Article
Biochemical Research Methods
Alex Glineur, Marco Beccaria, Giorgia Purcaro
Summary: Lowering the ionization energy in GC-MS/MS can significantly increase the sensitivity in detecting estrogenic compounds, leading to a 100-fold lower limit of quantification compared to liquid chromatography-MS/MS and minimal matrix effects. This can potentially aid in the development of a miniaturized sample preparation method to meet the challenging detection limits required by EU regulations.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Energy & Fuels
Xinheng Cai, Rong Shi, Wei Wang, Huandi Hou, Dongyue Peng, Naixin Wang, Zhonghuo Deng, Zelong Liu, Qundan Zhang
Summary: In this study, the fragmentation behaviors of sulfur-containing model compounds were investigated using FT-ICR MS coupled with collision-induced dissociation. The structure differences of sulfur compounds in heavy oils before and after hydrogenation were compared. The results have significant implications for the development of HDS catalyst/process for heavy oils.
Article
Energy & Fuels
Carla Santos de Freitas, Jeferson A. Valencia-Davila, Rosana Cardoso Lopes Pereira, Luiza Torres Abrantes, Lucilia Kato, Boniek Gontijo Vaz
Summary: The study focused on the extraction and fractionation of sulfur-containing compounds from vacuum gas oil using non-reactive methods such as ligand exchange chromatography and molecularly imprinted polymer. Different sorbents and cations were used to isolate specific sulfur compounds, resulting in varying degrees of selectivity and separation efficiency. Further analysis by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization Orbitrap mass spectrometry allowed for the detection of a wider range of sulfur compounds with different degrees of unsaturation.
Article
Biochemical Research Methods
Anika Neumann, Ole Tiemann, Helly J. Hansen, Christopher P. Rueger, Ralf Zimmermann
Summary: In this work, the ionization characteristics of a xenon discharge lamp (Xe-APPI) were studied and compared to established ionization schemes. The Xe-APPI proved efficient in ionizing a broad range of polycyclic aromatic hydrocarbons and their derivatives, but not thiol and ester compounds. It had a high tendency to generate oxygenated artifacts. Compared to other ionization methods, Xe-APPI had almost no chemical background and showed a high selectivity for low alkylated aromatic core structures.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Chemistry, Analytical
A. Arrizabalaga-Larranaga, S. Epigmenio-Chamu, F. J. Santos, E. Moyano
Summary: This paper describes the development of a rapid and sensitive method for detecting banned dyes in spice samples using UHPLC-MS/MS technology combined with three atmospheric pressure ionization sources. The proposed method demonstrated good performance in sample analysis, with low detection limits, good precision, and accurate quantitation.
ANALYTICA CHIMICA ACTA
(2021)
Article
Energy & Fuels
Alessandro Vetere, Daniel Profrock, Wolfgang Schrader
Summary: The article focuses on the molecular analysis of crude oil and its fractions, with a particular emphasis on the challenging task of quantifying sulfur. The proposed method combines sulfur-selective chromatographic separation and mass spectrometry detection for both qualitative and quantitative analysis of sulfur compounds in complex heavy crude oil fractions.
Article
Energy & Fuels
Charlotte Mase, Julien F. Maillard, Benoit Paupy, Mathilde Farenc, Cindy Adam, Marie Hubert-Roux, Carlos Afonso, Pierre Giusti
Summary: Plastic wastes lead to harmful effects on the environment and landfill depletion. Pyrolysis oil produced from plastic waste is deemed an important source for producing monomers, fuels, and chemicals, which helps circumvent environmental concerns associated with nonrenewable fossil resources and address waste disposal issues. High-resolution molecular characterization is essential for understanding the complex composition of plastic pyrolysis oils which are similar to petroleum crude oils, and various ionization techniques such as ESI, APPI, and APCI are used to analyze different types of chemical species present.
Article
Chemistry, Analytical
Fan Huang, Kersti Karu, Luiza C. Campos
Summary: In this study, a modified derivatisation-based methodology combined with liquid chromatography tandem mass spectrometry was successfully applied for the simultaneous determination of estrogens in environmental samples, including various isomers. Optimization of solid phase extraction and enhancement of mass spectrometric signal led to satisfactory recovery and good linearity, demonstrating the repeatability and sensitivity of the method. The established methodology was effectively used to analyze the concentration of estrogens in natural water samples, with three free estrogens and two sulphate estrogens being detected above their method quantification limits.
Review
Chemistry, Analytical
Juan F. Ayala-Cabrera, Lidia Montero, Sven W. Meckelmann, Florian Uteschil, Oliver J. Schmitz
Summary: The use of atmospheric pressure ionization (API) sources in GC-MS analysis has gained popularity due to its advantages over traditional vacuum ionization sources. This review focuses on recent advances in GC-API-MS instrumentation, discussing new setups and couplings, as well as the development of novel API sources. In addition, new ionization strategies are reviewed to overcome drawbacks of GC-API-MS methodologies.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemical Research Methods
Ane Arrizabalaga-Larranaga, Pedro de Juan-de Juan, Claudia Bressan, Mercedes Vazquez-Espinosa, Ana Gonzalez-de-Peredo, F. Javier Santos, Encarnacion Moyano
Summary: This study developed a sensitive and selective UHPLC-MS/MS method for the detection of 23 PAAs, showing the advantage of APCI as an alternative method for the analysis of PAAs. The developed method was applied to the analysis of kitchenware samples, where PAAs concentrations above the legislated limit were detected in 18 out of 20 samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
G. Asher Newsome, Kathleen M. Martin
Summary: This study examines selected Native American woven woodsplint basketry created between 1870 and 1983 to recover traditional knowledge on their manufacture by identifying dyes or colorants. An ambient mass spectrometry system is used to non-invasively sample from intact objects, with no cutting or exposure to liquid. The analysis process involves thermal desorption, gas phase analysis, and photoionization for real-time identification of dye molecules.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Herbert J. Dias, Eduardo J. Crevelin, Vinicius Palaretti, Ricardo Vessecchi, Antonio E. M. Crotti
Summary: Through negative ion ESI accurate-mass tandem and sequential mass spectrometry, it was found that deprotonated DBNs produced more diagnostic product ions than protonated molecules, providing more information and avoiding the use of additives.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Giovanni Vinci, Alessandro Piccolo, Maxime Bridoux
Summary: High resolution mass spectrometry combined with both photoionization and electrospray ionization, as well as humeomic fractionation, increases the identification of molecular composition of soil humus. Different fractions showed distinct molecular characteristics, and the ionization techniques demonstrated selectivity for chemically different molecules. The findings indicate a deeper understanding of the molecular composition of soil humus and its environmental reactivity.
ANALYTICA CHIMICA ACTA
(2022)
Article
Environmental Sciences
J. F. Ayala-Cabrera, C. Lipok, E. Moyano, O. J. Schmitz, F. J. Santos
Summary: In this study, the performance of APCI and APPI were evaluated for the determination of PCNs in sediment samples using GC-HRMS. The comparison of the two API sources led to the selection of GC-APPI(+)-HRMS (Orbitrap) as the most effective method. The method showed great detection capabilities, low method limits of detection, and good precision and trueness for analyzing PCNs in environmental samples.
Article
Environmental Sciences
Hyeon-Jeong Lee, Minsik Kang, Junghyun Son, Hophil Min, Sangwon Cha, Han Bin Oh, Won Keun Oh, Jaeick Lee
Summary: Phenols are important environmental endocrine disruptors with potential adverse health effects. A comprehensive and sensitive analytical method for multiple classes of phenols was developed by investigating the influence of mobile phase compositions in LC-ESI-MS/MS analysis. This method allowed for the concurrent ionization of all phenols and significantly improved the analytical sensitivity for certain phenols.
ENVIRONMENTAL RESEARCH
(2023)
Article
Food Science & Technology
Shi-Han Jian, Pei-Jou Yeh, Chung-Huang Wang, Hsin-Chang Chen, Sung-Fang Chen
JOURNAL OF FOOD AND DRUG ANALYSIS
(2019)
Article
Environmental Sciences
Chia-Huang Chang, Yu-Fang Huang, Pei-Wei Wang, Chun-Hao Lai, Li-Wei Huang, Hsin-Chang Chen, Meng-Han Lin, Winnie Yang, I-Fang Mao, Mei-Lien Chen
Correction
Multidisciplinary Sciences
Charlene Wu, Hsin-Chang Chen, Shu-Ting Chen, Su-Yin Chiang, Kuen-Yuh Wu
Article
Public, Environmental & Occupational Health
Chia-Huang Chang, Pei-Wei Wang, Hai-Wei Liang, Yu-Fang Huang, Li-Wei Huang, Hsin-Chang Chen, Wen-Chi Pan, Meng-Han Lin, Winnie Yang, I-Fang Mao, Mei-Lien Chen
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2019)
Article
Biochemical Research Methods
Han-Ju Chien, Yu-Ting Xue, Hsin-Chang Chen, Kuen-Yuh Wu, Chien-Chen Lai
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2020)
Article
Environmental Sciences
Po-Chin Huang, Alexander Waits, Hsin-Chang Chen, Wan-Ting Chang, Jouni J. K. Jaakkola, Han-Bin Huang
ENVIRONMENT INTERNATIONAL
(2020)
Article
Environmental Sciences
Alexander Waits, Hsin-Chang Chen, Pao-Lin Kuo, Chih-Wen Wang, Han-Bin Huang, Wei-Hsiang Chang, Shu-Fang Shih, Po-Chin Huang
ENVIRONMENTAL RESEARCH
(2020)
Article
Toxicology
Hsiao-Chi Chuang, Hsin-Chang Chen, Pei-Jui Chai, Ho-Tang Liao, Chang-Fu Wu, Chia-Ling Chen, Ming-Kai Jhan, Hui- Hsieh, Kuen-Yuh Wu, Ta-Fu Chen, Tsun-Jen Cheng
PARTICLE AND FIBRE TOXICOLOGY
(2020)
Article
Environmental Sciences
Chia-Huang Chang, Ching-Jung Yu, Jung-Chieh Du, Hsien-Chih Chiou, Jia-Woei Hou, Winnie Yang, Chian-Feng Chen, Hsin-Chang Chen, Ying-Sheue Chen, Betau Hwang, Mei-Lien Chen
Summary: This study reveals a potential link between organophosphate pesticide exposure and ADHD, related to oxidative stress and PON genetic polymorphisms. Children exposed to organophosphate pesticides may have higher levels of DMP and HNE-MA. The PON1 genetic polymorphism is associated with exposure levels and the risk of ADHD.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Po-Keng Cheng, Hsin-Chang Chen, Pao-Lin Kuo, Jung-Wei Chang, Wan-Ting Chang, Po-Chin Huang
Summary: This study investigated the association between oxidative and nitrosative stress and thyroid hormones, finding that an imbalance of oxidative and nitrosative stress may alter thyroid hormone homeostasis during pregnancy, which could affect embryonic and fetal development.
Article
Food Science & Technology
Mei-Lien Chen, Chih-Hsien Chen, Yu-Fang Huang, Hsin-Chang Chen, Jung-Wei Chang
Summary: Photoinitiators used in ultraviolet-cured ink may migrate from food packaging materials into food products. A dietary risk assessment was conducted to quantify the exposure to benzophenone-type photoinitiators and reduce associated uncertainties. The study found that the estimated daily dose of photoinitiators was below the toxicological concern threshold, indicating an acceptable level of cumulative toxicity. However, different results may occur if specific migration limits for unmeasured photoinitiator residues in other foodstuffs are followed.
Article
Environmental Sciences
Hsin-Chang Chen, Jung-Wei Chang, Yi-Chen Sun, Wan-Ting Chang, Po-Chin Huang
Summary: The development of a rapid and accurate analytical method for determining levels of antibacterial agents, plasticizers, and ultraviolet filters in biosamples is crucial for individual exposure assessment. This study developed an ID-UPLC-MS/MS method with SLE pretreatment to determine the levels of four parabens, triclosan, triclocarban, and benzophenone-3 in human urine. The method showed good performance and sensitivity in detecting these chemicals, making it valuable for human biomonitoring.
Article
Multidisciplinary Sciences
Vincent Laiman, Yu-Chun Lo, Hsin-Chang Chen, Tzu-Hsuen Yuan, Ta-Chih Hsiao, Jen-Kun Chen, Ching-Wen Chang, Ting-Chun Lin, Ssu-Ju Li, You-Yin Chen, Didik Setyo Heriyanto, Kian Fan Chung, Kai-Jen Chuang, Kin-Fai Ho, Jer-Hwa Chang, Hsiao-Chi Chuang
Summary: Air pollution is associated with respiratory diseases, and urban air pollution is caused by various sources of emissions. The particles and gases emitted are the main components of air pollution that enter the lungs through respiration. Particulate matter with an aerodynamic diameter of ≤ 2.5 μm (PM2.5) can penetrate deep into the respiratory tract through inhalation and has been suggested as a causative factor for adverse respiratory health. Additionally, the lung harbors a diverse microbial community (microbiome) that maintains normal balance but can be significantly altered in certain circumstances.
Article
Environmental Sciences
Hsiao-Chi Chuang, Yu-Ting Yang, Hsin-Chang Chen, Yaw-Huei Hwang, Kuen-Yuh Wu, Ta-Fu Chen, Chia-Ling Chen, Ming-Kai Jhan, Tsun-Jen Cheng
AEROSOL AND AIR QUALITY RESEARCH
(2020)
Article
Chemistry, Multidisciplinary
Perng Yang Puah, Dexter Jiunn Herng Lee, Ken Hing Mak, Hui Jun Ang, Hsing-Chang Chen, Pak Yan Moh, Siat Yee Fong, Yee Soon Ling
