Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1

An Updated View of Cisplatin Transport

(2013) Fabio Arnesano et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Interaction of cisplatin and analogue Pt(en)Cl2 with the copper metallo-chaperone Atox1

(2013) Chak Ming Sze et al.   Metallomics

PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide

(2013) Guolin Ma et al.   Metallomics

Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking

(2013) Maria E. Palm-Espling et al.   PLoS One

Reaction of platinum anticancer drugs and drug derivatives with a copper transporting protein, Atox1

(2012) Maria E. Palm-Espling et al.   BIOCHEMICAL PHARMACOLOGY

Interactions of anticancer Pt compounds with proteins: an overlooked topic in medicinal inorganic chemistry?

(2012) Angela Casini et al.   Chemical Science

Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

(2011) Oleg Y. Dmitriev   Biochemistry and Cell Biology

Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila

(2011) Haiqing Hua et al.   BIOMETALS

The anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin

(2011) Wenbing Hu et al.   CHEMICAL COMMUNICATIONS

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

(2011) Fabio Arnesano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro

(2011) M. E. Palm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

Crystal Structures of Cisplatin Bound to a Human Copper Chaperone

(2009) Amie K. Boal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrathiomolybdate Inhibits Copper Trafficking Proteins Through Metal Cluster Formation

(2009) H. M. Alvarez et al.   SCIENCE

Characterisation of Cisplatin Binding Sites in Human Serum Proteins Using Hyphenated Multidimensional Liquid Chromatography and ESI Tandem Mass Spectrometry

(2008) Joanna Will et al.   ChemMedChem

Novel Role of Antioxidant-1 (Atox1) as a Copper-dependent Transcription Factor Involved in Cell Proliferation

(2008) Shinichi Itoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of the loss of Atox1 on the cellular pharmacology of cisplatin

(2008) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY