Asymmetric domino synthesis of indanes bearing four contiguous stereocentres catalyzed by sub-mol% loadings of a squaramide in minutes

A New Henry/Michael/Retro-Henry/Henry Domino Sequence Promoted by Bifunctional Organocatalysts

(2013) Arianna Quintavalla et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic asymmetric domino Michael–Henry reaction for the synthesis of substituted bicyclo[3.2.1]octan-2-ones

(2013) Michail Tsakos et al.   CHEMICAL COMMUNICATIONS

Asymmetric Organocatalytic Michael/Henry Domino Reactions through Hydrogen-Bond Activation: Kinetic Access to Indane Scaffolds Bearingcis-Vicinal Substituents

(2013) Charles C. J. Loh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Organocatalytic Michael Addition/Cyclization Cascade Reaction of Ylideneoxindoles with Isothiocyanato Oxindoles: A Formal [3+2] Cycloaddition Approach to Optically Active Bispirooxindole Derivatives

(2013) Fen Tan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter

(2013) Pankaj Chauhan et al.   TETRAHEDRON-ASYMMETRY

Development of Cascade Reactions for the Concise Construction of Diverse Heterocyclic Architectures

(2012) Liang-Qiu Lu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Recent Developments in Asymmetric Organocatalytic Domino Reactions

(2012) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

(2012) Hui Qian et al.   CHEMICAL COMMUNICATIONS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

One-Pot Sequential Organocatalysis: Highly Stereoselective Synthesis of Trisubstituted Cyclohexanols

(2012) Qipu Dai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Michael Addition of N-Boc-Protected Oxindoles to Nitroalkenes Catalyzed by a Chiral Secondary Amine

(2012) Chuan Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Assembly of Spirooxindole Derivatives Containing Four Consecutive Stereocenters via Organocatalytic Michael–Henry Cascade Reactions

(2012) Klaus Albertshofer et al.   ORGANIC LETTERS

Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea

(2011) Tao Zhang et al.   CHEMICAL COMMUNICATIONS

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Amino-Indanol-Catalyzed Asymmetric Michael Additions of Oxindoles to Protected 2-Amino-1-nitroethenes for the Synthesis of 3,3′-Disubstituted Oxindoles Bearing α,β-Diamino Functionality

(2011) Xiong-Li Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereo- and Enantioselective Conjugate Addition of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Ni(OAc)2-Diamine Complex under Mild Conditions

(2011) Yan-Yan Han et al.   ORGANIC LETTERS

Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefins

(2011) Miao Ding et al.   Chemical Science

Asymmetric Michael Addition Reaction of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Alkyl- Substituted Thiourea Catalyst

(2010) Xin Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Domino Michael-Henry Reaction: Enantioselective Access to Bicycles with Consecutive Quaternary Centers by Using Bifunctional Catalysts

(2010) Magnus Rueping et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Conjugate Addition of Oxindoles to 2-Chloroacrylonitrile: A Highly Effective Organocatalytic Strategy for Simultaneous Construction of 1,3-Nonadjacent Stereocenters Leading to Chiral Pyrroloindolines

(2010) Xin Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Acyl Phosphonates: Good Hydrogen Bond Acceptors and Ester/Amide Equivalents in Asymmetric Organocatalysis

(2010) Hao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Facile Domino Access to Chiral Bicyclo[3.2.1]octanes and Discovery of a New Catalytic Activation Mode

(2010) Bin Tan et al.   ORGANIC LETTERS

Highly Diastereo- and Enantioselective Michael Additions of 3-Substituted Oxindoles to Maleimides Catalyzed by Chiral Bifunctional Thiourea−Tertiary Amine

(2010) Yu-Hua Liao et al.   ORGANIC LETTERS

Organocatalytic asymmetric assembly reactions for the syntheses of carbohydrate derivatives by intermolecular Michael-Henry reactions

(2010) H. Uehara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

One-Pot Synthesis of Pentasubstituted Cyclohexanes by a Michael Addition Followed by a Tandem Inter-Intra Double Henry Reaction

(2009) José Luis García Ruano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Iminium Ion Catalysis with a Novel Bifunctional Primary Amine Thiourea: Controlling Adjacent Quaternary and Tertiary Stereocenters

(2009) Patrizia Galzerano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Base-Free Phase-Transfer Reaction in Water-Rich Solvent

(2009) Rongjun He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiourea-Catalyzed Highly Enantio- and Diastereoselective Additions of Oxindoles to Nitroolefins: Application to the Formal Synthesis of (+)-Physostigmine

(2009) Tommy Bui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2,3,4-Trisubstituted Thiochromanes using an Organocatalytic Enantioselective Tandem Michael-Henry Reaction

(2008) Rajasekhar Dodda et al.   ADVANCED SYNTHESIS & CATALYSIS

A Novel Enantioselective Catalytic Tandem Oxa-Michael-Henry Reaction: One-Pot Organocatalytic Asymmetric Synthesis of 3-Nitro-2H-chromenes

(2008) Dan-Qian Xu et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

(2008) Jeremiah P. Malerich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Highly Diastereo- and Enantioselective Synthesis of Multisubstituted Cyclopentanes with Four Chiral Carbons by the Organocatalytic Domino Michael−Henry Reaction

(2008) Bin Tan et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Tandem Michael−Henry Reactions: A Highly Stereoselective Synthesis of Multifunctionalized Cyclohexanes with Two Quaternary Stereocenters

(2008) Bin Tan et al.   ORGANIC LETTERS