULAR AND CELLULAR BIOLOGY

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1 

(2008) A. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Reservoir of Brown Adipocyte Progenitors in Human Skeletal Muscle

(2008) Mihaela Crisan et al.   STEM CELLS