Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro

Unification of the Copper(I) Binding Affinities of the Metallo-chaperones Atx1, Atox1, and Related Proteins

(2011) Zhiguang Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The challenges of determining metal–protein affinities

(2010) Zhiguang Xiao et al.   NATURAL PRODUCT REPORTS

Affinity gradients drive copper to cellular destinations

(2010) Lucia Banci et al.   NATURE

The soluble metal-binding domain of the copper transporter ATP7B binds and detoxifies cisplatin

(2009) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Therapeutic Targeting of ATP7B in Ovarian Carcinoma

(2009) L. S. Mangala et al.   CLINICAL CANCER RESEARCH

Functional Interactions of Cu-ATPase ATP7B with Cisplatin and the Role of ATP7B in the Resistance of Cells to the Drug

(2009) Karoline Leonhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysine-60 in Copper Chaperone Atox1 Plays an Essential Role in Adduct Formation with a Target Wilson Disease Domain

(2009) Faiza Hussain et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal Structures of Cisplatin Bound to a Human Copper Chaperone

(2009) Amie K. Boal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct determination of the primary binding site of cisplatin on cytochrome c by mass spectrometry

(2009) Ting Zhao et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Increased sensitivity to platinating agents and arsenite in human ovarian cancer by downregulation of ASNA1

(2009) Hemmingsson   ONCOLOGY REPORTS

Tetrathiomolybdate Inhibits Copper Trafficking Proteins Through Metal Cluster Formation

(2009) H. M. Alvarez et al.   SCIENCE

ASNA1, an ATPase targeting tail-anchored proteins, regulates melanoma cell growth and sensitivity to cisplatin and arsenite

(2008) O. Hemmingsson et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

[1H,15N] Heteronuclear Single Quantum Coherence NMR Study of the Mechanism of Aquation of Platinum(IV) Ammine Complexes

(2008) Murray S. Davies et al.   INORGANIC CHEMISTRY

Interaction of cisplatin and analogues with a Met-rich protein site

(2008) Chak Ming Sze et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Effects of the loss of Atox1 on the cellular pharmacology of cisplatin

(2008) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Extreme Temperature Tolerance of a Hyperthermophilic Protein Coupled to Residual Structure in the Unfolded State

(2008) Marcus Wallgren et al.   JOURNAL OF MOLECULAR BIOLOGY