Recent advances in the synthesis of pyrroles by multicomponent reactions

Pseudilins: Halogenated, Allosteric Inhibitors of the Non-Mevalonate Pathway Enzyme IspD

(2014) Andrea Kunfermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

(2013) F Basit et al.   CELL DEATH AND DIFFERENTIATION

Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles

(2013) Anton V. Gulevich et al.   CHEMICAL REVIEWS

Stereoselective Multiple Bond-Forming Transformations (MBFTs): The Power of 1,2- and 1,3-Dicarbonyl Compounds

(2013) Damien Bonne et al.   CHEMISTRY-A EUROPEAN JOURNAL

DABCO-promoted facile and convenient synthesis of novel isoxazolyl-1H-2,3-pyrrole dicarboxylates

(2013) Rajanarendar Eligeti et al.   CHINESE CHEMICAL LETTERS

One-pot synthesis of highly substituted pyrroles using nano copper oxide as an effective heterogeneous nanocatalyst

(2013) Hamid Saeidian et al.   COMPTES RENDUS CHIMIE

Pyrrole: Chemical Synthesis, Microwave Assisted Synthesis, Reactions and Applications: A Review

(2013) Shrinivas Joshi et al.   CURRENT ORGANIC CHEMISTRY

New Pyrrole Alkaloids with BulkyN-Alkyl Side Chains Containing Stereogenic Centers fromLycium chinense

(2013) Ui Joung Youn et al.   HELVETICA CHIMICA ACTA

Design, synthesis and antistaphylococcal activity of marine pyrrole alkaloid derivatives

(2013) Rajesh A. Rane et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Ionic Liquid Promoted Multicomponent Reaction: A Good Strategy for the Eco-Compatible Synthesis of Functionalized Pyrroles

(2013) I. R. Siddiqui et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

General and Regioselective Synthesis of Pyrroles via Ruthenium-Catalyzed Multicomponent Reactions

(2013) Min Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Chemoselective Synthesis of Polysubstituted Pyrroles via Isocyanide-Based Multicomponent Domino Reaction

(2013) Xiang Wang et al.   ORGANIC LETTERS

A Novel Tandem Sequence to Pyrrole Syntheses by 5-endo-dig Cyclization of 1,3-Enynes with Amines

(2013) Ganesan Bharathiraja et al.   ORGANIC LETTERS

Exploitation of Dual Character of CN Moiety in the Synthesis of Uniquely Decorated 3H-Pyrroles: A Rare Observation

(2013) Paramita Das et al.   ORGANIC LETTERS

Improved Catalyst-Free Synthesis of Pyrrole Derivatives in Aqueous Media

(2013) Fatemeh Tamaddon et al.   SYNLETT

Three-Component Coupling Synthesis of Diversely Substituted N-Aryl Pyrroles Catalyzed by Iron(III) Chloride

(2013) Soumen Sarkar et al.   SYNTHETIC COMMUNICATIONS

Synthesis of pyrrole-2,3,4,5-tetracarboxylates via a copper-catalyzed reaction of amine with but-2-ynedioate

(2013) Ling Zhang et al.   TETRAHEDRON

One-pot four-component synthesis of highly substituted pyrroles in gluconic acid aqueous solution

(2013) Bao-Le Li et al.   TETRAHEDRON

Modular CeCl3·7H2O-catalyzed multi-component synthesis of 1,2,3,4-tetrasubstituted pyrroles under microwave irradiation and their further trichloroisocyanuric acid-mediated conversion into 5-sulfenylpyrrole derivatives

(2013) Claudio C. Silveira et al.   TETRAHEDRON

The marinopyrroles

(2013) Derrick L.J. Clive et al.   TETRAHEDRON

Catalyst-free four-component protocol for the synthesis of substituted pyrroles under reusable reaction media

(2013) H.M. Meshram et al.   TETRAHEDRON LETTERS

An efficient and convenient synthesis of 1,2,3-trisubstituted pyrroles via iodocyclization from ethyl acetoacetate

(2013) Pengfei Xu et al.   TETRAHEDRON LETTERS

A catalyst- and solvent-free three-component reaction for the regioselective one-pot access to polyfunctionalized pyrroles

(2013) Subrahmanya Ishwar Bhat et al.   TETRAHEDRON LETTERS

Ceric (IV) ammonium nitrate (CAN) mediated synthesis of pyrrole-2,3,4,5-tetracarboxylates by reaction of dimethyl acetylenedicarboxylate with an amine

(2013) Sridhar Madabhushi et al.   TETRAHEDRON LETTERS

Heterogenized tungsten complex: an efficient and high yielding catalyst for the synthesis of structurally diverse tetra substituted pyrrole derivatives via four-component assembly

(2013) Amol B. Atar et al.   TETRAHEDRON LETTERS

Three-component direct synthesis of substituted pyrroles from easily accessible chemical moieties using hypervalent iodine reagent

(2013) Nikhil C. Jadhav et al.   TETRAHEDRON LETTERS

Montmorillonite clay catalyzed synthesis of functionalized pyrroles through domino four-component coupling of amines, aldehydes, 1,3-dicarbonyl compounds and nitroalkanes

(2013) Jaideep B. Bharate et al.   RSC Advances

Three-component domino reactions providing rapid and efficient routes to fully substituted pyrroles

(2013) Jia-Yan Liu et al.   RSC Advances

Three-component Synthesis of FunctionalizedN-Protected Tetrasubstituted Pyrroles by an Addition-Elimination-Aromatization Process

(2013) Dhananjay R. Magar et al.   Asian Journal of Organic Chemistry

Iron-Catalyzed Tandem One-Pot Addition and Cyclization of the Blaise Reaction Intermediate and Nitroolefins: Synthesis of Substituted NH-Pyrroles from Nitriles

(2012) Mi-Na Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Selective Ruthenium-Catalyzed Three-Component Synthesis of Pyrroles

(2012) Min Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-mediated functionalization of polysubstituted pyrroles: Their evaluation as potential inhibitors of PDE4

(2012) T. Bhaskar Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of 2,3,4-trisubstituted pyrroles via a facile reaction of vinyl azides and tosylmethyl isocyanide

(2012) Wenteng Chen et al.   CANADIAN JOURNAL OF CHEMISTRY

Modular Three-Component Organocatalytic Synthesis of 3,4-Disubstituted Pyrroles by a One-Pot Domino Reaction

(2012) Cecilia Martín-Santos et al.   ChemCatChem

Three-component access to pyrroles promoted by the CAN–silver nitrate system under high-speed vibration milling conditions: a generalization of the Hantzsch pyrrole synthesis

(2012) Verónica Estévez et al.   CHEMICAL COMMUNICATIONS

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Recent developments in asymmetric multicomponent reactions

(2012) Corien de Graaff et al.   CHEMICAL SOCIETY REVIEWS

A walk around the A3-coupling

(2012) Vsevolod A. Peshkov et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of highly functionalized pyrroles from primary amines and activated acetylenes in water

(2012) S. Zahra Sayyed-Alangi et al.   CHINESE CHEMICAL LETTERS

Novel and efficient supramolecular synthesis of pyrroles in the presence of β-cyclodextrin in water

(2012) K. Ramesh et al.   CHINESE CHEMICAL LETTERS

A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

(2012) Hossein Anaraki-Ardakani et al.   E-Journal of Chemistry

Recent Advances in Asymmetric Isocyanide-Based Multicomponent Reactions

(2012) Sander S. van Berkel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Three-component synthesis of substituted β-(trifluoromethyl)pyrroles via Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonylic compounds and ammonia or primary amines

(2012) Vladislav Yu. Korotaev et al.   JOURNAL OF FLUORINE CHEMISTRY

Molybdate sulfuric acid as a reusable solid catalyst in the synthesis of 2,3,4,5-tetrasubstituted pyrroles via a new one-pot [2+2+1] strategy

(2012) Fatemeh Tamaddon et al.   JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

CeCl3·7H2O Catalyzed C–C and C–N Bond-Forming Cascade Cyclization with Subsequent Side-Chain Functionalization and Rearrangement: A Domino Approach to Pentasubstituted Pyrrole Analogues

(2012) Dipankar Dhara et al.   JOURNAL OF ORGANIC CHEMISTRY

A Palladium Iodide-Catalyzed Carbonylative Approach to Functionalized Pyrrole Derivatives

(2012) Bartolo Gabriele et al.   JOURNAL OF ORGANIC CHEMISTRY

Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade

(2012) Heiner Eckert   MOLECULES

A New Three-Component Reaction Catalyzed by Silica Sulfuric Acid: Synthesis of Tetrasubstituted Pyrroles

(2012) Fatemeh Tamaddon et al.   SYNLETT

Three-Component Reaction of Triphenylphosphine, Dialkyl Acetylenedicarboxylate, and 2-Aminothiazole or 2-Aminobenzothiazole in the Presence of Arylglyoxals: An Efficient One-Pot Synthesis of Highly Functionalized Pyrroles

(2012) Mohammad Anary-Abbasinejad et al.   SYNTHETIC COMMUNICATIONS

Efficient synthesis of pentasubstituted pyrroles via one-pot reactions of arylamines, acetylenedicarboxylates, and 3-phenacylideneoxindoles

(2012) Ying Han et al.   TETRAHEDRON

Synthesis of 2,3-dicarbonylated pyrroles and furans via the three-component Hantzsch reaction

(2012) Thomas A. Moss et al.   TETRAHEDRON LETTERS

Synthesis of tetra-substituted pyrroles, a potential phosphodiesterase 4B inhibitor, through nickel(II) chloride hexahydrate catalyzed one-pot four-component reaction

(2012) Abu T. Khan et al.   TETRAHEDRON LETTERS

Iodine catalyzed four-component reaction: a straightforward one-pot synthesis of functionalized pyrroles under metal-free conditions

(2012) G. Rajeshwar Reddy et al.   RSC Advances

Yb(OTf)3 mediated MCR: a new and regioselective approach towards polysubstituted pyrroles of pharmacological interest

(2012) G. Rajeshwar Reddy et al.   RSC Advances

A Novel Assembly of Substituted Pyrroles by Acid-Catalyzed Sequential Three-Component Reaction of Amines, Alkynoates, and 1,2-Diaza-1,3-dienes

(2011) Orazio A. Attanasi et al.   ADVANCED SYNTHESIS & CATALYSIS

Pd-mediated new synthesis of pyrroles: their evaluation as potential inhibitors of phosphodiesterase 4

(2011) G. Rajeshwar Reddy et al.   CHEMICAL COMMUNICATIONS

A straightforward one-pot multicomponent synthesis of polysubstituted pyrroles

(2011) Xufeng Lin et al.   CHEMICAL COMMUNICATIONS

Direct synthesis of pyrroles via a silver-promoted three-component reaction involving unusual imidazole ring opening

(2011) Jing Zeng et al.   CHEMICAL COMMUNICATIONS

Synthesis and Biological Activity of Lamellarin Alkaloids: An Overview

(2011) Masatomo Iwao et al.   HETEROCYCLES

Synthesis of Functionalized Pyrroles via Catalyst- and Solvent-Free Sequential Three-Component Enamine−Azoene Annulation

(2011) Orazio A. Attanasi et al.   JOURNAL OF ORGANIC CHEMISTRY

Three-Component Synthesis of Polysubstituted Pyrroles from α-Diazoketones, Nitroalkenes, and Amines

(2011) Deng Hong et al.   ORGANIC LETTERS

One-Pot Multicomponent Synthesis of Diversely Substituted 2-Aminopyrroles. A Short General Synthesis of Rigidins A, B, C, and D

(2011) Liliya V. Frolova et al.   ORGANIC LETTERS

A Simple and Efficient Metal-Free Synthesis of Tetrasubstituted Pyrroles by Iodine-Catalyzed Four-Component Coupling Reaction of Aldehydes, Amines, Dialkyl Acetylenedicarboxylates, and Nitromethane¹

(2011) Biswanath Das et al.   SYNTHESIS-STUTTGART

An efficient one-pot synthesis of tetra-substituted pyrroles

(2011) Elmira Ghabraie et al.   TETRAHEDRON

DABCO-promoted three-component reaction between amines, dialkyl acetylenedicarboxylates, and glyoxal

(2011) K. Ramesh et al.   TETRAHEDRON LETTERS

A facile strategy for the one pot multicomponent synthesis of spiro dihydropyridines from amines and activated alkynes

(2011) Selvarangam E. Kiruthika et al.   TETRAHEDRON LETTERS

Polyethylene glycol (PEG-400) as an efficient and recyclable reaction medium for one-pot synthesis of polysubstituted pyrroles under catalyst-free conditions

(2011) Lingaiah Nagarapu et al.   TETRAHEDRON LETTERS

Homogeneous and heterogeneous catalysts for multicomponent reactions

(2011) Maria José Climent et al.   RSC Advances

Design of a Versatile Multicomponent Reaction Leading to 2-amino-5-ketoaryl pyrroles

(2010) Kan Wang et al.   Chemical Biology & Drug Design

Domino allylic amination/Sonogashira/heterocyclisation reactions: palladium-catalysed three-component synthesis of pyrroles

(2010) Sandrine Lamandé-Langle et al.   CHEMICAL COMMUNICATIONS

Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis

(2010) Vellaisamy Sridharan et al.   CHEMICAL REVIEWS

Multicomponent reactions for the synthesis of pyrroles

(2010) Verónica Estévez et al.   CHEMICAL SOCIETY REVIEWS

Multicomponent Reactions for the Synthesis of Heterocycles

(2010) Bo Jiang et al.   Chemistry-An Asian Journal

Recent advances in multicomponent reactions for diversity-oriented synthesis

(2010) James E. Biggs-Houck et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Iron(III)-Catalyzed Four-Component Coupling Reaction of 1,3-Dicarbonyl Compounds, Amines, Aldehydes, and Nitroalkanes: A Simple and Direct Synthesis of Functionalized Pyrroles

(2010) Sukhendu Maiti et al.   JOURNAL OF ORGANIC CHEMISTRY

Reaction of isocyanides with thiophenols and gem-diactivated olefins: a one-pot synthesis of substituted 2-aminopyrroles

(2010) Anna N. Kolontsova et al.   MOLECULAR DIVERSITY

One-pot highly efficient synthesis of substituted pyrroles and N-bridgehead pyrroles by zinc-catalyzed multicomponent reaction

(2010) Xiao-tao Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-Step Continuous Flow Synthesis of Highly Substituted Pyrrole-3-carboxylic Acid Derivatives via in Situ Hydrolysis oftert-Butyl Esters

(2010) Ananda Herath et al.   ORGANIC LETTERS

One-Pot AgOAc-Mediated Synthesis of Polysubstituted Pyrroles from Primary Amines and Aldehydes: Application to the Total Synthesis of Purpurone

(2010) Qingjiang Li et al.   ORGANIC LETTERS

Horner−Wadsworth−Emmons Reagents as Azomethine Ylide Analogues: Pyrrole Synthesis via (3 + 2) Cycloaddition

(2010) Marie S. T. Morin et al.   ORGANIC LETTERS

Total Synthesis of Lamellarins D, H, and R and Ningalin B

(2010) Qingjiang Li et al.   ORGANIC LETTERS

A Novel Indium-Catalyzed Three-Component Reaction: General and Efficient One-Pot Synthesis of Substituted Pyrroles

(2010) Min Lin et al.   SYNLETT

An Efficient New Method for the Synthesis of Polysubstituted Pyrroles¹

(2010) Biswanath Das et al.   SYNTHESIS-STUTTGART

Efficient Route for the Synthesis of Highly Substituted Pyrroles

(2010) Javad Azizian et al.   SYNTHETIC COMMUNICATIONS

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

Multi-component cycloaddition approaches in the catalytic asymmetric synthesis of alkaloid targets

(2009) Stéphane Perreault et al.   CHEMICAL SOCIETY REVIEWS

A Submarine Journey: The Pyrrole-Imidazole Alkaloids

(2009) Barbara Forte et al.   Marine Drugs

Efficient and green synthesis of tetrasubstituted pyrroles promoted by task-specific basic ionic liquids as catalyst in aqueous media

(2009) Issa Yavari et al.   MOLECULAR DIVERSITY

One-Pot Silver-Catalyzed and PIDA-Mediated Sequential Reactions: Synthesis of Polysubstituted Pyrroles Directly from Alkynoates and Amines

(2009) Weibing Liu et al.   ORGANIC LETTERS

A Novel Approach to the Synthesis of Highly Functionalized Pyrroles

(2009) Mohammad Anary-Abbasinejad et al.   SYNLETT

Indium(III) Chloride-Catalyzed Propargylation/Amination/Cycloisomerization Tandem Reaction: One-Pot Synthesis of Highly Substituted Pyrroles from Propargylic Alcohols, 1,3-Dicarbonyl Compounds and Primary Amines

(2008) Xiao-tao Liu et al.   ADVANCED SYNTHESIS & CATALYSIS