Copper(I)-Catalyzed Azide-Alkyne Cycloadditions in Microflow: Catalyst Activity, High-T Operation, and an Integrated Continuous Copper Scavenging Unit

Potenzialanalyse von Milli- und Mikroprozesstechniken für die Verkürzung von Prozessentwicklungszeiten - Chemie und Prozessdesign als Intensivierungsfelder

(2012) Volker Hessel et al.   CHEMIE INGENIEUR TECHNIK

Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator

(2012) Albert E. Cervera-Padrell et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Accelerating Palladium-Catalyzed CF Bond Formation: Use of a Microflow Packed-Bed Reactor

(2011) Timothy Noël et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Suzuki-Miyaura Cross-Coupling Reactions in Flow: Multistep Synthesis Enabled by a Microfluidic Extraction

(2011) Timothy Noël et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

(2011) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals

(2011) Javier Magano et al.   CHEMICAL REVIEWS

Cross-coupling in flow

(2011) Timothy Noël et al.   CHEMICAL SOCIETY REVIEWS

The importance of Green Chemistry in Process Research and Development

(2011) Peter J. Dunn   CHEMICAL SOCIETY REVIEWS

Bis(diethylamino)(pentafluorophenyl)phosphane - a Push-Pull Phosphane Available for Coordination

(2011) Andreas Orthaber et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes

(2011) Dong Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Suzuki–Miyaura Cross-Coupling of Heteroaryl Halides and Arylboronic Acids in Continuous Flow

(2011) Timothy Noël et al.   ORGANIC LETTERS

Synthesis of 5-Iodo-1,2,3-triazole-Containing Macrocycles Using Copper Flow Reactor Technology

(2011) Andrew R. Bogdan et al.   ORGANIC LETTERS

Mechanistic Insights into Copper(I)-Catalyzed Azide-Alkyne Cycloadditions using Continuous Flow Conditions

(2010) Michael Fuchs et al.   ADVANCED SYNTHESIS & CATALYSIS

Novel process windows – Concept, proposition and evaluation methodology, and intensified superheated processing

(2010) Volker Hessel et al.   CHEMICAL ENGINEERING SCIENCE

Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(i) acetylides

(2010) Jason E. Hein et al.   CHEMICAL SOCIETY REVIEWS

Efficient Access to New Chemical Space Through Flow-Construction of Druglike Macrocycles Through Copper-Surface-Catalyzed Azide-Alkyne Cycloaddition Reactions

(2010) Andrew R. Bogdan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Heterogeneous catalytic synthesis using microreactor technology

(2010) Christopher G. Frost et al.   GREEN CHEMISTRY

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

The Use of Copper Flow Reactor Technology for the Continuous Synthesis of 1,4-Disubstituted 1,2,3-Triazoles

(2009) Andrew R. Bogdan et al.   ADVANCED SYNTHESIS & CATALYSIS

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistep Microchemical Synthesis Enabled by Microfluidic Distillation

(2009) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Accessing Novel Process Windows in a High-Temperature/Pressure Capillary Flow Reactor

(2009) T. Razzaq et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Novel Process Windows - Gate to Maximizing Process Intensification via Flow Chemistry

(2009) V. Hessel   CHEMICAL ENGINEERING & TECHNOLOGY

Click chemistry under non-classical reaction conditions

(2009) C. Oliver Kappe et al.   CHEMICAL SOCIETY REVIEWS

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Sustainability through green processing – novel process windows intensify micro and milli process technologies

(2008) Volker Hessel et al.   Energy & Environmental Science