Efficient Access to New Chemical Space Through Flow-Construction of Druglike Macrocycles Through Copper-Surface-Catalyzed Azide-Alkyne Cycloaddition Reactions

Mechanistic Insights into Copper(I)-Catalyzed Azide-Alkyne Cycloadditions using Continuous Flow Conditions

(2010) Michael Fuchs et al.   ADVANCED SYNTHESIS & CATALYSIS

The Flow’s the Thing…︁Or Is It? Assessing the Merits of Homogeneous Reactions in Flask and Flow

(2010) Fernando E. Valera et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tricks with clicks: modification of peptidomimetic oligomers via copper-catalyzed azide-alkyne [3 + 2] cycloaddition

(2010) Justin M. Holub et al.   CHEMICAL SOCIETY REVIEWS

Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(i) acetylides

(2010) Jason E. Hein et al.   CHEMICAL SOCIETY REVIEWS

Targeting the Hsp90 Chaperone: Synthesis of Novel Resorcylic Acid Macrolactone Inhibitors of Hsp90

(2010) James E. H. Day et al.   CHEMISTRY-A EUROPEAN JOURNAL

Unsupported Copper Nanoparticles in the 1,3-Dipolar Cycloaddition of Terminal Alkynes and Azides

(2010) Francisco Alonso et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Use of Copper Flow Reactor Technology for the Continuous Synthesis of 1,4-Disubstituted 1,2,3-Triazoles

(2009) Andrew R. Bogdan et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper(I)-Catalyzed Cycloaddition of Organic Azides and 1-Iodoalkynes

(2009) Jason E. Hein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Modular Approach to Functionalized and Expanded Crown Ether Based Macrocycles Using Click Chemistry

(2009) Sandra Binauld et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Green Chemistry: Principles and Practice

(2009) Paul Anastas et al.   CHEMICAL SOCIETY REVIEWS

Propargyl Amine Synthesis Catalysed by Gold and Copper Thin Films by Using Microwave-Assisted Continuous-Flow Organic Synthesis (MACOS)

(2009) Gjergji Shore et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemoenzymatic Synthesis of a New Class of Macrocyclic Oligosaccharides

(2009) Saddam Muthana et al.   JOURNAL OF ORGANIC CHEMISTRY

Microchemical systems for continuous-flow synthesis

(2009) Ryan L. Hartman et al.   LAB ON A CHIP

Synthesis, molecular docking and biological evaluation as HDAC inhibitors of cyclopeptide mimetics by a tandem three-component reaction and intramolecular [3+2] cycloaddition

(2009) Tracey Pirali et al.   MOLECULAR DIVERSITY

Accessing Skeletal Diversity Using Catalyst Control: Formation ofnandn+ 1 Macrocyclic Triazole Rings

(2009) Ann Rowley Kelly et al.   ORGANIC LETTERS

Visual Observation of Redistribution and Dissolution of Palladium during the Suzuki–Miyaura Reaction

(2008) Stephanie MacQuarrie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The exploration of macrocycles for drug discovery — an underexploited structural class

(2008) Edward M. Driggers et al.   NATURE REVIEWS DRUG DISCOVERY