Article
Chemistry, Applied
Linlin Fan, Qihe Chen, Yasheng Mairiyangu, Ying Wang, Xiaoli Liu
Summary: The study showed that stable vesicles formulated with MEL-A and PC in different ratios exhibited varying sizes and encapsulation efficiencies. These vesicles successfully encapsulated anthocyanins and displayed higher retention rates under storage and simulated gastrointestinal fluid conditions.
Article
Polymer Science
Ha Pham Le Khanh, Adam Haimhoffer, Daniel Nemes, Liza Jozsa, Gabor Vasvari, Istvan Budai, Attila Benyei, Zoltan Ujhelyi, Palma Feher, Ildiko Bacskay
Summary: Solid dispersions consist of a hydrophilic matrix polymer and a lipophilic active substance, and the drug undergoes a phase transition during formulation, leading to a supersaturated solution. The interaction between the active substance and the polymer affects the level of supersaturation. In this study, we investigated the effect of molecular weight on the relationship between low molecular weight polyethylene glycol derivates and ketoprofen. The results showed that the molecular weight had limited impact on the physicochemical characteristics and interactions, suggesting the need for further investigation to select the most suitable candidate.
Article
Chemistry, Applied
Laura Hanley, Saeed M. Ghazani, Alejandro G. Marangoni
Summary: The spontaneous formation of phospholipid vesicles was explored for the production of liposomal encapsulations of bioactive compounds. Stable vesicles were produced from unrefined soybean and sunflower lecithin, and their structure and encapsulation capacity were evaluated. These vesicles demonstrated high thermal and oxidative stability, making them suitable for food applications.
Article
Chemistry, Applied
Milad Jafarpour, Milad Fathi, Nafiseh Soltanizadeh
Summary: Encapsulated PCM has been developed for thermal buffering in food packaging. The encapsulated PEG exhibited decreased crystallization temperature and melting enthalpy. The encapsulation process improved the thermal stability of PCM. Encapsulated PCM was effective in controlling temperature fluctuation and preserving the quality of perishable food.
FOOD HYDROCOLLOIDS
(2023)
Article
Biology
Ke Zhen, Xiaojuan Wei, Zelun Zhi, Shuyan Zhang, Liujuan Cui, Yue Li, Xia Chen, Jing Yao, Hongchao Zhang
Summary: This study compared three different methods for isolating extracellular vesicles and found that size exclusion chromatography (SEC) had high yield and low contamination, making it an ideal method for isolating extracellular vesicles from the plasma of patients with hyperlipidemia.
Article
Engineering, Chemical
Nontsikelelo Noxolo Tafu, Victoria A. Jideani
Summary: This study investigated the effects of different solid dispersion techniques and hydrophilic carriers on the crystallinity and thermal stability of MOLP, revealing potential applications in functional foods, beverages, and nutraceutical formulations. The results showed that PEGs enhanced the stability and intermolecular interactions in the solid dispersions.
Article
Biotechnology & Applied Microbiology
Teresa De Toni, Aaron A. Stock, Floriane Devaux, Grisell C. Gonzalez, Kailyn Nunez, Jessica C. Rubanich, Susan A. Safley, Collin J. Weber, Noel M. Ziebarth, Peter Buchwald, Alice A. Tomei
Summary: Pancreatic islet transplantation improves metabolic control and prevents complications in patients with brittle type 1 diabetes (T1D). Islet encapsulation can eliminate the need for immunosuppression. This study analyzed two microencapsulation platforms and found that capsule size and permselective materials affect insulin secretion. Anti-inflammatory modulation may be beneficial for small conformal capsules.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ahlem Meziadi, Navid Zuberi, Hendrick W. de Haan, Marc A. Gauthier
Summary: This study reveals that the inefficiency of bioconjugation reactions, such as protein PEGylation, is caused by the excluded volume effect (EVE) between methoxy poly(ethylene glycol) (mPEG) and proteins. The researchers found that this EVE leads to the self-assembly of proteins and reactive mPEG into separate protein-rich and mPEG-rich domains. By adding unreactive low-molecular weight mPEG as a co-solvent, the association between the larger protein and reactive mPEG can be promoted, resulting in improved reaction efficiency.
Article
Energy & Fuels
Chi Zhang, Chunhua Bai, Jian Yao
Summary: The adhesion of liquid fuel affects the separation of solid fuel particles, and the liquid component characteristics of mixed fuel have a significant impact on the combustion and explosion reactions. The study found that the liquid bridge force decreases with decreasing surface tension and liquid fuel volume, reducing the hindrance of liquid adhesion on dispersion. Increasing spray pressure also alleviates fuel agglomeration. Additionally, smaller fuel particles result in higher explosive overpressure and (dp/dt)(max). Therefore, effectively addressing the impact of liquid fuel adhesion on fuel dispersion can significantly accelerate the fuel reaction rate and promote energy transfer.
Article
Biochemistry & Molecular Biology
Niloufar Fattahi, Jeffrey Reed, Evan Heronemus, Priyasha Fernando, Ryan Hansen, Prathap Parameswaran
Summary: In this study, polyethylene glycol hydrogels were developed as protective coatings for electroactive biofilms, improving their viability under low resource conditions and ammonia-N shocks.
BIOELECTROCHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Marcos Arribas Perez, Paul A. Beales
Summary: The study demonstrates that SiO2 NPs can efficiently induce membrane fusion in biomimetic model membranes, likely by increasing lateral membrane tension. Real-time microscopy reveals three distinct mechanistic pathways for membrane fusion. SiO2 NPs show significant potential for inclusion in the synthetic biology toolkit for membrane remodeling and fusion in artificial cells.
Article
Chemistry, Physical
Xiaoyao Shen, Xiaoying Sun, Jing Liu, Jianzhong Hang, Lujiang Jin, Liyi Shi
Summary: The study introduces a new strategy using a hydrophobic-hydrophilic structure to achieve single-dispersed TiO2 particles in low viscosity systems without additives. The modified TiO2 particles maintain stability for at least 60 days and exhibit rheological properties similar to Newtonian fluids.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Engineering, Environmental
Guiying Tian, Huan Li, Bilal Khalid, Zijian Zhao
Summary: Blending Al-doped Li7La3Zr2O12 in PEG-LiClO4 matrix enhances ionic conductivity and cycling reversibility. Garnet oxide fillers enlarge amorphous region and improve electrochemical stability, facilitating rapid Li+ migration. The empirical equation proposed simulates the relationship of fillers' mass and volume ratios in composite electrolyte membrane.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Materials Science, Coatings & Films
Cheng-Lan Lin, An Chen
Summary: This study fabricates solid-state electrochromic devices (ECDs) with polyaniline and tungsten trioxide electrodes and succinonitrile/polyethylene glycol composite electrolytes. The EC properties of the devices, including modulation ability, response time, efficiency, and cycling stability, are investigated. The results demonstrate that the Pani-WO3 ECD using a SN/PEG composite electrolyte containing 10.0 wt% PEG exhibits the best performance.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Amel C. Ghogia, Lina M. Romero Millan, Claire E. White, Ange Nzihou
Summary: Understanding the mechanism of iron-catalyzed graphitization of biomass is crucial for large-scale synthesis of green graphene. The study reveals the direct effect of the iron molecular structure on the formation of highly graphitic carbon.
Article
Nanoscience & Nanotechnology
Ting Wang, Yuanyuan Zhen, Xiaoyu Ma, Biao Wei, Ning Wang
ACS APPLIED MATERIALS & INTERFACES
(2015)
Article
Pharmacology & Pharmacy
Ting Wang, Ning Wang
CURRENT PHARMACEUTICAL DESIGN
(2015)
Article
Immunology
Yuanyuan Zhen, Ning Wang, Zibin Gao, Xiaoyu Ma, Biao Wei, Yihui Deng, Ting Wang
Review
Pharmacology & Pharmacy
Ning Li, Ning Wang, Xueting Wang, Yuanyuan Zhen, Ting Wang
Meeting Abstract
Nanoscience & Nanotechnology
Ting Wang, Yuanyuan Zhen, Ning Li, Zhixuan Wang, Ning Wang
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2016)
Article
Biotechnology & Applied Microbiology
Xueting Wang, Ning Wang, Ning Li, Yuanyuan Zhen, Ting Wang
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2016)
Meeting Abstract
Chemistry, Multidisciplinary
Ning Wang, Yuanyuan Zhen, Ning Li, Xueting Wang, Ting Wang
JOURNAL OF CONTROLLED RELEASE
(2017)
Article
Chemistry, Multidisciplinary
Ning Wang, Yuanyuan Zhen, Yiguang Jin, Xueting Wang, Ning Li, Shaohong Jiang, Ting Wang
JOURNAL OF CONTROLLED RELEASE
(2017)
Article
Chemistry, Medicinal
Ning Li, Ning Wang, Tingni Wu, Changlu Qiu, Xueting Wang, Shaohong Jiang, Zina Zhang, Ting Liu, Chunliu Wei, Ting Wang
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2018)
Review
Chemistry, Multidisciplinary
Ning Wang, Minnan Chen, Ting Wang
JOURNAL OF CONTROLLED RELEASE
(2019)
Article
Immunology
Ning Wang, Changlu Qiu, Minnan Chen, Ting Liu, Ting Wang
Article
Polymer Science
Ning Wang, Chunliu Wei, Zina Zhang, Ting Liu, Ting Wang
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2020)
Article
Materials Science, Biomaterials
Yuanyuan Qi, Can Wang, Rui Qian, Minnan Chen, Pingping Jiang, Ting Wang, Ning Wang
Summary: The novel TUDC procedure allows for efficient loading of poorly water-soluble drugs into liposome interiors, with improved drug encapsulation efficiency. When combined with mathematical equations and thermodynamic process, it can accurately predict loading results, reducing experimental workload and enhancing liposome development efficiency.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Polymer Science
Jiale Li, Conghui Li, Hui Zhang, Xiang Gao, Ting Wang, Zengming Wang, Aiping Zheng
Summary: In this study, hot-melt extrusion was used to prepare azithromycin amorphous solid dispersion, solving the issues of bitter taste and low solubility. The selection of a suitable polymer was based on solubility parameter calculations, and the formulation and process were optimized using design of experiments.
Review
Pharmacology & Pharmacy
Ning Wang, Rui Qian, Ting Liu, Tingni Wu, Ting Wang
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS
(2019)
Article
Biochemistry & Molecular Biology
Raja Narayanasamy, Dandamudi Usharani, Ram Rajasekharan
Summary: This study investigated the role of ABHD16B in lipid metabolism. The overexpression of ABHD16B was found to decrease cellular triacylglycerol levels and increase phospholipid synthesis in yeast cells. Additionally, ABHD16B overexpression led to a reduction in lipid droplets and significant modifications in fatty acid composition. These findings highlight the importance of ABHD16B in lipid homeostasis and provide insights into its regulatory function in cellular lipid metabolism.
CHEMISTRY AND PHYSICS OF LIPIDS
(2024)