Article
Chemistry, Multidisciplinary
Hyejin Kwon, Brian S. Newell, Carson J. Bruns
Summary: Cycloparaphenylene nanocarbons (CPPs) are organic semiconductors with controllable structures and unique optoelectronic properties. In this study, CH-pi interactions were found to enable the inclusion of redox-active metallocene guests in CPPs, enhancing stability through additional supramolecular forces. This finding is significant for the design of bespoke nanoelectronics and artificial molecular machines.
Article
Chemistry, Multidisciplinary
Maura Malinska
Summary: Crystallization conditions were screened for producing crystal structures of p-tert-butylcalix[6]arene (TBC6) with different conformations, revealing molecular recognition and self-assembly between TBC6 and pyridine leading to various complexes. The crystal structure can be tuned by changing temperature and supersaturation conditions, with the ability to recrystallize as new complexes under thermodynamic conditions. Energy framework analysis was used to study the hierarchies of various interactional motifs and their topologies in the TBC6 complexes.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Chemistry, Organic
Francesco Rispoli, Emanuele Spatola, Daniele Del Giudice, Roberta Cacciapaglia, Alessandro Casnati, Laura Baldini, Stefano Di Stefano
Summary: The interaction between a specific receptor and a chemical fuel can drive the host-guest interaction, leading to the host releasing and reuptaking the guest, with the process being able to be repeated multiple times.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Sangmin Lee, Thi Vo, Sharon C. Glotzer
Summary: In this study, hard truncated triangular bipyramids self-assemble into seven different colloidal clathrate crystals, consisting of cages that are either empty or occupied by guest particles. Monte Carlo simulations reveal that the crystallization occurs through the compartmentalization of entropy between low- and high-entropy subsystems for the host and guest particles. The researchers also use entropic bonding theory to design host-guest colloidal clathrates with explicit interparticle attraction for experimental realization.
Article
Chemistry, Physical
Binh Minh Nguyen, Markus Schmid, Johann Kirsch, Albin Cakaj, Wolfgang Bruetting
Summary: The orientation mechanism of nonpolar dyes in various conditions is studied. It is found that the shape anisotropy and temperature ratio are key factors controlling dye alignment. It is also noted that caution must be exercised when using mixed cohost systems with different glass transition temperatures, as the emitter orientation may not follow the effective glass transition temperature of the mixed host.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Medicinal
Xiao Liu, Lei Zheng, Chu Qin, Yang Li, John Z. H. Zhang, Zhaoxi Sun
Summary: End-point free-energy methods are widely recognized as a tool with certain screening power in pharmaceutical research. However, there is currently a lack of large-scale benchmarks in host-guest complexes to support the screening power of these methods. In this study, a large dataset of 154 host-guest pairs is constructed, and extensive end-point sampling is performed using various free-energy techniques to estimate the free energy.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2023)
Editorial Material
Physics, Multidisciplinary
Michelle D. Wang
Summary: The unit length of DNA is a base pair, which serves as a ruler for DNA compaction and processing, as explained by Michelle Wang.
Article
Biochemical Research Methods
Yun Zhang, Yakun Yi, Ziyi Li, Ke Zhou, Lei Liu, Hai-Chen Wu
Summary: In this paper, an alternative method for peptide sequencing based on enzymatic cleavage and host-guest interaction-assisted nanopore sensing is proposed. Through current blockage during peptide translocation, the identity and sequence of amino acids can be determined. This study demonstrates the potential of nanopore-based protein sequencing.
Article
Chemistry, Multidisciplinary
Xinling Lu, Hui Xu, Yue Cheng, Wei Liu, Yong Wang
Summary: A switchable and versatile separation strategy using reversible supramolecular host-guest interactions has been developed to achieve universal separation. This method offers the ability to selectively separate different substrates, including chiral or achiral molecules, leading to satisfactory single-column universality.
Review
Chemistry, Multidisciplinary
Yun-Fang Zhang, Fang-Fang Di, Peng-Fei Li, Ren-Gen Xiong
Summary: In recent years, molecular ferroelectrics based on crown ethers have attracted attention due to their host-guest structure, which allows for easy order-disorder transitions and induction of ferroelectric phase transitions. The research focus is on the crystal structure, phase transitions, and ferroelectric properties of crown ether host-guest molecular ferroelectrics.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Review
Chemistry, Multidisciplinary
Yun-Fang Zhang, Fang-Fang Di, Peng-Fei Li, Ren-Gen Xiong
Summary: This review summarizes the research progress of crown ether host-guest molecular ferroelectrics, focusing on their crystal structure, phase transition, and ferroelectric-related properties. The article also outlines chemical design strategies for obtaining high-performance crown-ether-based molecular ferroelectrics. It provides guidance for the future exploration of crown ether host-guest molecular ferroelectrics.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Review
Chemistry, Inorganic & Nuclear
Xi Yang, Di Yuan, Jinhong Hou, Adam C. Sedgwick, Suying Xu, Tony D. James, Leyu Wang
Summary: The field of supramolecular chemistry has rapidly expanded and become highly influential in various areas like biomedicine, energy materials, catalysis, and sensing. The combination of host/guest chemistry with functional inorganic nanoparticles has led to many new applications in drug delivery, bioimaging, and sensing. Recent progress in the development of organic/inorganic supramolecular nano-systems incorporating host/guest chemistry has been summarized, highlighting their applications in drug delivery, biological imaging, and sensing.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Thomas A. Sobiech, Yulong Zhong, Daniel P. Miller, Jillian K. McGrath, Christina T. Scalzo, Morgan C. Redington, Eva Zurek, Bing Gong
Summary: The article presents experimental results on the binding of a rigid aromatic oligoamide macrocycle with DABCO-based cationic guests in highly polar DMF, demonstrating strong positive cooperativity. The unusually strong positive cooperativity mechanism is verified through various experimental methods. This host-guest system provides a tunable platform for studying molecular interactions and constructing stable supramolecular assemblies due to its exceptional positive cooperativity.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Sergey Titov, Vitaly G. Avakyan
Summary: The method of molecular dynamics was used to model crystal structures based on dimers and trimers of beta-cyclodextrin containing luminescent complexes. A novel technique was developed to construct these crystals. The obtained structures are stable and allow for the explanation of the observable luminescence properties. This technique is promising for the prediction of new crystal structures and obtaining important supramolecular crystals.
Article
Chemistry, Multidisciplinary
Yang Xia, Chenfei Zhu, Feng Cao, Yunxia Shen, Mi Ouyang, Yujian Zhang
Summary: This study proposes a host-guest doping strategy to achieve both room-temperature phosphorescence (RTP) and flexibility in organic single crystals (OSCs). The flexible OSCs exhibit bright deep-red phosphorescence upon external force application and can return to their original shape after stress removal. The results suggest that the bright RTP is due to Forster resonance energy transfer (FRET) from the triphenylene molecules to the dopants. This strategy provides a simple and universal approach for the preparation of flexible OSCs with RTP.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)