Reversible and Efficient Inhibition of UDP-Galactopyranose Mutase by Electrophilic, Constrained and Unsaturated UDP-Galactitol Analogues

Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation

(2012) Richa Dhatwalia et al.   BIOCHEMISTRY

Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic FungusAspergillus fumigatus

(2012) Richa Dhatwalia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase fromAspergillus fumigatus

(2012) Karin E. van Straaten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Mechanism of UDP-Galactopyranose Mutase from Trypanosoma cruzi: A Potential Drug Target against Chagas' Disease

(2012) Michelle Oppenheimer et al.   PLoS One

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase

(2011) He G. Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Remarkable Stereospecific Conjugate Additions to the Hsp90 Inhibitor Celastrol

(2011) Lada Klaić et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome Mining inStreptomyces. Discovery of an Unprecedented P450-Catalyzed Oxidative Rearrangement That Is the Final Step in the Biosynthesis of Pentalenolactone

(2011) Dongqing Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus

(2010) Michelle Oppenheimer et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Synthetic UDP-Furanoses as Potent Inhibitors of Mycobacterial Galactan Biogenesis

(2010) Pauline Peltier et al.   CHEMISTRY & BIOLOGY

Antimycobacterial activity of UDP-galactopyranose mutase inhibitors

(2010) Silvia Borrelli et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase

(2010) Sarathy Karunan Partha et al.   JOURNAL OF MOLECULAR BIOLOGY

Michael Acceptor-Containing Coenzyme A Analogues As Inhibitors of the Atypical Coenzyme A Disulfide Reductase fromStaphylococcus aureus

(2010) Renier van der Westhuyzen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray Crystallography Reveals a Reduced Substrate Complex of UDP-Galactopyranose Mutase Poised for Covalent Catalysis by Flavin,

(2009) Todd D. Gruber et al.   BIOCHEMISTRY

Chemistry and Biology of Galactofuranose-Containing Polysaccharides

(2009) Michele R. Richards et al.   CHEMBIOCHEM

Recent advances in mycobacterial cell wall glycan biosynthesis

(2009) Pui-Hang Tam et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis of ThreeC-Glycoside Analogues of UDP-Galactopyranose as Conformational Probes for the Mutase-Catalyzed Furanose/Pyranose Interconversion

(2009) Audrey Caravano et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Characterization of a Bifunctional Pyranose-Furanose Mutase fromCampylobacter jejuni11168

(2009) Myles B. Poulin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ligand Binding and Substrate Discrimination by UDP-Galactopyranose Mutase

(2009) Todd D. Gruber et al.   JOURNAL OF MOLECULAR BIOLOGY

O-GlcNAc Peptide Epoxyketones Are Recognized by Mammalian Proteasomes

(2009) Martin D. Witte et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sugar nucleotide recognition by Klebsiella pneumoniae UDP-d-galactopyranose mutase: Fluorinated substrates, kinetics and equilibria

(2009) James C. Errey et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

On the synthesis of vinyl and phenyl C-furanosides by stereospecific debenzylative cycloetherification

(2009) Riccardo Cribiù et al.   TETRAHEDRON

Probing UDP-galactopyranose mutase binding pocket: A dramatic effect on substitution of the 6-position of UDP-galactofuranose

(2008) Guillaume Eppe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent knowledge and innovations related to hexofuranosides: structure, synthesis and applications

(2008) Pauline Peltier et al.   CARBOHYDRATE RESEARCH

Stereospecific debenzylative cycloetherification of carbohydrate-derived allylic alcohols, ethers and esters to form vinyl C-furanosides

(2008) Riccardo Cribiù et al.   CHEMICAL COMMUNICATIONS

Convergent and Stereoselective Synthesis of Iminosugar-Containing Galfand UDP-GalfMimicks:  Evaluation as Inhibitors of UDP-Gal Mutase

(2008) Virginie Liautard et al.   JOURNAL OF ORGANIC CHEMISTRY

Investigation of Binding of UDP-Galfand UDP-[3-F]Galfto UDP-galactopyranose Mutase by STD-NMR Spectroscopy, Molecular Dynamics, and CORCEMA-ST Calculations†

(2008) Yue Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibitors of UDP-Galactopyranose Mutase Thwart Mycobacterial Growth

(2008) Emily C. Dykhuizen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Potent Ligands for Prokaryotic UDP-Galactopyranose Mutase That Exploit an Enzyme Subsite

(2008) Emily C. Dykhuizen et al.   ORGANIC LETTERS

Substrate directs enzyme dynamics by bridging distal sites: UDP-galactopyranose mutase

(2008) Xiaohui Yao et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS